High prevalence of early chronic kidney disease in high risk outpatients.

Introduction: Chronic kidney disease (CKD) is a significant public health problem. The aim of this study was to determine the presence of early stages of renal disease in hypertensive and diabetic outpatients without previously diagnosed renal damages.

Methods: In this cross-sectional study we studied a random sample of outpatients with essential hypertension and/or diabetes mellitus type 2 in the general practice ambulance of city Sarajevo.

Clinical analysis of etiology, risk factors and outcome in patients with acute kidney injury.

Introduction: Acute kidney injury is characterized by a rapid loss of renal excretory function with the increase of nitrogen compounds in the blood and with different outcome.

Objective: Since descriptions of the risk factors and sequelae of acute kidney injury (AKI) remain relatively limited, the objective of this study was to determine etiology and clinical characteristics of AKI, as well as risk factors for adverse outcome of renal function and death in AKI patients.

Methods: We retrospectively studied a cohort of 84 adult AKI patients admitted to Nephrology Clinic in University Clinical Centre Sarajevo during period 2012-2014.

Renal Function Outcome Prognosis in Septic and Non-septic Acute Kidney Injury Patients.

Aim: The objective of this study was to evaluate prognostic impact of clinical factors on outcome of renal function in septic and non-septic acute kidney injury (AKI) patients.

Methods: The prospective, observational, clinical study was performed at Nephrology Clinic and Clinic for Infectious Diseases, University Clinical Centre Sarajevo. One hundred patients with diagnosis of AKI were enrolled in the study, and divided into two groups: septic and non-septic AKI patients.

Potential coverage of circulating HPV types by current and developing vaccines in a group of women in Bosnia and Herzegovina with abnormal Pap smears.

The objectives of this study were to identify human papillomavirus (HPV) genotypes in a group of Bosnian-Herzegovinian women with abnormal cytology and to assess their potential coverage by vaccines. HPVs were identified by multiplex real-time PCR test (HPV High Risk Typing Real-TM; Sacace Biotechnologies, Italy) of 105 women with an abnormal cervical Pap smear and positive high-risk (HR) HPV DNA screening test. The most common genotypes in the study were HPV-16 (32·6%, 48/147), HPV-31 (14·3%, 21/147), HPV-51 (9·5%, 14/147) and HPV-18 (7·5%, 11/147).

Short-term Parameters of Heart Rate Variability During Balanced Anaesthesia with Administration of Two Different Inhalation Anaesthetics.

Introduction: Heart rate variability which denotes variations of the length of consecutive heart cycles has been suggested to reflect the modulation of heart rate by autonomic nervous system.

Methods: Sixty four patients of ASA I and ASA II status scheduled for elective abdominal surgical procedures were randomly allocated to group 1 and group 2. Premedication and induction of anaesthesia were performed with same agents.

Mitral valve replacement in a patient with infective endocarditis and aneurysm of the cerebral artery: a case report.

Objective: Endocarditis can have profound and devastating neurological consequences, with the vast majority of these complications in patients with left-sided valvular disease. The approach to the acute management of stroke in children with infective endocarditis is limited by the inadequacy of published data on their clinical course and outcome.

Case Report: This case report presents a 12 year old girl with diagnosed endocarditis, complicated with intracranial hemorrhage, due to the rupture of an aneurysm of the peripheral branch medial cerebral artery and gradient therapeutic approach, with an excellent final result.

Clinical importance of independent prognostic factors for renal parenchymal carcinoma and a possibility of predicting the treatment outcome.

Aim: To determine the influence of independent predictors (nuclear grade, patient’s general condition, tumor size) on survival of patients suffering from renal cancer.

Methods: The study included 158 patients treated for renal parenchymal carcinoma in the period between 01. 01.

Alterations of short-term heart rate variability in periinduction period of general anaesthesia with two intravenous anaesthetics.

Introduction: Alterations of the parameters of heart rate variability, phenomenon associated with autonomic nervous system balance, have been shown as a possibly very important factor for monitoring of cardiocirculatory system in the perioperative period. Periinduction period of general anaesthesia is very important with significant changes of haemodynamics what could be reflected in the changes of the parameter of heart rate variability.

