Tracking mosquito-borne diseases via social media: a machine learning approach to topic modelling and sentiment analysis.

Mosquito-borne diseases (MBDs) are a major threat worldwide, and public consultation on these diseases is critical to disease control decision-making. However, traditional public surveys are time-consuming and labor-intensive and do not allow for timely decision-making. Recent studies have explored text analytic approaches to elicit public comments from social media for public health.

Effects of Gamma Irradiation on Structural, Chemical, Bioactivity and Biocompatibility Characteristics of Bioactive Glass-Polymer Composite Film.

Gamma irradiation is an effective technique for biocomposite films intended for application in tissue engineering (TE) to ensure sterility and patient safety prior to clinical applications. This study proposed a biocomposite film composed of natural polymer chitosan (CS) and synthetic polymer poly-Ɛ-caprolactone (PCL) reinforced with sol-gel-derived bioactive glass (BG) for potential application in TE. The BG/PCL/CS biocomposite film was sterilized using 25 kGy gamma rays, and subsequent changes in its characteristics were analyzed through mechanical and physical assessment, bioactivity evaluation via immersion in simulated body fluid (SBF) and biocompatibility examination using human primary dermal fibroblasts (HPDFs).

Paediatricians' knowledge, perceptions, preparedness and involvement towards paediatric antimicrobial stewardship in Pakistan: findings and the implications.

Introduction: Antibiotics are frequently prescribed for neonates and children. However, this can be excessive with inappropriate prescribing leading to increased antimicrobial resistance (AMR). Paediatricians are key initiators of antibiotics.

UHPLC-MS/MS standardized extract of leaf inhibits CYP2C9 and CYP3A4 activities in hepatic cells of control and streptozotocin-induced diabetic rats.

Objectives: Del. is a perennial tropical shrub from Asteraceae. The fresh leaf of is consumed as a vegetable due to its medicinal and nutritional properties.

Parental experience with childhood COVID-19 vaccines and factors associated with parental hesitancy despite being vaccinated: findings of a cross-sectional analysis from Pakistan and implications for the future.

Objectives: This study examined parental experiences with COVID-19 vaccination and factors contributing to COVID-19 vaccine hesitancy (CVH) among them to help guide future policy initiatives.

Design: Cross-sectional study.

Setting: Lahore, the second largest metropolis in Pakistan.

Prenatal diagnosis of achondroplasia in primary care settings - Recognising the soft markers: A case report.

Achondroplasia, a genetic disorder causing limb shortening, is the most common form of disproportionate dwarfism. It can be diagnosed prenatally through sonographic findings and postnatally through clinical and radiological findings. Currently, an increasing number of affected foetuses are diagnosed antenatally since prenatal ultrasonography is routinely conducted in primary care settings.

Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum.

Malaysian seaweed, particularly Sargassum polycystum, has potential for alginate production, yet an extraction protocol for this seaweed remains lacking. This study aimed to optimize the extraction process to maximize alginate yield while characterizing the physicochemical properties of the extracted alginate and its potential applications. An alkali-based extraction method was employed, with key parameters, including alkali concentration, extraction temperature, and time, carefully optimized to yield 30.

Analysis of twelve human milk oligosaccharides over fifteen months post-partum in human milk from Chinese mothers.

Human milk Oligosaccharides (HMOs) are a major component in human milk and recognized to play an important role in modulating gut microbiota, intestinal cell response, and the development of the brain and immune system. While HMOs levels from Chinese mothers across different regions of China have been reported, data from Hebei are lacking. Twelve HMOs were measured from a cross-section of Hebei Han mothers over a 15-month lactation period.

Long-Term clinical efficacy of liraglutide for type 2 diabetes: real-world evidence and outcomes from Pakistan.

Background: Liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has demonstrated efficacy in improving glycemic control and promoting weight loss in clinical trials. However, real-world data from diverse populations, particularly from South Asia, are limited. The study aims to evaluate the long-term efficacy and safety of liraglutide in a real-world setting among Pakistani patients with type 2 diabetes mellitus (T2DM).

Examining the evolution and impact of OTC vending machines in Global Healthcare Systems.

Background: The study of over the counter (OTC) vending machines is crucial given their growing popularity and potential impact on the pharmaceutical industry and consumer behaviour.

Objectives: This study involves a bibliometric quantitative analysis of academic literature to evaluate OTC vending machines in terms of their evolution, current trends, and potential areas for future research

Methods And Materials: The Scopus database was searched using its advanced search tool, focusing on papers that included the search query in their titles, abstracts, and keywords. Data analysis included bibliometric indicators such as publication counts, citation trends, and co-authorship networks, which were visualized using VOSviewer software (version 1.

Case Series of Streptococcus pneumoniae Keratitis and Its Sequelae.

is a more prevalent cause of corneal ulcers in developing countries than in developed countries. We report five cases of corneal ulcers attributed to this organism with a literature review on bacterial cornea ulcers. Among the patients, four had underlying systemic illnesses while one was otherwise healthy.

Assessment of hypolipidemic potential of cholesteryl esterase inhibitory peptides in different probiotic fermented milk through in vitro, , and molecular docking studies.

Fermented milk (FM) is well-known to confer health-promoting benefits, particularly for managing chronic metabolic diseases. However, the specific cholesterol esterase (CE) inhibitory activities of FM produced from different animal milk sources have not been extensively explored. This study for the first time investigates the CE inhibition potential of FM derived from bovine (F_BM), camel (F_CM), sheep (F_SM), and goat milk (F_GM), each fermented with five different probiotic strains and stored for 14 days under refrigeration.

A review of convolutional neural network based methods for medical image classification.

This study systematically reviews CNN-based medical image classification methods. We surveyed 149 of the latest and most important papers published to date and conducted an in-depth analysis of the methods used therein. Based on the selected literature, we organized this review systematically.

Factors influencing sleep quality among nurses in tertiary hospitals in Kelantan, Malaysia: a cross-sectional study.

Background: Poor sleep quality among nurses can negatively impact their performance, leading to increased risks of errors in nursing practice, which directly affect patient safety. However, there is limited research on the factors influencing sleep quality and its subsequent consequences on patient safety, particularly in tertiary hospitals in Kelantan, Malaysia. This study aimed to determine the factors influencing sleep quality and the prevalence of poor sleep quality among nurses at tertiary hospitals in Kelantan.