38 results match your criteria: "University Centre for Dental Medicine[Affiliation]"

Occlusal outcome of orthodontic treatment: a systematic review with meta-analyses of randomized trials.

Eur J Orthod

December 2024

Department of Orthodontics, Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, P.O. Box 1072 Blindern, N-0316 Oslo, Norway.

Background: Several appliances or treatment protocols are marketed to either patients or orthodontists as being associated with improved orthodontic outcomes. However, clinical decision-making should be based on robust scientific evidence and not marketing claims or anecdotal evidence.

Objective: To identify appliances/protocols being associated with improved outcomes of fixed appliance treatment.

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Comparison of clinical parameters of peri-implantitis and parameters related to tissue macrophage sensitization on TiO.

Clin Oral Investig

August 2024

Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.

Objective: Dental implants show impressive survival and like rates, but peri-implantitis is a frequent inflammatory disease which affects the implant-surrounding tissues. While biofilms on the implant surface is considered its etiologic reason, several risk factors determine the pace of progression of peri-implant bone loss. Some risk factors are generally accepted while others are still unconfirmed and a matter of ongoing discussion.

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Oral Candida carriage and resistance against common antifungal agents in hematopoietic stem cell transplantation recipients.

Support Care Cancer

February 2024

Department for Oral Health & Medicine, UZB University Centre for Dental Medicine Basel, University of Basel, Basel, Switzerland.

Purpose: Allogeneic hematopoietic stem cell transplant (HSCT) recipients receiving long-term and high-dose immunosuppressive medications suffer commonly from oral candida infections. This prospective cohort study examined oral fungal carriage in HSCT recipients and screened the susceptibility against commonly used antifungal agents. An increasing oral occurrence of Candida spp.

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Impact of treatment of rheumatoid arthritis on periodontal disease: A review.

Mol Oral Microbiol

August 2024

Department of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine, University of Basel, Basel, Switzerland.

Background: Numerous studies support a bidirectional association between rheumatoid arthritis (RA), a chronic autoimmune degenerative inflammatory joint disease, and periodontitis, a chronic inflammatory disease caused by the immune reaction to bacteria organized in biofilms. RA and periodontitis are both multifactorial chronic inflammatory diseases that share common modifiable and non-modifiable risk factors. There is no cure for RA; treatment is based on lifestyle modifications and a variety of medications: nonsteroidal anti-inflammatory drugs (NSAID), glucocorticoids, and disease-modifying antirheumatic drugs (DMARDs, e.

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The study aimed to summarize current knowledge regarding the use of orthopaedic functional appliances (OFA) in managing unilateral craniofacial microsomia (UCM). The eligibility criteria for the review were (1) assessing use of OFA as a stand-alone treatment and (2) using OFA in combination during or after MDO. The PICO (population, intervention, comparison and outcome) format formulated clinical questions with defined inclusion and exclusion criteria.

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Artificial intelligence and personalised dental medicine - just a hype or true game changers?

Br Dent J

May 2023

Professor and Chair of the Department of Oral Health and Medicine; and Head of Research at the University Centre for Dental Medicine Basel (UZB), University of Basel, Switzerland.

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Previous systematic reviews have reported that coronally advanced flap (CAF) + connective tissue graft (CTG) are the gold standard in root coverage procedures (RCP). Nevertheless, adjunctive treatment with hyaluronic acid (HA) has been proposed to aim at improving clinical outcomes and reducing patient morbidity. The aim of this systematic review and meta-analysis is to compare the use of HA as an adjunctive treatment to CAF procedures in Miller class I and II (recession type 1; RT1) gingival recession (GR) defects treatment with no adjunctive/other treatments.

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Oral active matrix metalloproteinase-8 immunotest may be less accurate in haemato-oncologic patients.

Oral Dis

March 2024

Department for Oral Health & Medicine, UZB University Centre for Dental Medicine Basel UZB, University of Basel, Basel, Switzerland.

Article Synopsis
  • * The research included dental exams for 143 adult patients, revealing that many had acute or chronic infections and periodontitis, with only 13.3% testing positive for aMMP-8.
  • * The findings suggest that the aMMP-8 test may not be very reliable in assessing periodontitis in patients with hematologic diseases, as those with positive results had more oral health issues. *
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Systematic review and meta-analysis of diagnostic studies of proximal surface caries.

