4 results match your criteria: "University College London (UCL) Institute of Child Health and Great Ormond Street[Affiliation]"

Background: Cyclic Vomiting Syndrome (CVS) is a rare functional gastrointestinal disorder, which has a considerable burden on quality of life of both children and their family. Aim of the study was to evaluate the diagnostic modalities and therapeutic approach to CVS among Italian tertiary care centers and the differences according to subspecialties, as well as to explore whether potential predictive factors associated with either a poor outcome or a response to a specific treatment.

Methods: Cross-sectional multicenter web-based survey involving members of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP).

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In the last decade, the role of nutritional management in pediatric gastrointestinal diseases has gained increasing popularity. Disease-specific diets have been introduced as conventional treatments by international guidelines. Patients tend to more willingly accept food-based therapies than drugs because of their relatively "harmless" nature.

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Cyclic Vomiting Syndrome in Children.

Front Neurol

November 2020

Chair of Pediatrics, Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Faculty of Medicine & Psychology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.

Cyclic Vomiting Syndrome (CVS) is an underdiagnosed episodic syndrome characterized by frequent hospitalizations, multiple comorbidities, and poor quality of life. It is often misdiagnosed due to the unappreciated pattern of recurrence and lack of confirmatory testing. CVS mainly occurs in pre-school or early school-age, but infants and elderly onset have been also described.

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Article Synopsis
  • High-field MRI at 9.4 T offers significantly better image quality and tissue contrast for evaluating small human fetuses compared to conventional MRI at 1.5 T.
  • A study involving 18 fetuses showed that all detected abnormalities via invasive autopsy corresponded with findings from high-field MRI, while 78% of cases were missed using conventional MRI.
  • High-field MRI shows promise as a minimally invasive alternative for perinatal autopsies, effectively providing good tissue characterization even for very small fetuses.
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