2,903 results match your criteria: "Universite de Lausanne[Affiliation]"

During the investigation of firearm-related incidents, gunshot residues (GSR) can be collected on the scene and individuals (e.g., shooters or bystanders).

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Artificial selection is a promising way to improve microbial community functions, but previous experiments have only shown moderate success. Here, we experimentally evaluate a new method that was inspired by genetic algorithms to artificially select small bacterial communities of known species composition based on their degradation of an industrial pollutant. Starting from 29 randomly generated four-species communities, we repeatedly grew communities for four days, selected the 10 best-degrading communities, and rearranged them into 29 new communities composed of four species of equal ratios whose species compositions resembled those of the most successful communities from the previous round.

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Trust, trustworthiness and AI governance.

Sci Rep

September 2024

Information Science and Media Studies, Universitetet I Bergen, 5007, Bergen, Norway.

An emerging issue in AI alignment is the use of artificial intelligence (AI) by public authorities, and specifically the integration of algorithmic decision-making (ADM) into core state functions. In this context, the alignment of AI with the values related to the notions of trust and trustworthiness constitutes a particularly sensitive problem from a theoretical, empirical, and normative perspective. In this paper, we offer an interdisciplinary overview of the scholarship on trust in sociology, political science, and computer science anchored in artificial intelligence.

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is an emerging pathogen that poses a significant challenge due to its multidrug-resistant nature. There are two types of antifungal agents, fungicidal and fungistatic, with distinct mechanisms of action against fungal pathogens. Fungicidal agents kill fungal pathogens, whereas fungistatic agents inhibit their growth.

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[Not Available].

Rev Med Suisse

August 2024

Vice-directrice médicale, formation et relève, Centre hospitalier universitaire vaudois, Directrice a.i. de l'École de formation postgraduée médicale, Faculté de biologie et de médecine, Université de Lausanne.

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[Not Available].

Rev Med Suisse

August 2024

Étudiante en 4e année de médecine, Faculté de médecine, Université de Lausanne, 1015 Lausanne.

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Article Synopsis
  • The COVID-19 pandemic has severely impacted immunosuppressed individuals, such as solid organ transplant recipients and those undergoing cancer treatment, leading to worse health outcomes and higher mortality rates.
  • Due to challenges in studying these vulnerable populations, researchers created a mathematical model to simulate immune responses and analyzed virtual patient cohorts that mirrored clinical data from cancer and immunosuppressed patients.
  • The model revealed that severe cases in these groups exhibited reduced CD8+ T cells, delayed type I interferon peaks, and higher tissue damage, suggesting that immune dysfunction is a critical factor in COVID-19 severity for cancer patients.
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Background: Physical activity referral schemes (PARS) are composed of various components, such as a written prescription or a person-centered approach. The role of these components in their effectiveness is yet to be understood. Therefore, we aimed to explore the relationships between PARS components and physical activity, scheme uptake, and adherence rate; and to estimate the effect of PARS.

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Recently, a variety of technical approaches in world-class pole-vaulters' behaviour have been observed. The aim of this study was to investigate the presence of subgroups using different technical approaches and to compare biomechanical performance differences. Biomechanical analysis of performances over 5.

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Differentiation of five forensically relevant body fluids using a small set of microRNA markers.

Electrophoresis

October 2024

Unité de Génétique Forensique, Centre Universitaire Romand de Médecine Légale, Centre Hospitalier Universitaire Vaudois et Université de Lausanne, Lausanne, Switzerland.

In forensic investigations, identifying the type of body fluid allows for the interpretation of biological evidence at the activity level. Over the past two decades, significant research efforts have focused on developing molecular methods for this purpose. MicroRNAs (miRNAs) hold great promise due to their tissue-specific expression, abundance, lack of splice variants, and relative stability.

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Post-mortem recrystallization of biogenic amorphous calcium carbonate guided by the inherited macromolecular framework.

Sci Rep

July 2024

Laboratory for Biological Geochemistry, School of Architecture, Civil and Environmental Engineering (ENAC), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

In contrast to abiotically formed carbonates, biogenetic carbonates have been observed to be nanocomposite, organo-mineral structures, the basic build-blocks of which are particles of quasi-uniform size (10-100 nm) organized into complex higher-order hierarchical structures, typically with highly controlled crystal-axis alignments. Some of these characteristics serve as criteria for inferring a biological origin and the state of preservation of fossil carbonate materials, and to determine whether the biomineralization process was biologically induced or controlled. Here we show that a calcium storage structure formed by the American lobster, a gastrolith initially consisting of amorphous calcium carbonate (ACC) and amorphous calcium phosphate (ACP), post-mortem can crystallize into (thus secondary) calcite with structural properties strongly influenced by the inherited organic matrix.

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The effect of helminthiasis on host immunity is a neglected area of research, particularly in tuberculosis (TB) infection. This study aimed to evaluate the effect of helminthiasis on immunological and haematological parameters in newly diagnosed TB patients in Bobo-Dioulasso. After all biological analyses, we formed three subpopulations: group 1 ( = 82), as control, were participants without helminthic or complex infection (-/Helm-), group 2 ( = 73) were TB patients without helminthic infection (+/Helm-), and group 3 ( = 22) were TB patients with helminthic infection (+/Helm+).