Clin Oral Investig

November 2021

Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University Munich, Munich, Germany.

Aim: This systematic review and meta-analysis aimed to assess the diagnostic accuracy and reliability of commonly used caries detection methods for proximal caries diagnostics. Visual examination (VE), bitewing radiography (BWR), laser fluorescence (LF), and fibre-optic transillumination (FOTI) were considered in detail.

Material And Methods: PRISMA guidelines for the reporting of systematic reviews and meta-analyses were applied.

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Human leukocyte antigens are associated with salivary level of active MMP-8.

Clin Exp Dent Res

October 2021

Department for Oral Health and Medicine and Center of Salivary Diagnostics and Hyposalivation, UZB University Centre for Dental Medicine Basel, University of Basel, Basel, Switzerland.

Objectives: This case control study examined the associations of HLA antigens and periodontitis with the salivary level of active MMP-8 (aMMP-8).

Materials And Methods: A total of 202 subjects, registered as Swiss bone marrow donors, participated in the study. HLA-A, -B, and -C types were determined by serology or PCR.

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Systematic review and meta-analysis of diagnostic methods for occlusal surface caries.

Clin Oral Investig

August 2021

Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilian University, Munich, Germany.

Aim: This systematic review and meta-analysis aimed to assess the diagnostic performance of commonly used methods for occlusal caries diagnostics, such as visual examination (VE), bitewing radiography (BW) and laser fluorescence (LF), in relation to their ability to detect (dentin) caries under clinical and laboratory conditions.

Materials And Methods: A systematic search of the literature was performed to identify studies meeting the inclusion criteria using the PIRDS concept (N = 1090). A risk of bias (RoB) assessment tool was used for quality evaluation.

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The purpose of this study was to investigate the ability of dentists to remove composite fillings from endodontic access cavities using illumination from a conventional light source (CLS) versus the fluorescence-aided identification technique (FIT) in terms of completeness, selectivity and treatment duration. Therefore, two independent operators removed composite resin from six sets of root-filled incisors in a maxillary model under simulated clinical conditions using the CLS or FIT method (twelve teeth per operator and technique). The duration of treatment was recorded and before-after micro-CT scans were superimposed for volumetric assessment of treatment completeness and selectivity.

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Guided endodontic treatment of multiple teeth with dentin dysplasia: a case report.

Head Face Med

November 2020

Department of Conservative Dentistry and Periodontology and Center of Dental Traumatology, University Hospital of Würzburg, Würzburg, Pleicherwall 2, 97070, Würzburg, Germany.

Background: To report the outcome of guided endodontic treatment (GET) of a case of dentin dysplasia with pulp canal calcification (PCC) and apical periodontitis based on the use of a 3D-printed template designed by merging cone-beam computed tomography (CBCT) and surface scan data.

Case Presentation: A 12-year old female with radicular dentin dysplasia type I (DD-1) presented for endodontic treatment. Radiography revealed PCC in all teeth and apical radiolucency in seven teeth (12, 15, 26, 31, 32, 36 and 46).

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The aim of this systematic review was to compare the combination of amoxicillin and metronidazole or azithromycin when used as adjunct systemic antibiotics during the non-surgical periodontal therapy of chronic periodontitis. The databases Medline, Embase, Cochrane and Biosis were electronically searched. Additionally, a hand search was conducted up to24 October 2019.

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Awareness and practice of 2D and 3D diagnostic imaging among dentists in Hong Kong.

Br Dent J

May 2020

Oral and Maxillofacial Radiology, Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, University of Hong Kong, Hong Kong SAR, China; Department of Oral Health & Medicine, University Centre for Dental Medicine Basel UZB, University of Basel, Basel, Switzerland.

Aims To investigate the awareness and practice of 2D and 3D diagnostic imaging, including respective equipment, specifications, number of images acquired, indications for CBCT scans, preference between 2D and 3D imaging, and the confidence in acquiring and interpreting radiographic images among dentists in Hong Kong.Materials and methods A citywide survey was performed with an online questionnaire that was sent via the local dental association to registered dentists in Hong Kong. The anonymous survey focused on: their dental background; number, type and age of their intra-oral, panoramic devices; CBCT indications, field-of-view and consideration of low-dose protocols; and their confidence in taking and interpreting these images.

