Chalcone Mannich base derivatives: synthesis, antimalarial activities against , and molecular docking analysis.

Development and discovery of new antimalarial drugs are needed to overcome the multi-resistance of parasites to commercially available drugs. Modifying the substitutions on the amine groups has been shown to increase antimalarial activities and decrease cross-resistance with chloroquine. In this study, we have synthesized several chalcone derivatives the substitution of aminoalkyl groups into the aromatic chalcone ring using the Mannich-type reaction.

Synthesis of mesoporous zeolite Y using extract as natural organic surfactant for deoxygenation of oil to biofuel.

Saponin is a plant-derived chemical with an amphiphilic glycoconjugate structure extracted from sapindaceae plants like . This study investigated saponin extract of as a natural template for formation of mesoporous zeolite Y. Surface area and mesoporosity of zeolite Y were improved with optimization of extract (SRE) concentration (Y-Ln; = 2, 5, 10 or 15 mL), reaching 216.

Direct synthesis of Fe-aluminosilicates from red mud for catalytic deoxygenation of waste cooking oil.

Conversion of red mud (RM) that contains a high level of silica, alumina and iron minerals into heterogenous catalysts, offers a route for the utilization of abundant toxic by-products of bauxite refining. In this study, the conversion of red mud into mesoporous Fe-aluminosilicate produced selective catalysts for the deoxygenation of waste cooking oil to green diesel hydrocarbons. Direct conversion of red mud in the presence cetyltrimethylammonium bromide into Fe-aluminosilicate (RM-CTA) produced a highly mesoporous structure with oligomeric FeO clusters within the pores.

Growth-control of hexagonal CdS-decorated ZnO nanorod arrays with low-temperature preheating treatment for improved properties and efficient photoelectrochemical applications.

The limitations of oxide semiconductor-based solar cells in achieving high energy conversion efficiencies have prompted incessant research efforts towards the creation of efficient heterostructures. Despite its toxicity, no other semiconducting material can fully replace CdS as a versatile visible light-absorbing sensitizer. Herein, we explore the of preheating treatment in the successive ionic layer adsorption and reaction (SILAR) deposition technique and improve the understanding of the principle and the effects of a controlled growth environment on thus-formed CdS thin films.

A New Complex Design of Fe (II) Isoleucine Dithiocarbamate as a Novel Anticancer and Antivirus against SARSCOV-2 (COVID-19).

Background: This study was carried out to synthesize a new complex of Fe(II) with isoleucine dithiocarbamate ligand and to determine its potential as an anticancer and antiviral agent for SARSCOV-2.

Methods: The synthesized complexes were then characterized by UV-vis and FT-IR spectroscopy and their melting points. The value of the conductivity of the complex compound is also determined.

Lewis acid Ni/Al-MCM-41 catalysts for H-free deoxygenation of oil to biofuels.

The activity of mesoporous Al-MCM-41 for deoxygenation of oil (RTO) was enhanced modification with NiO nanoparticles. Deoxygenation at atmospheric pressure and under H free conditions required acid catalysts to ensure the removal of the oxygenated fragments in triglycerides to form liquid hydrocarbons. NiO at different weight loadings was impregnated onto Al-MCM-41 and the changes of Lewis/Brønsted acidity and mesoporosity of the catalysts were investigated.

Two-level factorial analysis of the effect of fructose on DHA biosynthetic capacity of sp. SW1.

Thraustochytrids are getting increasingly popular due to their high potential role as alternative producers of the high-valued ω-3 polyunsaturated fatty acids (PUFA), docosahexaenoic acid (DHA). While most thraustochytrids prefer glucose as the major carbon source, few strains have been reported to prefer fructose. One such strain is sp.

Hydrogen-free hydrogenation of nitrobenzene direct coupling with cyclohexanol dehydrogenation over ordered mesoporous MgO/SBA-15 supported Cu nanoparticles.

Direct catalytic coupling of nitrobenzene hydrogenation and cyclohexanol dehydrogenation was studied in the gas phase over mesoporous MgO-SBA15 supported Cu nanoparticles. This approach avoids an external supply of H and utilizes the liberated H from the dehydrogenation step of the first reactant for the hydrogenation reaction of the second reactant. A catalyst series consisting of four Cu/MgO-SBA15 mesoporous solids with varying Cu loadings (5-20 wt%) were prepared and systematically characterized by BET, ICP, XRD, TPR, TPD, FT-IR, SEM, XPS, and TEM.

Development of bimetallic nickel-based catalysts supported on activated carbon for green fuel production.

In this work, the catalytic deoxygenation of waste cooking oil (WCO) over acid-base bifunctional catalysts (NiLa, NiCe, NiFe, NiMn, NiZn, and NiW) supported on activated carbon (AC) was investigated. A high hydrocarbon yield above 60% with lower oxygenated species was found in the liquid product, with the product being selective toward -(C + C)-diesel fractions. The predominance of -(C + C) hydrocarbons with the concurrent production of CO and CO, indicated that the deoxygenation pathway proceeded decarbonylation and decarboxylation mechanisms.

