383 results match your criteria: "University Católica Dom Bosco[Affiliation]"

Long-term Outcomes of Geriatric Medicine Teaching Strategies: Comparing no Content, Traditional Lecture, and Flipped Classroom 2 Years Postintervention.

Med Sci Educ

December 2024

Department of Medical Education and Division of Geriatric Medicine, School of Medicine, Federal University of Juiz de Fora, Av. Eugênio do Nascimento S/nº, Bairro: Dom Bosco - CEP.:36038-330, Juiz de Fora, Minas Gerais Brazil.

Article Synopsis
  • The study investigates the long-term effects of flipped classrooms (FL) and traditional lectures (TR) on medical students' attitudes and knowledge about geriatrics.
  • The research involved 216 medical students and measured their attitudes, empathy, knowledge, and stereotypes toward older adults over two years following different educational approaches.
  • Results showed that students in the flipped classroom scored better in knowledge and attitudes compared to traditional lecture students and a control group with no exposure, suggesting that teaching methods can significantly influence lasting perceptions of geriatrics in future physicians.
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Characterization of a novel acidic phospholipase A isolated from the venom of Bothrops mattogrossensis: From purification to structural modeling.

Int J Biol Macromol

December 2024

Laboratory of Cellular Immunology Applied to Health, Oswaldo Cruz Foundation, FIOCRUZ Rondônia, Porto Velho, RO, Brazil; Department of Medicine, Federal University of Rondonia (UNIR), Porto Velho, RO, Brazil. Electronic address:

Phospholipases A (PLAs) are highly prevalent in Bothrops snake venom and play a crucial role in inflammatory responses and immune cell activation during envenomation. Despite their significance, the specific role of PLAs from Bothrops mattogrossensis venom (BmV) in inflammation is not fully understood. This study sought to isolate and characterize a novel acidic PLA from BmV, designated BmPLA-A, and to evaluate its effects on human umbilical vein endothelial cells (HUVECs), with a specific focus on cytotoxicity, adhesion, and detachment.

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Introduction: This study aimed to investigate the association between the 2023 Beers criteria for inappropriate prescribing and different health outcomes among community-dwelling older individuals after a 1-year follow-up period and to assess the use and factors associated with inappropriate prescribing.

Methods: This longitudinal population study spanning from 2017 to 2018 included 490 community-dwelling older adults (≥60 years old) receiving care from family medicine teams in the city of São João del-Rei, Brazil. The 2023 Beers criteria was used to identify potentially inappropriate medications (PIMs).

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Improving serum redox balance, inflammatory status, physical function, and cognitive ability through dual-task resistance training and detraining in nursing home residents.

Exp Gerontol

December 2024

Postgraduate Program in Physical Education, Federal University of Mato Grosso, Cuiabá, MT, Brazil; Center for Proteomic and Biochemical Analysis, Postgraduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasília, Brasília, Brazil. Electronic address:

Objective: This study investigated the effects of dual-task resistance training (RT) and detraining on physical function, cognitive capacity, lipid profile, renal function, oxidative stress markers, and chronic inflammation of institutionalized older adults.

Methods: The study involved 11 older adults (83.09 ± 8.

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Background: The increasing industrialization and hydrocarbon use have led to concerning soil contamination. Oil spills and improper disposal of oily waste pose threats to ecosystems and human health. The recovery of these environments is essential, but separating oily components from soil remains challenging.

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Plant-Based Diet and Sports Performance.

ACS Omega

December 2024

S-Inova Biotech Postgraduate in Biotechnology, Catholic University Dom Bosco (UCDB), Campo Grande 79117-900, Brazil.

Recently, interest in plant-based diets has grown significantly, driven by health and environmental concerns. Plant-based diets offer potential health benefits, including decreased risk of cardiovascular disease, weight management, and blood glucose regulation. This diet profile is rich in complex carbohydrates, antioxidants, dietary fiber, and phytochemicals.

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Article Synopsis
  • - The study investigates how climate variables affect frog communities in urban ecosystems in Brazil, focusing on species richness, abundance, and temporal dynamics over three years.
  • - Researchers used statistical models and various methods to analyze seasonality and biodiversity, finding that species richness remained relatively stable, while species abundance fluctuated more due to factors like humidity and temperature.
  • - The results suggest that frog species composition in peri-urban areas tends to remain consistent over time, even amidst climate variations, which provides insights into species coexistence mechanisms and the effects of urbanization on biodiversity.
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Objectives: This study aimed to investigate the impact of organic, conventional, and stingless honey on gummy candies, focusing on the effect of the cariogenic bacterium, Streptococcus mutans UA159, and total bacterial count in saliva from adolescents.

