1 results match your criteria: "University Center for Biological and Farming Sciences[Affiliation]"
High frequency of MLH1 promoter methylation mediated by gender and age in colorectal tumors from Mexican patients.
Gac Med Mex
February 2022
Department of Cellular and Molecular Biology, University Center for Biological and Farming Sciences, Universidad de Guadalajara. Jalisco, Mexico.
Introduction: Several genes determine the development of colorectal cancer (CRC), such as MLH1, which encodes a protein that participates in DNA repair. MLH1 hypermethylation has been associated with gene silencing.
Objective: To analyze the methylation of five regions of MLH1 CpG island in colorectal tumors from Mexican patients.