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GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinoma.
Gut
March 2023
Departament de Medicina i Ciències de la Vida, Universitt Pompeu Fabra, Barcelona, Spain
Objective: GATA6 is a key regulator of the classical phenotype in pancreatic ductal adenocarcinoma (PDAC). Low GATA6 expression associates with poor patient outcome. is the second most expressed GATA factor in the pancreas.
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