Methods: Antimicrobial compounds in three honey samples were identified, and the minimum inhibitory concentration against S. mutans UA159 was determined.

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Discovery of Five Classes of Bacterial Defensins: Ancestral Precursors of Defensins from Eukarya?

ACS Omega

November 2024

S-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117900, Brazil.

Article Synopsis
  • - Defensins are found in various organisms and categorized into - and -defensins; recent studies have identified 74 new -defensins in bacteria and propose a new classification system for them.
  • - The study presents the first NMR structure of a defensin known as Xanthusin-1, suggesting it may represent a unique group of defensins, with gene expression observed in specific growth media.
  • - Findings indicate a broader distribution of defensins beyond eukaryotes, hinting at a prokaryotic origin for certain motifs, and show that both Gram-positive and Gram-negative bacteria possess defensins, indicating early evolutionary roots but also significant gene loss.
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Emerging peptide-based technology for biofilm control.

Expert Opin Biol Ther

December 2024

Centro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília, Brazil.

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Computational Approaches for Antimicrobial Peptide Delivery.

Bioconjug Chem

December 2024

S-Inova Biotech, Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, Mato Grosso do Sul 70990-160, Brazil.

Article Synopsis
  • Peptides are being explored as alternative treatments for various infections, but their effectiveness is limited by issues like instability and toxicity to healthy cells.
  • New administration methods, particularly using nanoparticles as carriers, show promise for improving peptide delivery, though current design efforts are time-consuming and often based on trial and error.
  • Recent advancements in computational approaches aim to speed up the creation of efficient drug delivery systems for peptides, increasing the potential for optimized drug development.
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Cm-p5, a molluscan-derived antifungal peptide exerts its activity by a membrane surface covering in a non-penetrating mode.

Peptides

December 2024

Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México (ICF-UNAM), Av. Universidad S/N, Chamilpa, Cuernavaca, Morelos 62210, México. Electronic address:

Amidst the health crisis caused by the rise of multi-resistant pathogenic microorganisms, Antimicrobial Peptides (AMPs) have emerged as a potential alternative to traditional antibiotics. In this sense, Cm-p5 is an AMP with fungistatic activity against the yeast Candida albicans. Its antimicrobial activity and selectivity have been well characterized; however, the mechanism of action is still unknown.

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Quality and stability of meat products prepared with chicken fillets affected by white striping myopathy.

J Food Sci Technol

November 2024

Department of Food Science and Technology, State University of Londrina (UEL), Rodovia Celso Garcia Cid, PR-445, Km 380, Postal Box 10.011, Londrina, Paraná 86057-970 Brazil.

This study aimed to evaluate the quality and oxidative stability of chicken burger and mortadella prepared with fillets affected by white striping (WS) myopathy as compared with products prepared with normal fillets (control) There were no differences in pH, L*, or b* between treatments (WS vs. control); however, water holding capacity was higher in control burgers and mortadellas. In burgers, the use of WS fillet led to an increase in lipid content and a reduction in moisture content.

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Purpose: The aim of this study was to investigate the impact of malocclusion and oral habits on oral health-related quality of life and sleep disturbance in young adults.

Methods: A cross-sectional study was conducted with a sample of 213 young adults aged 18-30 years. Dental occlusion data were assessed through clinical examination.

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This study examines the kinetics and thermodynamics of the inclusion complex (IC) formation between sodium dodecylbenzenesulfonate (SDBS) and amine-modified β-cyclodextrin (βCD-NH) using surface plasmon resonance (SPR) and theoretical analysis. We determined a binding constant of 10 L mol for the thermodynamically stable complex ([βCD-NH/SDBS]°) within the temperature range of 285.2-301.

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Smart indoor tourist attractions, such as smart museums and aquariums, require a significant investment in indoor localization devices. The use of Global Positioning Systems on smartphones is unsuitable for scenarios where dense materials such as concrete and metal blocks weaken GPS signals, which is most often the case in indoor tourist attractions. With the help of deep learning, indoor localization can be done region by region using smartphone images.

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Detection of Brucella S19 Vaccine Strain DNA in Domestic and Wild Ungulates from Brazilian Pantanal.

Curr Microbiol

August 2024

Post-Graduate Program in Environmental Sciences and Agricultural Sustainability, Dom Bosco Catholic University (UCDB), Av. Tamandaré, 6000, Jardim Seminário, Campo Grande, Mato Grosso Do Sul, 79117-900, Brazil.

