5,291 results match your criteria: "University Berlin[Affiliation]"

Background: Snapping scapula syndrome (SSS) is a rare condition that is oftentimes debilitating. For patients whose symptoms are resistant to nonoperative treatment, arthroscopic surgery may offer relief. Because of the rarity of SSS, reports of clinical outcomes after arthroscopic SSS surgery are primarily limited to small case series and short-term follow-up studies.

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Scale-Up of PTFE-Based Gas Diffusion Electrodes Using an Electrolyte-Integrated Polymer-Coated Current Collector Approach.

ACS Energy Lett

April 2024

The Electrochemical Energy, Catalysis, and Materials Science Laboratory, Department of Chemistry, Chemical Engineering Division, Technical University Berlin, 10623 Berlin, Germany.

Nonconductive porous polymer substrates, such as PTFE, have been pivotal in the fabrication of stable and high-performing gas diffusion electrodes (GDEs) for the reduction of CO/CO in small scale electrolyzers; however, the scale-up of polymer-based GDEs without performance penalties to technologically more relevant electrode sizes has remained elusive. This work reports on a new current collector concept that enables the scale-up of PTFE-based GDEs from 5 to 100 cm and beyond. The present approach builds on a multifunctional current collector concept that enables multipoint front-contacting of thin catalyst coatings, which mitigates performance losses even for high resistivity cathodes.

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Both partial inactivation as well as activation of NF-κB signaling lead to hypertension and chronic kidney disease.

Nephrol Dial Transplant

November 2024

International Joint Laboratory for Embryonic Development & Prenatal Medicine, Division of Histology and Embryology, Medical College, Jinan University, Guangzhou, China.

Background: Activation of nuclear factor-kappa B (NF-κB) signalling is key in the pathogenesis of chronic kidney disease (CKD). However, a certain level of NF-κB activity is necessary to enable tissue repair.

Methods: The relationship between activated and inactivated NF-κB signaling and the pathogenesis of CKD was investigated using mouse models of NF-κB partial inactivation (mutating cysteine at position 59 of the sixth exon on the NF-κB gene into alanine) and activation (mutating cysteine at position 59 of the sixth exon on the NF-κB gene into serine).

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Article Synopsis
  • Ablation of atrial fibrillation (AF) has become a widely accepted and effective treatment for managing this common heart rhythm disorder over the last 30 years.
  • Since the initial consensus document in 2007, new research and technologies have significantly changed AF ablation practices, necessitating updates in 2012 and 2017.
  • A new consensus document was recently created by various cardiac societies to provide a current framework for selecting and managing patients for catheter or surgical AF ablation, reflecting the evolving nature of the field.
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Collating the voice of people with autoimmune diseases: Methodology for the Third Phase of the COVAD Studies.

Rheumatol Int

July 2024

Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK.

Article Synopsis
  • The focus on holistic patient care for autoimmune and rheumatic diseases (AIRDs) emphasizes the importance of subjective well-being, social factors, and mental health, alongside traditional measures of disease.
  • The COVAD-3 survey is set up as an extensive online self-report study to assess various lifestyle factors of AIRD patients and healthy individuals, ensuring it's accessible through multiple languages and thorough testing.
  • The goal of COVAD-3 is to understand how social, economic, and psychological factors affect the quality of life in AIRD patients, ultimately aiming to enhance their overall health and treatment approaches.
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The analysis of almost holistic food profiles has developed considerably over the last years. This has also led to larger amounts of data and the ability to obtain more information about health-beneficial and adverse constituents in food than ever before. Especially in the field of proteomics, software is used for evaluation, and these do not provide specific approaches for unique monitoring questions.

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Selenium, diabetes, and their intricate sex-specific relationship.

