1,532 results match your criteria: "University "Parthenope"[Affiliation]"

There are a lot of evidences on the beneficial effects mediated by exercise on the prevention of not communicable diseases (NCDs) including different type of cancer. The production of circulating exerkines transported in exosomes represents a novel pathway activated by exercise. However, the biological mechanisms that could explain the role of exosomes in cancer prevention have been not fully elucidated.

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This paper investigates the link between organic and local food products purchasing as pro-environmental behaviours, and "other-regarding preferences", such as altruism, intrinsic motivation and self-image, which is measured through individuals' environmental concerns, volunteering, participation in ecological associations and pro-social behaviours. Using the Italian data from the Multipurpose survey on households "Aspects of daily life" conducted in 2019, and bivariate probit models, this paper shows that environmental egoistic and altruistic concerns, volunteering in formal organizations and participation in ecological associations are positively correlated with the purchase of more organic and local food products. Higher pro-social behaviours correlate positively with the purchase of more local products and negatively with the purchase of more organic products.

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Transcriptional Regulation and Its Misregulation in Human Diseases.

Int J Mol Sci

May 2023

Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.

Transcriptional regulation is a critical biological process that allows the cell or an organism to respond to a variety of intra- and extracellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity [...

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Agomelatine (AGM) is one of the latest atypical antidepressants, prescribed exclusively for the treatment of depression in adults. AGM belongs to the pharmaceutical class of melatonin agonist and selective serotonin antagonist ("MASS"), as it acts both as a selective agonist of melatonin receptors MT1 and MT2, and as a selective antagonist of 5-HT2C/5-HT2B receptors. AGM is involved in the resynchronization of interrupted circadian rhythms, with beneficial effects on sleep patterns, while antagonism on serotonin receptors increases the availability of norepinephrine and dopamine in the prefrontal cortex, with an antidepressant and nootropic effect.

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In this paper, a deep learning technique for tumor detection in a microwave tomography framework is proposed. Providing an easy and effective imaging technique for breast cancer detection is one of the main focuses for biomedical researchers. Recently, microwave tomography gained a great attention due to its ability to reconstruct the electric properties maps of the inner breast tissues, exploiting nonionizing radiations.

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Thermal ablation is a minimally invasive technology used to treat many types of tumors, including lung cancer. Specifically, lung ablation has been increasingly performed for unsurgical fit patients with both early-stage primi-tive lung cancer and pulmonary metastases. Image-guided available techniques include radiofrequency ablation, microwave ablation, cryoablation, laser ablation and irreversible electroporation.

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The Effectiveness of Pan-Sharpening Algorithms on Different Land Cover Types in GeoEye-1 Satellite Images.

J Imaging

April 2023

DIST-Department of Science and Technology, Parthenope University of Naples, Centro Direzionale, Isola C4, 80143 Naples, Italy.

In recent years, the demand for very high geometric resolution satellite images has increased significantly. The pan-sharpening techniques, which are part of the data fusion techniques, enable the increase in the geometric resolution of multispectral images using panchromatic imagery of the same scene. However, it is not trivial to choose a suitable pan-sharpening algorithm: there are several, but none of these is universally recognized as the best for any type of sensor, in addition to the fact that they can provide different results with regard to the investigated scene.

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The propensity of manufacturers to produce goods at affordable cost, with more accuracy, and at a faster rate force them to search for novel solutions, such as deploying robots in place of people in a sector that can accommodate their needs. Welding is one of the most crucial processes in the automotive industry. This process is time-consuming, subject to error, and demands skilled professionals.

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Background: B-raf inhibitors (BRAFi) are effective for BRAF-mutated papillary (PTC) and anaplastic (ATC) thyroid carcinomas, although acquired resistance impairs tumour cells' sensitivity and/or limits drug efficacy. Targeting metabolic vulnerabilities is emerging as powerful approach in cancer.

Methods: In silico analyses identified metabolic gene signatures and Hif-1α as glycolysis regulator in PTC.