Methods: A hundred patients of ASA I and ASA II status who were scheduled for elective abdominal surgical procedures of moderate stress response, were randomly assigned to group I and group II, who were administered propofol or thiopentone as induction anaesthetic, respectively.

Clinical importance of dependent prognostic factors for renal parenchymal carcinoma and a possibility of predicting the treatment outcome.

Aim: To determine an influence of dependent predictors (clinical presentation, stage, pH type) on survival of patients suffering from renal carcinoma.

Methods: The research included 158 patients who had been treated for carcinoma of renal parenchyma in the period between 1 January 1998 and 31 December 2011. A disease stage was determined according to the guidelines of the American Joint Committee on Cancer (AJCC).

Outcome of patients with infantile spasms.

Purpose: To assess outcome of children diagnosed with infantile spasms (IS) during the six-year-period (2002-20006), at the Pediatric Clinic of Clinical Center of University of Sarajevo, as well as to present other important clinical characteristics in this group of patients.

Methods: All patients had medical histories with detailed description orvideo recordings of their seizures, as well as profound neurological exam, series of video-EEG registrations, neuroimaging studies and laboratory studies that were possible to perform.

Results: Total of 19 patients with IS were treated (14 male, 5 female).

Some historical remarks and current state of mental health services in bosnia and herzegovina.

In this paper we have presented historical overview of development of psychiatric services in Bosnia and Herzegovina. Special attention was given to the recent war destruction (l992-l995), as well as to the reconstruction and reform of mental health services within a frame of newly introduced mental health strategy.

Observational postmarketing study on efficacy and safety of novel generic risperidone risset(r) in patients with acute or chronic schizophrenic or other related psychosis.

Objective. The aim of this study was to establish the effectiveness and safety of risperidone (Risset(R) - PLIVA) in patients with acute or chronic schizophrenic or other related psychosis. Study was designed as postmarketing, 4-week, open-label, flexible-dose observational study.

Specific characteristics of the group psychotherapy of neurotic patients who survived war traumatization.

The paper will show specific characteristics of the psychodynamic group psychotherapy in the small group of patients. Primary indications for the psychotherapy were expressed neurotic disorders. All patients have survived war traumatization, and some survived trauma of being refugee and separation from the other family members.

Specific differences in trauma related symptoms between war veterans and the civilian population.

Aim: The aim of this study was to determine specific differences in trauma related symptoms between the civilians who survived the trauma of war and veterans of war who have had the experience of combat stress.

Methods: The study involved two groups of subjects, with 50 male subjects in the age range between 20 and 50 in each group who had no psychiatric history prior to traumatization. All subjects were assessed for psychopathological symptoms using the multidimensional instrument for symptom assessment SCL 90-R (L.

Specific differences in trauma related symptoms between the refugees survivors of torture and refugees of war.

Aim: The aim of this study was to determine specific differences in trauma related symptoms in a group of subjects who were survivors of torture and displacement compared with a group of subjects who survived displacement as a consequence of state sponsored violence in Bosnia and Herzegovina.

Subjects: The subjects were divided in two groups of 50 adult survivors; one group comprising of 50 survivors of displacement and torture, the other group of 50 survivors of displacement who did not experience torture. The age range of the subjects was between 20 and 60.

Impact of war traumatic events on the socio-demographic characteristics of the civilian population in bosnia and herzegovina.

Aim: The aim of the present contribution is to present the socio-demographic characteristics of the torture survivors and specific life changes caused by the torture, and to create real assumptions for adequate socio-medical treatment.

Subjects And Methods: The present research was carried out in the Psychiatric clinic in Sarajevo with patients who were victims of torture during the aggression on Bosnia and Herzegovina, who were treated after the aggression for psychological and physical disorders. Socio-demographic data were collected by applying the specially constructed General Questionnaire consisting of 28 questions, prior to the psychiatric interview.