4 results match your criteria: "University Campus of Voutes[Affiliation]"

Impact of comorbidities on patient-reported outcomes in psoriatic arthritis: the case of endometriosis.

Rheumatol Int

September 2024

Section of Molecular Pathology and Human Genetics, Department of Internal Medicine, School of Medicine, University of Crete, University Campus of Voutes, Heraklion, 71003, Greece.

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Remnant cholesterol in atherosclerotic cardiovascular disease: A systematic review and meta-analysis.

Hellenic J Cardiol

November 2023

Department of Clinical Therapeutics, National and Kapodistrian University of Athens Medical School, Athens, Greece; Biosciences Institute, Vascular Biology and Medicine Theme, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK. Electronic address:

Article Synopsis
  • - The study investigates how remnant cholesterol (RC) levels relate to the risk of developing or relapsing atherosclerotic cardiovascular disease (ASCVD), finding that higher RC levels correlate with increased cardiovascular risks in both patients with and without pre-existing conditions.
  • - Analyzing data from 29 studies involving over 257,000 participants, the findings reveal that directly measured RC levels more strongly predict the risk of major adverse cardiac events (MACE) than calculated levels.
  • - While lipid-lowering therapies (LLTs) can lower RC levels, the clinical significance of this reduction in relation to ASCVD risk still requires further research to understand its impact.
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Aims: The clinical value of carotid atherosclerosis markers for residual risk stratification in high atherosclerotic cardiovascular disease (ASCVD) risk patients is not established. We aimed to derive and validate optimal values of markers of carotid subclinical atherosclerosis improving risk stratification in guidelines-defined high ASCVD risk patients.

Methods And Results: We consecutively analysed high or very high ASCVD risk patients from a cardiovascular (CV) prevention registry (n = 751, derivation cohort) and from the Atherosclerosis Risk in Communities (ARIC) study (n = 2,897, validation cohort).

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