Associations between momentary mental states and concurrent social functioning after remission from first episode psychosis: A HAMLETT ecological momentary assessment study.

Background: Symptom severity and social functioning are important outcomes after first episode psychosis (FEP), yet current evidence about associations between them is inconsistent and lacks (subclinical) momentary insights.

Methods: The current Ecological Momentary Assessment (EMA) study was conducted in 58 people in remission from FEP, as part of the HAMLETT (Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment) trial. At baseline, participants were prompted to report momentary mental states and social context 10x/day for eight consecutive days, including psychotic experiences (PEs), motivation/drive and negative affect, that may indicate proxies of (subclinical) psychotic, negative and general affective symptoms, respectively.

The impact of dietary claims on behaviour: Expectations qualify how actual satiety affects cognitive performance.

Dietary choices significantly impact health and daily cognitive performance, prompting various recommendations for eating habits. Whereas much research has focused on the effects of actual satiety on cognitive performance, the influence of expectations regarding effects of satiety on performance remains underexplored. This study aims to address this gap by examining how the expectation of satiety influences cognitive outcomes, building on existing findings that highlight the role of placebo effects in shaping eating behaviour.

Investigating the impact of the effective point of measurement for plane-parallel ionization chambers in clinical proton beams.

To investigate the impact of the positioning of plane-parallel ionization chambers in proton beams on the calculation of the chamber-specific factor fand, hence, the beam quality correction factor k. Approach: Monte Carlo simulations were performed to calculate the chamber-specific factor fin monoenergetic proton beams for six different plane-parallel ionization chambers while positioning the chambers with a) their reference point and b) their effective point of measurement accounting for the water equivalent thickness of the entrance window. Main results: For all ionization chamber models investigated in this study, the difference in fbetween both positioning approaches was larger for steeper dose gradients and bigger differences between the geometrical thickness and water-equivalent thickness of the entrance window.

Can health impact assessment help tackle commercial determinants of health and support a wellbeing economy?

Commercial activity has positive and negative effects on health. Adverse commercial impacts on health are underpinned by corporate power and economic models and policy that prioritize economic growth, rather than a wellbeing economy that prioritizes health, equity and sustainability. Health in all policies (HiAP) aims to ensure that all policies promote health and health equity, using processes including health impact assessment (HIA).

EEG resting state alpha dynamics predict an individual's vulnerability to auditory hallucinations.

Unlabelled: Task-free brain activity exhibits spontaneous fluctuations between functional states, characterized by synchronized activation patterns in distributed resting-state (RS) brain networks. The temporal dynamics of the networks' electrophysiological signatures reflect individual variations in brain activity and connectivity linked to mental states and cognitive functions and can predict or monitor vulnerability to develop psychiatric or neurological disorders. In particular, RS alpha fluctuations modulate perceptual sensitivity, attentional shifts, and cognitive control, and could therefore reflect a neural correlate of increased vulnerability to sensory distortions, including the proneness to hallucinatory experiences.

Evaluating a German learning disorders platform using the RE-AIM framework.

In recent years, online platforms have made educational, medical, and other professional content easily accessible, but research evaluating such platforms is still scarce. The purpose of the current study is to evaluate LONDI, a German learning disorders platform. The platform offers scientifically based information for different user groups, and an algorithm-based help system that professionals can use to facilitate diagnosing and planning interventions.

Longitudinal changes in preschoolers' adiposity indicators according to compliance with 24-hour movement behavior guidelines: results from the ToyBox-study.

Background: There is a lack of studies evaluating longitudinal changes in adiposity indicators and the association with 24-hour movement behavior guidelines in preschoolers. Therefore, this study aimed to investigate associations between changes in Body Mass Index (BMI) z-scores, waist circumference and waist-to-height ratio, and compliance with the 24-hour movement behavior guidelines in three- to six-year-old children from a European sample.

Methods: In total, data from a European sample of 719 preschoolers (50.

Are symptoms in pathologic scars related to nerve function or density? A scoping review.

Background: Hypertrophic scars and keloids are forms of pathologic scarring that can give rise to pain and pruritus. The link between nerve function and nerve density and the symptoms in pathologic scars (PS) remains unclear.

Objective: We aim to assess current knowledge on nerve function and nerve density in PS, and to explore a possible association between alterations in sensibility/nerve density and pathologic scar symptoms.

Engineering of a bilayer antibacterial wound dressing from bovine pericardium and electrospun chitosan/PVA/antibiotics for infectious skin wounds management: An in vitro and in vivo study.

Tissue deterioration and post-injury infections are the primary cause of skin diseases. Tissue engineering has developed various synthetic and natural polymers to generate bioactive scaffolds that can closely replicate the natural extracellular matrix (ECM). Decellularized tissues have emerged as a potential solution for reconstructing cutaneous lesions due to their ability to preserve the intricate protein structure and provide essential functional domains for cellular differentiation.

Assessing diagnostic accuracy: F-FDG PET-CT scans in low-grade infection detection among post-traumatic long bone non-unions; a literature review and clinical data.

Introduction: The diagnosis of low-grade infection in post-traumatic long bone non-unions poses challenges due to the absence of clinical signs. This study aimed to review the available literature on the diagnostic accuracy of imaging techniques for low-grade infections and assess the diagnostic accuracy of F-FDG PET-CT scans for low-grade infection in post-traumatic long bone non-unions.

