124 results match your criteria: "University Aix Marseille[Affiliation]"
Appl Health Econ Health Policy
June 2017
Aix-Marseille University (Aix-Marseille School of Economics), CNRS & EHESS, GREQAM and IDEP, 2 rue de la Charité, 13236, Marseille Cedex 02, France.
Background: The choice of elicitation format is a crucial but tricky aspect of stated preferences surveys. It affects not only the quantity and quality of the information collected on respondents' willingness to pay (WTP) but also the potential errors/biases that prevent their true WTP from being observed.
Objectives: We propose a new elicitation mechanism, the circular payment card (CPC), and show that it helps overcome the drawbacks of the standard payment card (PC) format.
Eur J Health Econ
December 2016
Département Santé Environnement, Institut de Veille Sanitaire, 12 rue du Val d'Osne, 94415, Saint Maurice Cedex, France.
Public decision-makers commonly use health impact assessments (HIA) to quantify the impacts of various regulation policies. However, standard HIAs do not consider that chronic diseases (CDs) can be both caused and exacerbated by a common factor, and generally focus on exacerbations. As an illustration, exposure to near road traffic-related pollution (NRTP) may affect the onset of CDs, and general ambient or urban background air pollution (BP) may exacerbate these CDs.
View Article and Find Full Text PDFJ Mark Access Health Policy
August 2016
Faculty of Medicine - Public Health department, University Aix-Marseille, Marseille, France.
Objective: Advanced therapy medicinal products (ATMPs) constitute a class of innovative products that encompasses gene therapy, somatic cell therapy, and tissue-engineered products (TEP). There is an increased investment of commercial and non-commercial sponsors in this field and a growing number of ATMPs randomized clinical trials (RCT) and patients enrolled in such trials. RCT generate data to prove the efficacy of a new therapy, but the discontinuation of RCTs wastes scarce resources.
View Article and Find Full Text PDFFront Psychol
August 2016
Univ Lyon, Université Lumière Lyon 2, GATE L-SE UMR 5824 Ecully, France.
Dominance solvability is one of the most straightforward solution concepts in game theory. It is based on two principles: dominance (according to which players always use their dominant strategy) and iterated dominance (according to which players always act as if others apply the principle of dominance). However, existing experimental evidence questions the empirical accuracy of dominance solvability.
View Article and Find Full Text PDFJ Thorac Oncol
October 2016
Respiratory Disease Department, Tenon Hospital APHP, Paris VI University, French Cooperative Thoracic Intergroup, Paris, France.
A shift in mortality and morbidity has been observed in people living with human immunodeficiency virus (PLWHIV) from acquired immunodeficiency syndrome (AIDS) to non-AIDS diseases. Lung cancer has the highest incidence rates among all the non-AIDS-defining malignancies and is associated with mortality rates that exceed those of other cancers. Strategies to increase lung cancer survival in PLWHIV are needed.
View Article and Find Full Text PDFHealth Policy
August 2016
Aix-Marseille University, INSERM, IRD, SESSTIM, 23 rue Stanislas Torrents, 13006 Marseille, France; Aix-Marseille University (Aix-Marseille School of Economics), CNRS & EHESS, 23 rue Stanislas Torrents, 13006 Marseille, France. Electronic address:
Evidence suggests that the effect of health expenditure on health outcomes is highly context-specific and may be driven by other factors. We construct a panel dataset of 18 countries from the Middle East and North Africa region for the period 1995-2012. Panel data models are used to estimate the macro-level determinants of health outcomes.
View Article and Find Full Text PDFMedicine (Baltimore)
June 2016
aNephrology Department, Bocage University Hospital and UMR 1098 bInternal Medicine and Systemic Diseases Department, Bocage University Hospital, Dijon cInternal Medicine Department, Edouard Herriot University Hospital and University Claude Bernard Lyon 1, Lyon dInternal Medicine Department, National Referral Center for Rare Autoimmune and Systemic Diseases, Cochin University Hospital and University Paris Descartes, Paris eNephrology Department, Macon Hospital, Mâcon fNephrology Department, La Conception University Hospital and University Aix-Marseille, Marseille gInternal Medicine Department, Ambroise-Paré University Hospital, Paris hNephrology Department, Maison Blanche University Hospital, Reims iInternal Medicine Department, University Hospital Avicenne and University Sorbonne, Paris jNephrology Department, Tenon University Hospital, Paris kNephrology Department, Brabois University Hospital and INSERM CIC-EC CIE6, Nancy lNephrology Department, Dole Hospital, Dôle mNephrology Department, Ambroise-Paré University Hospital, Boulogne-Billancourt nInternal Medicine and Clinical Immunology Department, Pitié Salpetriere University Hospital and DHU Inflammation, Immunopathology, Biotherapy, Paris VI oInternal Medicine Department, University Hospital Clermont Ferrand, Clermont-Ferrand pInternal Medicine Department, Quinze-Vingts Ophthalmogy Hospital, Paris qNephrology Department, University Hospital, Rennes rNephrology Department, University Hospital Claude Huriez, Lille sRheumatology Department, National Referral Center for Rare Autoimmune Diseases, Strasbourg University Hospital, and UMR 1109, Strasbourg, France.