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Single-particle tracking techniques enable investigation of the complex functions and interactions of individual particles in biological environments. Many such techniques exist, each demonstrating trade-offs between spatiotemporal resolution, spatial and temporal range, technical complexity, and information content. To mitigate these trade-offs, we enhanced a confocal laser scanning microscope with an asynchronous read-out single-photon avalanche diode array detector.

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Older employees often face discrimination and exclusion from work teams. In two scenario studies, we tested the impact of age diversity statements on the representation and inclusion of older employees in teams. In Study 1 ( = 304), participants had to create a team and were either exposed to a diversity statement or not before selecting two teammates from a list of four differing in age and gender.

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[Not Available].

Can J Psychiatry

October 2024

Département d'éducation et pédagogie, counseling de carrière, Université du Québec à Montréal (UQAM), Centre de recherche de l'Institut Universitaire en Santé Mentale de Montréal (CR-IUSMM), Montréal, Canada.

Objective: There are few tools capable of measuring the personal recovery of individuals presenting with mental disorders that take into account the various dimensions of recovery. Personal recovery encompasses several objectives at the level of autonomy, positive interpersonal relationships, mental and physical health, self-acceptance, the school/professional domain, as well as developing a life project. A team of practitioners and researchers from four countries (Canada, Belgium, France, and Switzerland) adapted the Client Assessment of Strengths, Interests, and Goals (CASIG) tool to more accurately measure these different aspects of personal recovery.

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[Exercise addiction].

Rev Med Suisse

July 2024

Département de médecine du sport, Swiss Olympic Medical Center, Centre hospitalier universitaire vaudois, 1011 Lausanne.

Exercise addiction, although not yet officially recognized, can be defined as the harmful practice of physical exercise, described as a compulsive need, where damage take precedence over the benefits of this practice, with a continuation of this behavior despite the negative consequences. A number of risk factors have been identified, including psychopathological conditions such as eating disorders or other addictions. It is possible to detect this addiction and assess its intensity using multidimensional questionnaires, even the clinical relevance and thresholds of which are still debated.

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[Not Available].

Rev Med Suisse

July 2024

Centre de médecine du sport, Swiss Olympic Medical Center, Division de médecine physique et réadaptation, Département de l'appareil locomoteur, Centre hospitalier universitaire vaudois, Lausanne.

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To quantify selection acting on a trait, methods have been developed using either within or between-species variation. However, methods using within-species variation do not integrate the changes at the macro-evolutionary scale. Conversely, current methods using between-species variation usually discard within-species variation, thus not accounting for processes at the micro-evolutionary scale.

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Traditional theories of motor learning emphasize the automaticity of skillful actions. However, recent research has emphasized the role of pre-reflective self-consciousness accompanying skillful action execution. In the present paper, we present the course-of-experience framework as a means of studying elite athletes' pre-reflective self-consciousness in the unfolding activity of performance optimization.

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Towards an informed research agenda for the field of personality disorders by experts with lived and living experience and researchers.

Borderline Personal Disord Emot Dysregul

July 2024

Department of Clinical Psychology and Psychotherapy, Freie Universität Berlin, Habelschwerdter Allee 45, 14195, Berlin, Germany.

Background: We describe a collection of themes for a research agenda for personality disorders that was originally formulated for the ESSPD Borderline Congress in 2022.

Methods: Experts with lived and living experience (EE), researchers and clinicians met virtually, exchanged ideas and discussed research topics for the field of personality disorders. The experts - patients, relatives, significant others - named the topics they thought most relevant for further research in the field.

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[Not Available].

Rev Med Suisse

July 2024

Plateforme Durabilité Santé, Centre de compétences en durabilité et Faculté de biologie et médecine, Université de Lausanne, 1011 Lausanne.

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[Colorectal cancer screening program in the canton of Vaud: raising awareness].

Rev Med Suisse

July 2024

Département des policliniques, Unisanté, Centre universitaire de médecine générale et santé publique, Université de Lausanne, 1011 Lausanne.

After five years of deployment, the participation rate in the Vaud colorectal cancer (CRC) screening program remains below projected targets. It was found that the communication tools made available to the population did not provide explicit recommendations regarding how to participate. To this end, Unisanté led a project between 2022 and 2023 to increase awareness and widely disseminate tools specifically designed with the target population.

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[Not Available].

Rev Med Suisse

July 2024

Institut de droit de la santé, Faculté de droit, Université de Neuchâtel, Swiss School of Public Health (SSPH+), Zurich.

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The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD.

Adv Sci (Weinh)

September 2024

Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11 Mandalay Road, Singapore, 308232, Singapore.

Article Synopsis
  • Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health issue, prompting a need for accurate preclinical models to study it.
  • The liver disease progression aggravation diet (LIDPAD) is a new murine model that mimics human MASLD closely, showing significant similarities in disease features and progression within weeks.
  • This model demonstrates responsiveness to dietary changes, making it valuable for researching therapeutic strategies while revealing important interactions between gut health and liver disease.
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