7 results match your criteria: "Universitetskaya str. 33[Affiliation]"
The Degradation and Aging of Biological Systems as a Process of Information Loss and Entropy Increase.
Entropy (Basel)
July 2023
Laboratory of DNA-Protein Interactions, Engelhardt Institute of Molecular Biology of Russian Academy of Sciences, Vavilova Str. 32, 119991 Moscow, Russia.
Article Synopsis
- - The text examines the aging and degradation of biological organisms through the lens of statistical physics, focusing on two key timescales: metabolic processes and life cycles.
- - It proposes a kinetic equation to explain short-term processes in these systems and emphasizes the need for a constant input of negative entropy to keep biological systems stable.
- - The study includes an analysis of epithelial aging and discusses the relationship between this approach and information theory, including the concept of cooperons and their evolution over time.
A New Model of Hemoglobin Oxygenation.
Entropy (Basel)
August 2022
Laboratory of DNA-Protein Interactions, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova Str. 32, 119991 Moscow, Russia.
Article Synopsis
- The study explores how hemoglobin binds to oxygen, highlighting the cooperative nature of this process based on earlier works by Hill.
- The Adair model is noted for better fitting experimental data, though its parameter meanings are still not fully understood.
- The researchers improved upon Hill's approach by using a Lorentz distribution for oxygen partial pressure, resulting in a model that more accurately describes the experimental data than both the Hill and Adair equations.
The Use of the Statistical Entropy in Some New Approaches for the Description of Biosystems.
Entropy (Basel)
January 2022
Laboratory of DNA-Protein Recognition, Engelhardt Institute of Molecular Biology of Russian Academy of Sciences, Vavilova Str. 32, 119991 Moscow, Russia.
Article Synopsis
- * It highlights how cooperation among different parts of an organism reduces entropy, indicating that multicellular organisms have lower entropy compared to colonies of unicellular organisms.
- * A kinetic model of metabolism, aligning with Schrödinger's idea of "negentropy feeding," is introduced to calculate and compare local nonequilibrium entropy with equilibrium entropy found in non-living systems.
A Novel Nanoconjugate of Landomycin A with C Fullerene for Cancer Targeted Therapy: Studies.
Cell Mol Bioeng
February 2019
College of Pharmacy, University of Kentucky, South Limestone Str. 789, Lexington, 40536-0596 USA.
Introduction: Landomycins are a subgroup of angucycline antibiotics that are produced by bacteria and possess strong antineoplastic potential. Literature data suggest that enhancement of the therapeutic activity of this drug may be achieved by means of creating specific drug delivery systems. Here we propose to adopt C fullerene as flexible and stable nanocarrier for landomycin delivery into tumor cells.
View Article and Find Full Text PDFEffect of Nicotinamide on the Photolysis of Riboflavin in Aqueous Solution.
Sci Pharm
May 2016
Department of Physics, Sevastopol State University, Universitetskaya str. 33, Sevastopol 299053, Russia; Department of Biological and Chemical Sciences, Belgorod National Research University, Pobeda str. 85, Belgorod 308015, Russia.
The photolysis of riboflavin (RF) in aqueous solution in the presence of nicotinamide (NA) by visible light has been studied in the pH range 1.0-12.0 and the various photoproducts have been identified as known compounds.
View Article and Find Full Text PDFShape-independent model (SHIM) approach for studying aggregation by NMR diffusometry.
J Chem Phys
March 2015
Department of Biology and Chemistry, Belgorod State University, Belgorod 308015, Russia.
NMR diffusometry has been gaining wide popularity in various areas of applied chemistry for investigating diffusion and complexation processes in solid and aqueous phases. To date, the application of this method to study aggregation phenomena proceeding beyond the dimer stage of assembly has been restricted by the need for a priori knowledge of the aggregates' shape, commonly difficult to know in practice. We describe here a comprehensive analysis of aggregation parameter-dependency on the type and shape selected for modeling assembly processes, and report for the first time a shape-independent model (designated the SHIM approach), which may be used as an alternative in cases when information on aggregates' shapes is unavailable.
View Article and Find Full Text PDFRandom versus sequential pathway of molecular self-assembly.
Phys Rev E Stat Nonlin Soft Matter Phys
June 2012
Department of Physics, Sevastopol National Technical University, Universitetskaya str. 33, Sevastopol 99053, Ukraine.
Two important assumptions are often made in the analysis of molecular self-assembly at equilibrium, viz., that sequential is preferred to random aggregation and that the equilibrium constants at each stage of aggregation are equal, though both assumptions have not been justified strictly. In the present work we show that molecular self-assembly leading to formation of linear polymers and proceeding in a random manner appears to be less entropically favored than sequential aggregation, which provides a physical background for assuming sequential aggregation when studying molecular self-assembly in solution.
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