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Metabolic syndrome (MetS) is defined by a cluster of several cardio-metabolic risk factors, specifically visceral obesity, hypertension, dyslipidemia, and impaired glucose metabolism, which together increase risks of developing future cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D). This article is a narrative review of the literature and a summary of the main observations, conclusions, and perspectives raised in the literature and the study projects of the Working Group of Childhood Obesity (WGChO) of the Italian Society of Paediatric Endocrinology and Diabetology (ISPED) on MetS in childhood obesity. Although there is an agreement on the distinctive features of MetS, no international diagnostic criteria in a pediatric population exist.

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Purpose: To investigate the effects of the "11 for Health" programme on musculoskeletal fitness.

Methods: A total of 108 Danish children aged 10-12 years participated in the study, with 61 children in the intervention group (IG, 25 girls and 36 boys) and 47 children in the control group (CG, 21 girls and 26 boys). Measurements were conducted before and after an 11-week intervention consisting of twice-weekly 45-min football training sessions for IG or continuation of normal Physical Education program for CG.

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Application of "Galileo High Accuracy Service" on Single-Point Positioning.

Sensors (Basel)

April 2023

International PhD Programme UNESCO Chair "Environment, Resources and Sustainable Development", Department of Science and Technology, "Parthenope" University of Naples, 80143 Napoli, Italy.

Employment of precise positioning techniques will enable low-cost receivers for a variety of applications. The complexity of techniques such as Precise Point Positioning (PPP), or differential techniques that require the use of external sources of corrections, could be a disadvantage for users. On the other hand, a simple technique such as Single-Point Positioning (SPP) alone does not provide high-level accuracy.

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Opioids are substances derived from opium (natural opioids). In its raw state, opium is a gummy latex extracted from . The use of opioids and their negative health consequences among people who use drugs have been studied.

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In recent decades, meat consumption has increased globally due to increased incomes. A consequence of increased red meat consumption has been the rise in greenhouse gas emissions and nutrition-related diseases. Consumption of antibiotic-free (ABF) poultry meat is a viable healthy and sustainable substitute that will cause less damage to humans and the environment in the long run.

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Cannabis and Paternal Epigenetic Inheritance.

Int J Environ Res Public Health

April 2023

Dipartimento di Scienze Motorie e del Benessere, Università di Napoli Parthenope, 80133 Napoli, Italy.

Cannabis is the most widely used illicit drug in Western counties and its abuse is particularly high in male adolescents and young adults. Its main psychotropic component, the cannabinoid delta-9-tetrahydrocannabinol (Δ-THC), interferes in the endogenous endocannabinoid system. This signaling system is involved in the control of many biological activities, including the formation of high-quality male gametes.

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Axilla is a pyramidal-in-shape "virtual cavity" housing multiple anatomical structures and connecting the upper limb with the trunk. To the best of our knowledge, in the pertinent literature, a detailed sonographic protocol to comprehensively assess the axillary region in daily practice is lacking. In this sense, the authors have briefly described the anatomical architecture of the axilla-also using cadaveric specimens-to propose a layer-by-layer sonographic approach to this challenging district.

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Introduction: It is widely demonstrated that high frequency (HF) repetitive transcranial magnetic stimulation (rTMS) has facilitative effects and is therefore capable to inducing changes in motor responses. One of the most investigated areas is the dorsolateral prefrontal cortex (DLPFC) as it plays a special executive attention role in actively preserving access to stimulus representations and objectives in environments with plenty of distraction such as those of team sports. Volleyball is a team sport in which the attention and coordination components are essential for achieving performance.

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Karakoram Highway (KKH) is frequently disrupted by geological hazards mainly landslides which pose a serious threat to its normal operation. Using documented inventory, optical imagery interpretation, and frequency-area statistics, the features of slope failure, the spatial distribution, and their link to numerous contributing factors have all been effectively explored along the KKH. An updated inventory for the area was recreated using the interferometric synthetic aperture radar (InSAR) persistent scatterer (PS) technology to further investigate millimetre-accurate measurements of slope deformation (V).

