Development and validation of the Newborn Clubfoot Screening Checklist to improve the detection of postnatal congenital talipes equinovarus among newborns by non-orthopaedic-trained healthcare workers in Sarawak General Hospital: A cross-sectional prospective study.

Introduction: Non-orthopaedic-trained healthcare professionals face challenges in identifying postnatal clubfoot deformities due to the lack of suitable assessment tools, resulting in misdiagnosis. Therefore, this study aimed to develop and validate the Neonatal Clubfoot Screening Checklist (NCSC) to assist non-orthopaedic-trained healthcare professionals in postnatal clubfoot assessment.

Methods: The NCSC development involved five phases: conceptual understanding of deformity components, creation of pictorial representations, tool structure design, content and face validation, pilot study and field study.

Roles of probiotics against HPV through the gut-vaginal axis.

Human papillomavirus (HPV) is a sexually transmitted virus, whose persistent infection is the main reason for invasive cervical cancer (ICC), which is the fourth most common type of cancer in women, with more than 500 000 new cases every year. After infection, various alterations occur in the host, facilitating the virus's evasion of immune system clearance and promoting its proliferation. Oral probiotic consumption can influence the whole body's immunity, inflammatory reflection, neural, endocrine humoral, metabolic pathways and other organs by adjusting the components of gut microbiota (GM).

Evidence for motivational interviewing in educational settings among medical schools: a scoping review.

Background: Motivational interviewing (MI) is a person-centred approach focused on empowering and motivating individuals for behavioural change. Medical students can utilize MI in patient education to engage with patients' chronic health ailments and maladaptive behaviours. A current scoping review was conducted to 1) determine the types of MI (conventional, adapted, brief and group MI) education programs in medical schools, delivery modalities and teaching methods used; 2) classify educational outcomes on the basis of Kirkpatrick's hierarchy; and 3) determine the key elements of MI education via the FRAMES (feedback, responsibility, advice, menu of options, empathy, self-efficacy) model.

Gaps in cancer care in a multi-ethnic population in Sarawak, Borneo: A central referral centre study.

Background: The state of Sarawak on the island of Borneo in East Malaysia, in working towards developing and strengthening cancer services through a holistic patient-centred approach, must focus on the comprehensive needs of cancer patients by taking into account the psycho-social, cultural and spiritual aspects of Sarawak's multi-ethnic, multi-cultural population.

Methods: A 42-item survey questionnaire was developed and validated with a total of 443 patients. The perceived importance of information provided and level of patient satisfaction were assessed with a 5-point Likert scale in 10 domains (Diagnosis, Surgery, Radiotherapy, Systemic therapy, Clinical trials, Pain management, Treatment monitoring, Psychosocial support, Sexual care and fertility issues, and Financial support).

Molecular simulation of [P8883][TfN] ionic liquid decorated silica in 6FDA-ODA based mixed matrix membrane for enhanced CO/CH separation.

Mixed-matrix membranes (MMMs) have been reported to have considerable scope in gas separation applications because of their merged inherent strength of a durable polymer matrix and the exceptional performance capabilities of inorganic fillers. The selection of comparatively suitable polymers with fillers that can match each other and boost interfacial compatibility while ensuring uniform dispersion of filler within the polymer is still intensively demanding and is challenging at the experimental scale. Ionic liquids (ILs) are effective in promoting better dispersion and compatibility, leading to improved separation performance.

A review on recent advances of cellulose acetate membranes for gas separation.

This review thoroughly investigates the wide-ranging applications of cellulose-based materials, with a particular focus on their utility in gas separation processes. By focusing on cellulose acetate (CA), the review underscores its cost-effectiveness, robust mechanical attributes, and noteworthy CO solubility, positioning it as a frontrunner among polymeric gas separation membranes. The synthesis techniques for CA membranes are meticulously examined, and the discourse extends to polymeric blend membranes, underscoring their distinct advantages in gas separation applications.

Higher prevalence of harbouring BCR::ABL1 in first-degree relatives of chronic myeloid leukaemia (CML) patients compared to normal population.