The Pantanal region, the largest floodplain in the world, has a huge biodiversity and is an important livestock center. Bovine brucellosis has been reported in the region over the last three decades, posing implications for cattle industry as well as for the maintenance of biodiversity. We aimed to investigate the presence of B.

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This article investigates the intersection between innovation, Health 4.0, and financial management in the healthcare industry, emphasizing the importance of operational efficiency and quality of care. The study aims to analyze how financial management processes in healthcare relate to Health 4.

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Discontinuation of HIIT restores diabesity while retraining increases gut microbiota diversity.

iScience

August 2024

Center for Proteomics and Biochemical Analysis, Postgraduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasília, Brasília, DF, Brazil.

Investigations involving high-intensity interval training (HIIT) have proven to be efficient in controlling diabesity. This study aimed to assess the impact of discontinuing HIIT and retraining within the context of diabesity. 75 C57BL6 mice went through 5 stages: baseline, induction of diabesity with Western diet, training, detraining, and retraining (6 weeks each period).

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Backgound: During the SARS-CoV-2 pandemic, a significant number of critical patients required ventilatory assistance in health institutions. In this context, Ventilator-Associated Pneumonia (VAP) was the most prevalent nosocomial infection among critically ill patients. We aimed to analyze the occurrence of VAP in critically ill patients with SARS-CoV-2 and the risk factors associated with the outcome.

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CRISPR/Cas genome editing in soybean: challenges and new insights to overcome existing bottlenecks.

J Adv Res

August 2024

Embrapa Genetic Resources and Biotechnology, Brasília, DF, Brazil; Bioprocess Engineering and Biotechnology Graduate Program, Federal University of Paraná (UFPR), Curitiba, PR, Brazil; National Institute of Science and Technology, INCT PlantStress Biotech, EMBRAPA, Brasília, DF, Brazil; Catholic University of Brasília, Graduate Program in Genomic Sciences and Biotechnology, Brasília, DF, Brazil; Catholic University Dom Bosco, Graduate Program in Biotechnology, Campo Grande, MS, Brazil. Electronic address:

Background: Soybean is a worldwide-cultivated crop due to its applications in the food, feed, and biodiesel industries. Genome editing in soybean began with ZFN and TALEN technologies; however, CRISPR/Cas has emerged and shortly became the preferable approach for soybean genome manipulation since it is more precise, easy to handle, and cost-effective. Recent reports have focused on the conventional Cas9 nuclease, Cas9 nickase (nCas9) derived base editors, and Cas12a (formally Cpf1) as the most commonly used genome editors in soybean.

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Effects of physical exercise on Akkermansia muciniphila: a systematic review of human and animal studies.

Benef Microbes

August 2024

Center for Proteomic and Biochemical Analysis, Postgraduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasília, Brasília, Brazil, 28106Catholic University of Brası́lia, Brası́lia, Brazil.

This systematic review aimed to compile various research designs, including experimental, longitudinal, cross-sectional, and case studies in humans and experimental studies in rodents, to examine changes in Akkermansia muciniphila abundance in response to exercise. This comprehensive approach can improve our understanding of A. muciniphila response to physical exercise and highlight gaps in the literature, providing valuable insights for future microbiome research.

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Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence.

Biochim Biophys Acta Gen Subj

November 2024

S-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117900, Brazil; Programa de Pós-Graduação em Ciências Ambientais e Sustentabilidade Agropecuária, Universidade Católica Dom Bosco, Campo Grande 79117900, Brazil. Electronic address:

Background: Resistant infectious diseases caused by gram-negative bacteria are among the most serious worldwide health problems. Antimicrobial peptides (AMPs) have been explored as promising antibacterial, antibiofilm, and anti-infective candidates to address these health challenges.

Major Conclusions: Here we report the potent antibacterial effect of the peptide PaDBS1R6 on clinical bacterial isolates and identify an immunomodulatory peptide fragment incorporated within it.

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Quality of life of patients after kidney transplant: ADHERE Brazil multicenter cross-sectional study.

Appl Nurs Res

August 2024

Renal Transplantation Unit, University Hospital, Federal University of Juiz de Fora, Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil; Interdisciplinary Center for Studies and Research in Nephrology (NIEPEN), Faculty of Medicine, Federal University of Juiz de Fora. Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil. Electronic address:

Background: Quality of life (QoL) is a measure to evaluate kidney transplant (KT) results.

Aim: To describe the QoL profile in a larger sample of Brazilian patients who underwent KT according to age, sex, and access to KT.

Methods: We conducted a secondary data analysis of the ADHERE BRAZIL multicenter cross-sectional study including 1105 patients from 20 centers, considering KT access region and transplant activity.

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