Trends Endocrinol Metab

September 2024

Institute for Experimental Endocrinology, Max Rubner Center, Charité University Berlin, Germany. Electronic address:

Selenium (Se) is an essential trace element, which is inserted as selenocysteine (Sec) into selenoproteins during biosynthesis, orchestrating their expression and activity. Se is associated with both beneficial and detrimental health effects; deficient supply or uncontrolled supplementation raises concerns. In particular, Se was associated with an increased incidence of type 2 diabetes (T2D) in a secondary analysis of a randomized controlled trial (RCT).

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Paraspinal muscle atrophy is gaining attention in spine surgery due to its link to back pain, spinal degeneration and worse postoperative outcomes. Electrical impedance myography (EIM) is a noninvasive diagnostic tool for muscle quality assessment, primarily utilized for patients with neuromuscular diseases. However, EIM's accuracy for paraspinal muscle assessment remains understudied.

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Background: Growth hormone (GH) resistance is characterized by high GH levels but low levels of insulin-like growth factor-I (IGF-I) and growth hormone binding protein (GHBP) and, for patients with chronic disease, is associated with the development of cachexia.

Objectives: We investigated whether GH resistance is associated with changes in left ventricular (LV) mass (cardiac wasting) in patients with cancer.

Methods: We measured plasma IGF-I, GH, and GHBP in 159 women and 148 men with cancer (83% stage III/IV).

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The self-assembly of spheres into geometric structures, under various theoretical conditions, offers valuable insights into complex self-assembly processes in soft systems. Previous studies have utilized pair potentials between spheres to assemble maximum contact clusters in simulations and experiments. The morphometric approach to solvation free energy that we utilize here goes beyond pair potentials; it is a geometry-based theory that incorporates a weighted combination of geometric measures over the solvent accessible surface for solute configurations in a solvent.

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Sodium all-solid-state batteries may become a novel storage technology overcoming the safety and energy density issues of (liquid-based) sodium ion batteries at low cost and good resource availability. However, compared to liquid electrolyte cells, contact issues and capacity losses due to interface reactions leading to high cell resistance are still a problem in solid-state batteries. In particular, sulfide-based electrolytes, which show very high ionic conductivity and good malleability, exhibit degradation reactions at the interface with electrode materials and carbon additives.

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Surfactin is a cyclic hexalipopeptide compound, nonribosomal synthesized by representatives of the Bacillus subtilis species complex which includes B. subtilis group and its closely related species, such as B. subtilis subsp subtilis, B.

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In the unpredictable Anthropocene, a particularly pressing open question is how certain species invade urban environments. Sex-biased dispersal and learning arguably influence movement ecology, but their joint influence remains unexplored empirically, and might vary by space and time. We assayed reinforcement learning in wild-caught, temporarily captive core-, middle-, or edge-range great-tailed grackles-a bird species undergoing urban-tracking rapid range expansion, led by dispersing males.

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The benefits and disbenefits associated with cultural ecosystem services of urban green spaces.

Sci Total Environ

May 2024

Institute of Geography, Humboldt-University Berlin, Unter den Linden 6, 10099 Berlin, Germany; Department of Computational Landscape Ecology, Helmholtz Centre for Environmental Research - UFZ, 04318 Leipzig, Germany. Electronic address:

Cultural ecosystem services (CES) and disservices shape landscape planning policy to a huge extent. We focus on the benefits and disbenefits associated with CES. The study aimed to explore the co-occurrence of the benefits and disbenefits associated with CES as well as the relationship between spatial and landscape characteristics and specific benefits and disbenefits.

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Quantification of Trimethylamine--Oxide and Trimethylamine in Fish Oils for Human Consumption.

Molecules

March 2024

GALAB Laboratories GmbH, Am Schleusengraben 7, 21029 Hamburg, Germany.

Supplementing fish oil is one of the strategies to reduce the risk of cardiovascular disease, the leading cause of death around the world. Contradictorily, fish oil may also contain trimethylamine--oxide, a recently emerged risk factor for cardiovascular disease, as well as one of its precursors, trimethylamine. A method suitable for routine quantification of trimethylamine--oxide and trimethylamine in fish oil with a quick and easy liquid extraction without derivatization has been developed.