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease, defined by the association of idiopathic acute TINU. The aim of our work was to determine the characteristics of adult TINU syndrome in France, and to assess factors (including treatment) influencing medium-term prognosis.We conducted a nationwide study including 20 French hospitals.
View Article and Find Full Text PDFThe aim of this work is to encapsulate a self-healing photo-polymerisable material for aerospace applications. To meet the technical requirements of space applications - low and high temperatures: -120 °C (dark side) to +250 °C (solar side); UV radiations: 200-400 nm; low pressure: 10(-4 )Pa - we chose trimethylolpropane triacrylate as healing agent. This monomer polymerises at 190 °C.
View Article and Find Full Text PDFBrain Res Bull
June 2016
Laboratory of Neurobiology, Kazan Federal University, Kazan, Russia; INMED-INSERM U901, Marseille, France; University Aix-Marseille II, Marseille, France.
Soc Sci Med
February 2016
Aix-Marseille University (Aix-Marseille School of Economics), CNRS & EHESS. GREQAM - Centre de la Vieille Charité, 2 Rue de la Charité, 13236, Marseille, Cedex 2, France; ORS PACA, Observatoire Régional de la Santé, Provence Alpes Côte d'Azur. 23 rue Stanislas Torrents, 13006 Marseille, France. Electronic address:
In almost all African countries, informal payments are frequently made when accessing health care. Some literature suggests that the informal payment system could lead to quasi-redistribution among patients, with physicians playing a 'Robin Hood' role, subsidizing the poor at the expense of the rich. We empirically tested this assumption with data from the rounds 3 and 5 of the Afrobarometer surveys conducted in 18 and 33 African countries respectively, from 2005 to 2006 for round 3 and from 2011 to 2013 for round 5.
View Article and Find Full Text PDFTechnol Health Care
January 2017
Department of Bioinformatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
This paper is a contribution on financial sustainability of hospital biobanks and data warehouses for biospecimens. It aims to discuss new venues for cost models in addition to conventional cost recovery models. It follows the first paper issues on economics of biobanking by Huttin and Liebman, where adaptive platforms where already suggested for biobanks in translational medicine.
View Article and Find Full Text PDFJ Visc Surg
February 2016
Department of digestive surgery, Hôpital Nord, university Aix-Marseille, chemin des Bourrely, 13015 Marseille, France.
Econ Hum Biol
May 2016
Centre for Development Economics, Delhi School of Economics, University of Delhi, Delhi 110007, India. Electronic address:
A growing literature indicates that effects of early-life health on adult economic outcomes could be substantial in developing countries, but the magnitude of this effect is debated. We document a robust gradient between the early-life mortality environment to which men in India were locally exposed in their district and year of birth and the wages that they earn as adults. A 1 percentage point reduction in infant mortality (or 10 point reduction in IMR) in an infant's district and year of birth is associated with an approximately 2 percent increase in his subsequent adult wages.
View Article and Find Full Text PDFJ Mark Access Health Policy
December 2015
Faculty of Medicine Public Health Department Research Unit EA 3279, University Aix-Marseille Marseille, France.
The slow reaction of French authorities to the so-called Mediator® saga in 2009 in France led to investigations that questioned the way conflicts of interest are reported. France implemented the ('Bertrand Law') in May 2013, known as the 'French Sunshine Act', with the aim of specifying the scope of disclosure obligations. This policy research reviewed the and reported case law from the French Council of State (COS) related to conflicts of interest in French Health technology assessment (HTA) opinion.
View Article and Find Full Text PDFJ Clin Epidemiol
April 2016
University Paris Diderot, Paris Sorbonne Cité, EA 7334 (REMES), Patient-Centered Outcomes Research, Paris, France; AP-HP, Hôtel-Dieu Hospital, URC ECO, 1 Place du Parvis Notre-Dame, 75004, Paris, France; Internal Medicine and Clinical Immunology, Bicêtre Hospital, AP-HP, 78, avenue du Général Leclerc 94270 Le Kremlin-Bicêtre, France.
Objectives: To identify a simplified factor structure for the PROQOL-human immunodeficiency virus (HIV) questionnaire to improve the measurement of the health-related quality of life (HRQL) of HIV-positive patients in clinical care and research settings.
