1 results match your criteria: "Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia ctefliza@upm.edu.my.[Affiliation]"
kinetic release study, antimicrobial activity and toxicity profile of a kojic acid ester-based nanoemulsion for topical application.
RSC Adv
November 2020
Integrated Chemical BioPhysics Research Centre, Faculty of Science, Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia
Article Synopsis
- Nanoemulsions, particularly the kojic acid ester-based nanoemulsion (KAE-NA), show promise for drug delivery with increased permeation rates, reaching over 59% at 8 hours.
- The KAE-NA demonstrated effective antimicrobial activity against ATCC 43300, outperforming its active component, kojic acid ester, in inhibition zone size.
- Toxicity tests on embryonic zebrafish indicated KAE-NA is relatively safe, with high survival rates and no deformities observed at doses up to 250 μg/mL.