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Do new cement-based mortars pose a significant threat to the aquatic environment?

Chemosphere

August 2023

ENEA CR PORTICI, P. le E. Fermi 1, 80055, Portici, NA, Italy. Electronic address:

Nowadays, the use of multi-functional mortars has increased significantly, with interesting applications in the sustainable construction. In the environment, the cement-based materials are subjected to leaching, so the assessment of potential adverse effects upon aquatic ecosystem is necessary. This study focuses on the evaluation of the ecotoxicological threat and of a new type of cement-based mortar (CPM-D) and its raw materials leachates.

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Objectives: Severe acute respiratory syndrome - coronavirus 2 (SARS-CoV-2) is a single-stranded positive ribonucleic acid virus of the coronaviridae family. The disease caused by this virus has been named by the World Health Organization coronavirus disease 19 (COVID-19), whose main manifestation is interstitial pneumonia. Aim of this study is to describe the radiological features of SARS-CoV-2 infection in its original form, to correlate the high-resolution computed tomography (HRCT) patterns with clinical findings, prognosis and mortality, and to establish the need for treatment and admission to the intensive care unit.

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GIPR expression is induced by thiazolidinediones in a PPARγ-independent manner and repressed by obesogenic stimuli.

Eur J Cell Biol

June 2023

Institute of Genetics and Biophysics ''Adriano Buzzati-Traverso'', CNR, Via P. Castellino 111, 80131 Naples, Italy; NBFC, National Biodiversity Future Center, Palermo 90133, Italy. Electronic address:

Adipose tissue (AT) dysfunctions are associated with the onset of insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Targeting glucose-dependent insulinotropic peptide receptor (GIPR) is a valid option to increase the efficacy of glucagon-like peptide 1 (GLP-1) receptor agonists in T2DM treatment. Nevertheless, the therapeutic potential of targeting the GIP/GIPR axis and its effect on the AT are controversial.

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Cutaneous melanoma (CM) remains one of the leading causes of tumor mortality due to its high metastatic spread. CM growth is influenced by inflammation regulated by prostaglandins (PGs) whose synthesis is catalyzed by cyclooxygenases (COXs). COX inhibitors, including non-steroidal anti-inflammatory drugs (NSAIDs), can inhibit tumor development and growth.

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Xanthine oxidase (XO) is a flavoprotein catalysing the oxidation of hypoxanthine to xanthine and then to uric acid, while simultaneously producing reactive oxygen species. Altered functions of XO may lead to severe pathological diseases, including gout-causing hyperuricemia and oxidative damage of tissues. These findings prompted research studies aimed at targeting the activity of this crucial enzyme.

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A further methodologic comment on Recalcati et al's response on the "skull with petrified ears" on the necessity of evidence-based anthropologic studies.

Clin Dermatol

November 2023

Forensic Anthropology, Paleopathology, and Bioarchaeology (FAPAB) Research Center, Avola, Italy; Department of Motor Sciences and Wellness, School of Sciences, Engineering, and Health, University of Naples "Parthenope", Naples, Italy. Electronic address:

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Extended-release metformin improves cognitive impairment in frail older women with hypertension and diabetes: preliminary results from the LEOPARDESS Study.

Cardiovasc Diabetol

April 2023

Department of Medicine, Division of Cardiology, Einstein Institute for Aging Research, Fleischer Institute for Diabetes Research (FIDAM), Einstein - Mount Sinai Diabetes Research Center (ES-DRC), Albert Einstein College of Medicine, New York City, NY, USA.

Article Synopsis
  • Women are at a high risk of frailty, and factors like diabetes and hypertension increase this risk, with metformin potentially helping to reduce frailty symptoms in post-menopausal women.
  • A study was conducted involving frail older women and men with diabetes and hypertension to evaluate the cognitive effects of an extended-release formulation of metformin over 6 months.
  • Results showed significant improvements in cognitive performance for women taking extended-release metformin compared to those not treated, as well as differences between treatment responses in men and women, indicating the drug's positive impact on cognitive health in this demographic.
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