Background: The role of familial influence in chronic myeloid leukaemia (CML) occurrence is less defined. Previously, we conducted a study to determine the prevalence of harbouring BCR::ABL1 in our local adult normal population (designated as Study). We present our current study, which investigated the prevalence of harbouring BCR::ABL1 in the normal first-degree relatives of local CML patients (designated as Study).

Clinical translation for targeting DNA damage repair in non-small cell lung cancer: a review.

Despite significant advancements in screening, diagnosis, and treatment of non-small cell lung cancer (NSCLC), it remains the primary cause of cancer-related deaths globally. DNA damage is caused by the exposure to exogenous and endogenous factors and the correct functioning of DNA damage repair (DDR) is essential to maintain of normal cell circulation. The presence of genomic instability, which results from defective DDR, is a critical characteristic of cancer.

Screening of Metal Oxides and Hydroxides for Arsenic Removal from Water Using Molecular Dynamics Simulations.

Arsenic in groundwater is a harmful and hazardous substance that must be removed to protect human health and safety. Adsorption, particularly using metal oxides, is a cost-effective way to treat contaminated water. These metal oxides must be selected systematically to identify the best material and optimal operating conditions for the removal of arsenic from water.

The influence of meaningful work on the mental health of SME employees in the COVID-19 era: can coping strategies mediate the relationship?

Background: Stress, depression, and anxiety are prevalent issues among SME employees during the COVID-19 pandemic. Even while having meaningful work that expressively contributes to individual growth has been related to improving mental health, employees' work may also need to adopt coping strategies to increase outcomes. The purpose of this study was to examine the relationship between meaningful work (positive meaning, meaning-making, and greater good motivations) and mental health, as well as coping strategies (problem-focused and emotion-focused) as a mediator of this relationship.

Synthesis of molecularly imprinted polymer by precipitation polymerization for the removal of ametryn.

Ametryn (AME) is a triazine herbicide which is mainly used to kill unwanted herbs in crops. Despite its importance in agriculture, the usage of AME also poses a risk to humans and the ecosystem due to its toxicity. Hence, it is important to develop a method for the effective removal of AME from various water sources which is in the form of molecular imprinting polymer (MIP).

Spatial analyses of Plasmodium knowlesi vectors with reference to control interventions in Malaysia.

Background: Malaria parasites such as Plasmodium knowlesi, P. inui, and P. cynomolgi are spread from macaques to humans through the Leucosphyrus Group of Anopheles mosquitoes.

Analysing the current status, hotspots, and future trends of technology management: Using the WoS and scopus database.

This study presents a comprehensive overview of the development process and the latest trends in technology management (TM), laying a robust foundation for further advancements in this domain. To achieve this, we analysed 1944 TM articles from the Web of Science database and 2642 articles from Scopus, spanning the last 20 years. Employing methodologies that involve scientific knowledge graphs and bibliometrics, we analysed diverse aspects such as changes in the annual publication of articles; geographical distribution among countries, institutions, disciplines, and authors; keyword co-occurrence and clusters; and timezone view.

Obstructive sleep apnea and vitamin D: an updated systematic review and meta-analysis.

Unlabelled: PURPOSE  : Obstructive sleep apnea (OSA) is a chronic, sleep-related breathing disorder which leads to increased cardiovascular risks. Vitamin D deficiency is associated with various cardiometabolic complications, including increased cardiovascular morbidity and mortality. We aimed to analyze the difference in serum 25-hydroxyvitamin D (25-OHD) level, prevalence of vitamin D insufficiency and deficiency, and the effect of CPAP treatment on serum 25-OHD levels among adult patients with OSA.

From ToyBox Study to eToyBox: Advancing Childhood Obesity Reduction in Malaysian Kindergartens.

Prevention and treatment of childhood obesity is a global concern, and in Malaysia, it is considered a national public health priority. Determinants of childhood obesity are multifactorial and include factors that directly and indirectly influence energy balance-related behaviours, including energy intake and energy expenditure. Interventions to address childhood obesity that have multiple components at different levels have been shown to be the most influential.

