1 results match your criteria: "University College London and the Edward Jenner Institute for Vaccine Research[Affiliation]"
Development of the antibody response in acute HIV-1 infection.
AIDS
February 2004
Department of Immunology, University College London and the Edward Jenner Institute for Vaccine Research, Compton, UK.
Background: Cytotoxic T lymphocytes have been shown to reduce viraemia during acute HIV-1 infection; however the role of neutralizing antibodies in this process is unclear. One confounding factor may be artefacts introduced by viral culture.
Objective: To assess the development of autologous neutralizing and non-neutralizing antibodies following acute HIV-1 infection using recombinant viruses with envelopes amplified directly from patient peripheral blood mononuclear cells, thereby avoiding in vitro selection.