Methods: A mini-review was conducted using Pubmed in March 2024.

Leveraging Blood Components for 3D Printing Applications Through Programmable Ink Engineering Approaches.

This study proposes a tunable ink engineering methodology to allow 3D printing processability of highly bioactive but otherwise low-viscous and unprintable blood-derived materials. The hypothesis relies on improving the viscoelasticity and shear thinning behavior of platelet lysates (PL) and albumins (BSA) solutions by covalent coupling, enabling simultaneous extrusion and photocrosslinking upon filament deposition. The available amine groups on proteins (PL and BSA) are exploited for coupling with carboxyl groups present in methacrylated proteins (hPLMA and BSAMA), by leveraging carbodiimide chemistry.

A hybrid construct with tailored 3D structure for directing pre-vascularization in engineered tissues.

Hybrid 3D constructs combining different structural components afford unique opportunities to engineer functional tissues. Creating functional microvascular networks within these constructs is crucial for promoting integration with host vessels and ensuring successful engraftment. Here, we present a hybrid 3D system in which poly (ethylene oxide terephthalate)/poly (butylene terephthalate) fibrous scaffolds are combined with pectin hydrogels to provide internal topography and guide the formation of microvascular beds.

Semantic fMRI neurofeedback of emotions: from basic principles to clinical applications.

During fMRI neurofeedback participants learn to self-regulate activity in relevant brain areas and networks based on ongoing feedback extracted from measured responses in those regions. This closed-loop approach has been successfully applied to reduce symptoms in mood disorders such as depression by showing participants a thermometer-like display indicating the strength of activity in emotion-related brain areas. The hitherto employed conventional neurofeedback is, however, 'blind' with respect to emotional content, i.

Social networks and COVID-19 vaccination intention in Dutch middle-aged and older adults in 2020: Insights into individual, interpersonal, community, and societal determinants - The SaNAE study.

Background: Social networks, our social relationships, influence the spread of infectious diseases and preventive behaviors such as vaccination. Here, we aimed to assess which individual, interpersonal (social network characteristics), community and societal factors are associated with coronavirus disease 2019 (COVID-19) vaccination intention during the second wave of the COVID-19 pandemic in 2020, prior to vaccine availability.

Methods: This cross-sectional study collected primary data from 5,001 community-dwelling adults aged 40 years and older in the Netherlands, using an online questionnaire from August and November 2020.

The quantification of bone mineral density using photon counting computed tomography and its implications for detecting bone remodeling.

HR-pQCT has become standard practice when quantifying volumetric BMD (vBMD) in vivo. Yet, it is only accessible to peripheral sites, with small fields of view and lengthy scanning times. This limits general applicability in clinical workflows.

Diet and risk of atrial fibrillation: a systematic review.

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia. Comprehensive modification of established AF risk factors combined with dietary interventions and breaking deleterious habits has been shown to reduce AF burden and recurrence. Numerous AF risk factors, such as diabetes, obesity or hypertension can be partially related to dietary and lifestyle choices.

Combined portal and hepatic vein embolisation in perihilar cholangiocarcinoma.

Background: Major hepatectomy in perihilar cholangiocarcinoma (pCCA) patients with a small future liver remnant (FLR) risks posthepatectomy liver failure (PHLF). This study examines combined portal and hepatic vein embolisation (PVE/HVE) to increase preoperative FLR volume and potentially decrease PHLF rates.

Methods: In this retrospective, multicentre, observational study, data was collected from centres affiliated with the DRAGON Trials Collaborative and the EuroLVD registry.

First Results of Pediatric Robotic Inguinal Hernia Repair with the Senhance Surgical System: A Matched Cohort Study.

Introduction: Inguinal hernia repair (IHR) is one of the most common procedures in pediatric surgery. In children, the application of robotic surgery is limited, meaning safety and efficacy is still to be assessed. This report is the first one worldwide that describes inguinal hernia repair in children using the Senhance Surgical System (SSS).

Modelling methacrylated chitosan hydrogel properties through an experimental design approach: from composition to material properties.

Hydrogels of biopolymers are gradually substituting synthetic hydrogels in tissue engineering applications due to their properties. However, biopolymeric hydrogels are difficult to standardize because of the intrinsic variability of the material and the reversibility of physical crosslinking processes. In this work, we synthesized a photocrosslinkable derivative of chitosan (Cs), namely methacrylated chitosan (CsMA), in which the added methacrylic groups allow the formation of hydrogels through radical polymerization triggered by UV exposure.

Analysis of re-recurrent rectal cancer after curative treatment of locally recurrent rectal cancer.

Purpose: Substantiating data guiding clinical decision making in locally recurrent rectal cancer (LRRC) is lacking, specifically in target volume (TV) definition for chemoradiotherapy (CRT). A case-by-case review of local re-recurrences (re-LRRC) after multimodal treatment for LRRC was performed, to determine location of re-LRRC and assess whether treatment could have been improved.

Methods: All patients treated with curative intent for LRRC at the Catharina Hospital Eindhoven from October 2016 onwards, in whom complete imaging of (re-)LRRC and radiotherapy was available, were retrieved.