Phylogeography of the Sunda pangolin, : Implications for taxonomy, conservation management and wildlife forensics.

The Sunda pangolin () is the most widely distributed Asian pangolin species, occurring across much of Southeast Asia and in southern China. It is classified as Critically Endangered and is one of the most trafficked mammals in the world, which not only negatively impacts wild Sunda pangolin populations but also poses a potential disease risk to other species, including humans and livestock. Here, we aimed to investigate the species' phylogeography across its distribution to improve our understanding of the species' evolutionary history, elucidate any taxonomic uncertainties and enhance the species' conservation genetic management and potential wildlife forensics applications.

Recent progress in the production and application of biochar and its composite in environmental biodegradation.

Over the past few decades, extensive research has been conducted to develop cost-effective and high-quality biochar for environmental biodegradation purposes. Pyrolysis has emerged as a promising method for recovering biochar from biomass and waste materials. This study provides an overview of the current state-of-the-art biochar production technology, including the advancements and biochar applications in organic pollutants remediation, particularly wastewater treatment.

Distraction descriptor for brainprint authentication modelling using probability-based Incremental Fuzzy-Rough Nearest Neighbour.

This paper aims to design distraction descriptor, elicited through the object variation, to refine the granular knowledge incrementally, using the proposed probability-based incremental update strategy in Incremental Fuzzy-Rough Nearest Neighbour (IncFRNN) technique. Most of the brainprint authentication models were tested in well-controlled environments to minimize the influence of ambient disturbance on the EEG signals. These settings significantly contradict the real-world situations.

Cryptic Diversity and Demographic Expansion of Malaria Vectors in Malaysia.

Although Malaysia is considered free of human malaria, there has been a growing number of cases. This alarming trend highlighted the need for our understanding of this parasite and its associated vectors, especially considering the role of genetic diversity in the adaptation and evolution among vectors in endemic areas, which is currently a significant knowledge gap in their fundamental biology. Thus, this study aimed to investigate the genetic diversity of , , , and -the vectors for malaria in Malaysia.

The evolutionary history of hepaciviruses.

In the search for natural reservoirs of hepatitis C virus (HCV), a broad diversity of non-human viruses within the genus has been uncovered. However, the evolutionary dynamics that shaped the diversity and timescale of hepaciviruses evolution remain elusive. To gain further insights into the origins and evolution of this genus, we screened a large dataset of wild mammal samples ( 1,672) from Africa and Asia, and generated 34 full-length hepacivirus genomes.

In Vitro Antioxidant and Fibroblast Migration Activities of Fractions Eluded from Dichloromethane Leaf Extract of .

(1) The complexity of diabetes and diabetic wound healing remains a therapeutic challenge because proper and systematic wound care and management are essential to prevent chronic microbial infection and mechanical damage to the skin. , locally known as 'Kacip Fatimah', is an herb that has been previously reported to possess anti-inflammatory, analgesic, antinociceptive and antipyretic properties. The current study aims to assess the antioxidant and fibroblast cell migration activities of the fractions eluded from the dichloromethane extract of leaves.

A review on co-pyrolysis of agriculture biomass and disposable medical face mask waste for green fuel production: recent advances and thermo-kinetic models.

The Association of Southeast Asian Nations is blessed with agricultural resources, and with the growing population, it will continue to prosper, which follows the abundance of agricultural biomass. Lignocellulosic biomass attracted researchers' interest in extracting bio-oil from these wastes. However, the resulting bio-oil has low heating values and undesirable physical properties.

Preferred cataract surgery practices in Malaysia: a survey based study.

Background: To describe the preferred cataract surgery practices among Malaysian ophthalmologists and medical officers in comparison with the recommended practices.

Methods: An online questionnaire was sent out in April 2021, to Malaysian Ophthalmologists and medical officers who perform cataract surgeries. The questions were focused on the preferred cataract surgery practices of the participants.