Sulfonated SnO nanocatalysts a self-propagating combustion method for esterification of palm fatty acid distillate.

Biodiesel derived from palm fatty acid distillate (PFAD) was produced catalytic esterification using sulfonated tin oxide (HSO /SnO) as the superacid solid catalyst. In this work, the SnO catalyst was synthesised by the self-propagating combustion (SPC) method, and activated using chlorosulfonic acid. The SPC method was able to produce nano-sized particles with homogenous size and shape that were anchored with many HSO ions, resulting in more exceptional acid properties that effectively esterified the PFAD feedstock into FAMEs (fatty acid methyl esters).

Data for the subsurface characterization of Pahang River Basin with the application of Transient Electromagnetic geophysical surveys.

The Transient Electro-Magnetic (TEM) geophysical technique was deployed to map and characterized the subsurface of Pahang River Basin along the East Coast Peninsula Malaysia. The data aimed at differentiating between the massive zones and the weak zones within the region, to also assess and differentiate the subsurface structures and comes up with recommendations for policy decision, formulation and plans on the flooding impact, surface water and groundwater managements, in addition to other environmental related issues ravaging the area. The data presented in this paper, showed the properties of the subsurface rocks underlain the region as beneficial to the Agriculturists; Climatologists; Engineers; Environmentalists; Geoscientists, Hydrologists and Policy formulation officers.

Influence of Mg/CTAB ratio on the structural, physicochemical properties and catalytic activity of amorphous mesoporous magnesium silicate catalysts.

This study investigated the physicochemical and catalytic properties of mesoporous magnesium silicate catalysts prepared at various Mg/CTAB ratios (0.25, 0.50, 0.

A study on the removal of propyl, butyl, and benzyl parabens newly synthesised ionic liquid loaded magnetically confined polymeric mesoporous adsorbent.

This study investigated the effectiveness of ionic liquids (ILs) loaded onto the surface of a polymeric adsorbent (βCD-TDI) grafted with modified magnetic nanoparticles (MNPs) an analysis of water treatment, which resulted in high removal of selected endocrine-disrupting chemicals (parabens). The syntheses of MNPs, MNP-βCD-TDI, and IL-MNP-βCD-TDI were characterised and compared using Fourier transform infrared (FT-IR) spectroscopy, carbon-hydrogen-nitrogen (CHN) analysis, vibrating sample magnetometry (VSM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), the Brunauer-Emmett-Teller (BET) method, thermogravimetric analysis (TGA), and X-ray diffraction (XRD). The results of SEM and TEM indicated that the pore size distribution exhibited mesoporous characteristics with a small surface area (BET analysis: 42.

GSK3β inhibition confers survival advantage in Burkholderia pseudomallei-infected hyperglycaemic mice by regulating inflammatory response.

Burkholderia pseudomallei, the etiologic agent of melioidosis is a common cause of sepsis mainly in diabetic individuals in South East Asia. Glycogen synthase kinase-3β (GSK3β) plays a pivotal role in modulating inflammatory balance in Gram-negative bacterial infections. In this study, we demonstrate that inhibition of GSK3β significantly improved survival of hyperglycaemic mice acutely infected with B.

Persistence of cyfluthrin in three Malaysian agricultural soils under laboratory conditions.

The influence of temperature, moisture and organic matter on the persistence of cyfluthrin was determined using three types of Malaysian soils, namely clay, clay loam and sandy clay loam obtained from a tomato farm in Cameron Highlands, Pahang. The persistence of cyfluthrin was observed in the laboratory at two temperature levels of 25 and 35 degreeC and field water capacity of 30 and 80%. Treated soil samples were incubated in a growth chamber for 1, 2, 3, 5, 7, 10, 14, 21 and 28 days.

Simulation of a Petri net-based model of the terpenoid biosynthesis pathway.

Background: The development and simulation of dynamic models of terpenoid biosynthesis has yielded a systems perspective that provides new insights into how the structure of this biochemical pathway affects compound synthesis. These insights may eventually help identify reactions that could be experimentally manipulated to amplify terpenoid production. In this study, a dynamic model of the terpenoid biosynthesis pathway was constructed based on the Hybrid Functional Petri Net (HFPN) technique.

Absorbed Dose to Water Determination Using IAEA, HPA, NACP, AAPM, NCRP and ICRU Protocols for 1.25 MeV Gamma Ray 6 MV and 10 MV X-Rays: An Intercomparison of Results when IAEA was taken as a Standard Protocol.

Absorbed dose to water was measured with ionisation chambers NE 2561 (#267), NE 2581 (#334), NE 2571 (#1028), using the IAEA standard water phantom. The ionisation chamber was inserted in the water phantom at a reference depth dependent on the type of the radiation quality used. Three radiation qualities were used namely 1.