859 results match your criteria: "University Clinical Center of Serbia[Affiliation]"

Introduction: Hidradenitis suppurativa (HS) is a chronic skin disease marked by recurrent abscesses, sinus tracts, and scarring, often accompanied by systemic symptoms. Diagnosed clinically, HS affects around 0.4% of people in western populations, but standardized treatment options are limited, leading to inconsistent outcomes.

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Purpose: Management of giant inguinoscrotal hernia (GIH) is still a challenging procedure associated with a higher risk of intraabdominal hypertension and abdominal compartment syndrome as a life-threatening condition. The aim of the study was to present our management strategy for GIH.

Methods: This is a retrospective review of a case series including 24 consecutive patients with 25 GIH who underwent reconstructive surgery from January 2006 to June 2023, at the University Clinic for Digestive Surgery and Hernia Center Zuvela.

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Renal artery thrombosis is an uncommon but serious cause of acute kidney injury that can result in permanent loss of function. It is frequently misdiagnosed due to its non-specific appearance, which can mimic renal colic and other more common causes of abdominal pain. There is no agreement on the first-line treatment and no prospective studies comparing thrombolysis, anticoagulation and embolectomy.

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Introduction: Brucellosis is one of the most common zoonotic infections in the world. Cardiac complications of the disease are usually in the form of endocarditis, and, to a lesser extent, in the form of myopericarditis.

Case: We report the case of a 34-year-old female admitted with signs of fever, nausea, and headache.

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Review of atypical optic neuritis.

Neurol Sci

December 2024

Institute of Medical Biochemistry, Scientific Research Department, University Clinical Center of Serbia, Belgrade, 11000, Serbia.

Optic neuritis (ON), an inflammatory optic neuropathy, is among the most common causes of visual loss. In its initial clinical appearance, ON may have unilateral or bilateral presentation, and anterior (papillitis) or retrobulbar localization. Traditionally, cases are divided into typical and atypical ON.

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Background: In STREAM-1 (Strategic Reperfusion Early After Myocardial Infarction), excess intracranial hemorrhage occurred in patients aged ≥75 years receiving full-dose tenecteplase as part of a pharmaco-invasive strategy, whereas no further intracranial hemorrhage occurred after halving the tenecteplase dose. In STREAM-2 (Second Strategic Reperfusion Early After Myocardial Infarction), half-dose tenecteplase was an effective and safe pharmaco-invasive strategy in older patients with ST-segment-elevation myocardial infarction presenting within <3 hours, compared with primary percutaneous coronary intervention (PCI). We prespecified evaluating the efficacy and safety of a half-dose versus full-dose pharmaco-invasive strategy and compared the half-dose pharmaco-invasive strategy to primary PCI in patients aged ≥75 years.

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The thyroid gland has an important influence on the heart. Long-term exposure to high levels of thyroid hormones may lead to cardiac hypertrophy and dysfunction. The aim of the study was to evaluate the morphological and functional changes in the left ventricle in patients with hyperthyroidism caused by Graves' disease (GD) in comparison with healthy individuals, as well as to investigate potential differences in these parameters in GD patients in relation to the presence of orbitopathy.

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SoutheAsTern eUrope microciRculATION (SATURATION) registry - Design and rationale.

Cardiovasc Revasc Med

December 2024

Institute for Cardiovascular Diseases "Dedinje", Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia. Electronic address:

Background: A considerable number of symptomatic patients leave the cardiac catheterization lab without a definitive diagnosis for their symptoms because no epicardial stenoses are found. The significance of disorders of coronary microvasculature and vasomotion as the cause of symptoms and signs of ischemia has only recently been appreciated. Today we have a wide spectrum of invasive coronary physiology tools but little is known about when and how these tools are used in clinical practice.

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Background Context: Spondylodiscitis management presents significant clinical challenges, particularly in critically ill patients, where the risks and benefits of surgical intervention must be carefully balanced. The optimal timing of surgery in this context remains a subject of debate.

Purpose: This study aims to evaluate the effectiveness of early surgery versus delayed surgery or conservative management in critically ill patients with de novo pyogenic spondylodiscitis.

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This study analyzed the spectral response of EBT3, EBT4, and EBT-XD radiochromic films using absorption spectroscopy. The primary focus was on characterizing the evolution of spectral signatures across a range of absorbed doses, thereby elucidating the unique dose-dependent response profiles of each film type. Ten samples of each film type were subjected to open field irradiation within their designated dose ranges (1-20 Gy for EBT3 and EBT4, 1-50 Gy for EBT-XD).

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Introduction: This study, part of a series, analyses the Swiss cohort from an EBO survey on cataract surgery training in Europe, focusing on Switzerland's unique program. The survey identifies two models: training all residents in surgery, and a "high-volume surgeon" model where only some learn CS post-residency.

Methods: This study analyses the survey results of Swiss participants in the EBO examinations (2018-2022) and compared them with the most important cohorts (Germany, France and Spain).