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Impact of CBCT image quality on the confidence of furcation measurements.

J Clin Periodontol

July 2020

Department of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine, University of Basel, Basel, Switzerland.

Background: To investigate the impact of scanning parameter in cone-beam computed tomography (CBCT) images on accuracy and confidence with measurements of furcation involvement (FI) in maxillary molars.

Material And Methods: Six half cadaver heads with present maxillary molars (n = 10) were available. CBCT scans with the fixed-parameter field of view (4 × 4 cm, 12 × 17 cm) amperage and voltage (4 mA, 90 kV) and with varying scan modes (SM), that is images/scan (IS), voxel sizes (VZ) and rotation (R), were performed using one CBCT apparatus.

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Introduction: Haematopoietic stem cell transplantation (HSCT) recipients are at increased risk for severe infections. This study examined the associations of common oral infections with survival and infectious complications in HSCT recipients.

Materials And Methods: All autologous and allogeneic HSCT recipients transplanted in the University Hospital of Basel, Switzerland, between 2008 and 2016 and referred to oral infection control pre-HSCT were included in this retrospective case-control study.

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Animal Experiments in Periodontal and Peri-Implant Research: Are There Any Changes?

Dent J (Basel)

May 2019

Department of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine, University of Basel, Hebelstrasse 3, 4056 Basel, Switzerland.

Animal experiments are a source of debate. This bibliometric study aims to identify published research in two representative dental journals: the Journal of Periodontology (JP) and the Journal of Clinical Periodontology (JCP). Two time points (1982/83 and 2012/13) covering 30 years were chosen.

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Case report A case of a 59-year-old female patient who attended with a history of periodontitis, who had been successfully treated and maintained for several years, is described. Following a full periodontal assessment, the patient was diagnosed with 'generalised periodontitis; stage IV; grade C; currently stable'.Conclusion The present case report exemplifies the use of the 2017 classification system in a successfully treated and well-maintained patient whose treatment need is supportive periodontal treatment.

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Introduction: The aim of this in vitro study was to compare endodontic access cavities in teeth with calcified root canals prepared with the conventional technique and a guided endodontics approach regarding the detection of root canals, substance loss, and treatment duration.

Methods: Six identical sets of upper and lower jaw models were produced with 3-dimensional-printed incisors that had simulated calcified root canals. Splints for guided access preparations were fabricated based on 3-dimensional surface scans and cone-beam computed tomographic data sets.

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This case report is the fourth in a series that illustrates the application of the BSP implementation plan for diagnosing periodontitis patients according to the 2017 classification. It demonstrates the diagnostic approach and disease classification for a previously treated patient who presented with a diagnosis of unstable generalised periodontitis; stage IV, grade C. We describe a case of a 49-year-old patient who attended with a history of periodontal treatment over several years.

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The objective of this case report is to illustrate the diagnosis and classification of periodontitis, according to the 2017 classification system, as recommended in the British Society of Periodontology (BSP) implementation plan. A 37-year-old female was diagnosed with periodontitis (molar-incisor pattern), stage III, grade C, currently unstable. Several issues pertinent to the diagnosis of localised forms of periodontitis in young patients are discussed in relation to the current and previous classification systems.

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The objective of this case report is to illustrate the diagnosis and classification of periodontitis according to the 2017 classification system as recommended in the British Society of Periodontology (BSP) implementation plan. We describe a case of a patient who was diagnosed with 'localised periodontitis; stage II, grade B; currently unstable'. The present case report presents an example for the application of the new classification system and illustrates how the new classification system captures disease severity, extent and disease susceptibility by staging and grading periodontitis.

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Comparing the Antimicrobial In Vitro Efficacy of Amoxicillin/Metronidazole against Azithromycin-A Systematic Review.

Dent J (Basel)

October 2018

Clinic of Preventive Dentistry, Periodontology and Cariology, Center of Dental Medicine, University of Zurich, CH-8032 Zurich, Switzerland.

On account of its proven clinical efficacy, the combination of systemically administered amoxicillin and metronidazole is frequently adjuncted to non-operative periodontal therapy and well documented. Potential drawbacks of this regimen, e.g.

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