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Current German Recommendations and International Research on the Use of COVID-19 Boosters among Health Care Providers in 2024: A Narrative Review.

Medicina (Kaunas)

February 2024

Department of Oral, Craniomaxillofacial and Plastic Surgery, University Hospital Ruppin-Brandenburg, Faculty of Medicine, Medical University Brandenburg, D-16816 Neuruppin, Germany.

While the World Health Organization (WHO) has de-escalated coronavirus disease 2019 (COVID-19) from a global health emergency, ongoing discussions persist as new viral variants. This article aimed to consolidate German recommendations and international research to offer health care providers (HCPs) a comprehensive guide on COVID-19 boosters in 2024. The review outlines key recommendations from the German Robert Koch Institute.

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Human cognition is incredibly flexible, allowing us to thrive within diverse environments. However, humans also tend to stick to familiar strategies, even when there are better solutions available. How do we exhibit flexibility in some contexts, yet inflexibility in others? The constrained flexibility framework (CFF) proposes that cognitive flexibility is shaped by variability, predictability, and harshness within decision-making environments.

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Collective dynamics emerge from countless individual decisions. Yet, we poorly understand the processes governing dynamically-interacting individuals in human collectives under realistic conditions. We present a naturalistic immersive-reality experiment where groups of participants searched for rewards in different environments, studying how individuals weigh personal and social information and how this shapes individual and collective outcomes.

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Five years after a German study on insect biomass described a multi-decade decline in nature protected habitats, the DINA (Diversity of Insects in Nature protected Areas) project has investigated the status of insects in 21 selected nature reserves across Germany in the years 2020 and 2021. We used the same methods and protocols for trapping and measuring the biomass of flying insects as in the earlier study. Across two vegetation periods, we accumulated a comprehensive data set of 1621 data points of two-week emptying intervals to evaluate the insect biomass along gradients from arable land into nature reserves through transects of Malaise traps.

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It is a central tenet of attachment theory that individual differences in attachment representations organize behavior during social interactions. Secure attachment representations also facilitate behavioral synchrony, a key component of adaptive parent-child interactions. Yet, the dynamic neural processes underlying these interactions and the potential role of attachment representations remain largely unknown.

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Tuning the photophysical properties of iron-based transition-metal complexes is crucial for their employment as photosensitizers in solar energy conversion. For the optimization of these new complexes, a detailed understanding of the excited-state deactivation paths is necessary. Here, we report femtosecond transient mid-IR spectroscopy data on a recently developed octahedral ligand-field enhancing [Fe(dqp)] () complex with dqp = 2,6-diquinolylpyridine and prototypical [Fe(bpy)] ().

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Although sulfurated polymers promise unique properties, their controlled synthesis, particularly when it comes to complex and functional architectures, remains challenging. Here, we show that the copolymerization of oxetane and phenyl isothiocyanate selectively yields polythioimidocarbonates as a new class of sulfur containing polymers, with narrow molecular weight distributions (M=5-80 kg/mol with Đ≤1.2; M=124 kg/mol) and high melting points of up to 181 °C.

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Background: Neglect can be a long-term consequence of chronic stroke that can impede an individual's ability to perform daily activities, but chronic and discrete forms can be difficult to detect. We developed and evaluated the "immersive virtual road-crossing task" (iVRoad) to identify and quantify discrete neglect symptoms in chronic stroke patients.

Method: The iVRoad task requires crossing virtual intersections and placing a letter in a mailbox placed either on the left or right.

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Article Synopsis
  • Scientists are discovering more about small DNA viruses, especially those called porcine circoviruses (PCVs), which are common in pigs and can cause diseases.
  • PCV3, a new type of PCV, has been linked to serious health issues in pigs and can be passed to other animals, like baboons, during organ transplants.
  • Researchers found that some human circoviruses are related to PCV3, which could be a problem for people getting blood transfusions or organ transplants, especially if their immune system is weak.
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