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Purpose: To investigate the current thoughts and perspectives on kidney stone analysis amongst urologists and urology residents worldwide.

Methods: In October 2022 an online survey supported by the EULIS was circulated amongst urologists and urology residents worldwide. The survey was based on the current EAU guidelines regarding stone analysis and its role in urolithiasis management.

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Background: In this review article, we aimed to discuss the pathogenesis of sensorineural hearing loss (SNHL) in patients with different forms of chronic rhinosinusitis (CRS), with special reference to the connection of the immune response of the nasal and middle ear mucosa and inner ear structures.

Methods: Articles for this review were identified using PubMed and Google© Scholar databases.

Results: Different phenotypes of CRS may be associated with impaired function of the inner and outer cells of the organ of Corti.

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Airway management in patients with advanced ankylosing spondylitis (AS) presents a unique challenge due to possible cervical spine deformities that restrict neck mobility and affect access to the airway. Traditional airway management strategies, such as direct laryngoscopy and even fiberoptic intubation, are often rendered ineffective due to these anatomical limitations. Furthermore, surgical options like tracheostomy can be infeasible in cases with significant neck deformities, necessitating alternative approaches.

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Background: Current guidelines recommend a strategy of clinical surveillance (CS) for patients with asymptomatic severe aortic stenosis (AS) and a normal left ventricular ejection fraction.

Objectives: The aim of this study was to conduct a study-level meta-analysis of randomized controlled trials (RCTs) evaluating the effect of early aortic valve replacement (AVR) compared with CS in patients with asymptomatic severe AS.

Methods: Studies were quantitatively assessed in a meta-analysis using random-effects modeling.

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A rare case of incarcerated obturator hernia in an elderly female: Importance of timely diagnosis and choice of surgical intervention - open or laparoscopic.

Pak J Med Sci

December 2024

Zlatibor Loncar, MD, PhD, Associate Professor of Surgery, Medical Faculty, University of Belgrade; Clinic for Emergency Surgery, Emergency Center, University Clinical Center of Serbia, Belgrade, Serbia.

Article Synopsis
  • - Obturator hernia is a rare condition typically seen in elderly patients, making its diagnosis tricky and raising risks of serious complications like morbidity and mortality.
  • - A case study of an 83-year-old woman revealed that early diagnosis using CT and emergency surgery were crucial to prevent severe issues like bowel necrosis, emphasizing the need for prompt intervention.
  • - The discussion highlights the comparison of surgical methods (open vs. laparoscopic) for hernia repair, stressing that individual patient conditions should guide the choice of technique, while also suggesting further research to better understand the long-term outcomes of each approach.
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Endoscopic retrograde cholangiopancreatography training conditions, results from a pan-European survey: Between vision and reality.

United European Gastroenterol J

November 2024

Junge Gastroenterologie (JuGa) - German Young Gastroenterology Study Group of the DGVS - German Society for Digestive and Metabolic Diseases, Berlin, Germany.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) still has a relatively high complication rate, underscoring the importance of high-quality training. Despite existing guidelines, real-world data on training conditions remain limited. This pan-European survey aims to systematically explore the perceptions surrounding ERCP training.

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Article Synopsis
  • Radical prostatectomy (RP) can lead to stress urinary incontinence post-surgery, but techniques like preserving neurovascular bundles and performing posterior reconstruction can improve recovery.
  • A study at the University Clinical Center of Serbia involved 192 patients and tracked their continence recovery at various intervals up to 24 months, measuring how many pads they used daily.
  • Results showed that patients with urethral suspension and those retaining neurovascular bundles had significantly higher continence rates compared to those without these techniques, with urethral suspension being the most impactful factor for a successful recovery.
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Article Synopsis
  • Forceps delivery is increasingly overlooked in favor of cesarean sections, despite cesarean complications, with concerns primarily focused on safety and long-term effects on children.
  • A study involving 49 women in Serbia assessed the neurological outcomes of children born via forceps at age 7, showing a 16.3% incidence of pathological neurological status among newborns.
  • Long-term issues were found in 6.4% of cases, highlighting that while forceps delivery is generally safe for neurological development, there are still mild disorders that can arise.
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Marburg virus disease outbreak in Rwanda, 2024.

Clin Microbiol Infect

November 2024

Emerging Infections Subcommittee, European Society of Clinical Microbiology and Infectious Disease, Switzerland; High-Level Isolation Unit, Infectious Diseases Unit, La Paz University Hospital, IdiPAZ, CIBERINFEC, Madrid, Spain.

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Radiofrequency ablation (RFA) is effective treatment for Barrett's esophagus (BE). Product of successful RFA is neosquamous epithelium (NSE), which resembles native squamous epithelium and has lower risk for neoplastic transformation. Dilated intercellular spaces (IS) are common microscopic feature of reflux induced injury of esophagus.

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