Study Design And Setting: HRQL data were collected using the eight-dimension PROQOL-HIV questionnaire from 2,537 patients (VESPA2 study). Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) validated a simpler four-factor structure and assessed measurement invariance (MI).
Adv Tech Stand Neurosurg
February 2016
Department of Neurosurgery, Timone Hospital, Marseille, France.
The current first-line treatment of malignant gliomas consists in surgical resection (if possible) as large as possible. The existing tools don't permit to identify the limits of tumor infiltration, which goes beyond the zone of contrast enhancement on MRI. The fluorescence-guided malignant gliomas surgery was started 15 years ago and had become a standard of care in many countries.
View Article and Find Full Text PDFJ Acquir Immune Defic Syndr
July 2015
*Institut de Recherche pour le Développement, University Montpellier 1, UMI 233 TransVIHMI, Montpellier, France; †Central Hospital, Yaoundé, Cameroon; ‡INSERM, U912 (SESSTIM), Marseille, France; §University Aix Marseille, IRD, UMR-S912, Marseille, France; ‖ORS PACA, Observatoire Régional de la Santé Provence Alpes Côte d'Azur, Marseille, France; ¶AP-HP, Hôpital Bichat-Claude Bernard, Laboratoire de Pharmaco-Toxicologie, Paris, France; #IAME, UMR 1137, University Paris Diderot, Sorbonne Paris Cité and INSERM, Paris, France; and **Department of Infectious and Tropical Diseases, University Hospital, Montpellier, France.
Background: Evidence of gender differences in antiretroviral treatment (ART) outcomes in sub-Saharan Africa is conflicting. Our objective was to assess gender differences in (1) adherence to ART and (2) virologic failure, immune reconstitution, mortality, and disease progression adjusting for adherence.
Methods: Cohort study among 459 ART-naive patients followed up 24 months after initiation in 2006-2010 in 9 rural district hospitals.
J Mol Med (Berl)
August 2015
INSERM UMR_S910, GMGF, University Aix-Marseille, Marseille, France.
Cardiac fibroblasts are a major cell population of the heart and are characterized by their capacity to produce extracellular matrix (ECM). In hearts subjected to pressure overload, excessive fibroblast accumulation is responsible for fibrosis of the myocardium, a major clinical issue. Hence, understanding mechanisms generating fibroblasts in this context has become a key question in the cardiovascular field.
View Article and Find Full Text PDFElife
April 2015
Institut de génomique fonctionnelle de Lyon, Centre National de Recherche Scientifique, Lyon, France.
Hox proteins are well-established developmental regulators that coordinate cell fate and morphogenesis throughout embryogenesis. In contrast, our knowledge of their specific molecular modes of action is limited to the interaction with few cofactors. Here, we show that Hox proteins are able to interact with a wide range of transcription factors in the live Drosophila embryo.
View Article and Find Full Text PDFJ Mark Access Health Policy
April 2016
Faculty of Medicine, Public Health Department, Research Unit EA 3279, University Aix-Marseille, Marseille, France.
Background And Objectives: External reference pricing (ERP) is a price regulation tool widely used by policy makers in the European Union (EU) Member States (MS) to contain drug cost, although in theory, it may contribute to modulate prices up and down. The objective of this article was to summarise and discuss the main findings of part of a large project conducted for the European Commission ('External reference pricing of medicinal products: simulation-based considerations for cross-country coordination'; see www.ec.
View Article and Find Full Text PDFVaccine
January 2015
Mayo Vaccine Research Group, Mayo Clinic, Rochester, MN, USA.
Technol Health Care
November 2015
ENDEPUSresearch, Inc. www.endepusresearchinc.com University Aix Marseille, France.
The global burden of diseases is predicted to increase considerably in the coming decades (GBD project, WHO, 2010 [1]) - WHO-World Bank study, 1991 [2]); for example, the World Alzheimer Report and the UN Declaration on Non-Communicable Diseases estimate that the burden associated with dementia will increase 2-fold by 2030 and 3-4-fold by 2050. Therefore, urgent needs must be met in order to help policy-makers deal with the increasing societal costs of diseases. Recent technologies can facilitate the detection and prevention of mild cases of cognitive impairments, or integrative genomic medicine can target more individualized genetic traits and pedigrees; however, scientists do not necessarily agree: results from a recent population-based study using population imaging [3] differed from results obtained using integrative genomics approaches [4], and controversy exists between molecular biologists [5,6] and geneticists [7,8] with respect to asthma genetics.
View Article and Find Full Text PDFValue Health
November 2014
University Aix-Marseille, Marseille, France.
Value Health
November 2014
University Aix-Marseille, Marseille, France.