119 results match your criteria: "Universite Paul Verlaine-Metz[Affiliation]"
Naturwissenschaften
April 2009
Laboratoire des Interactions Ecotoxicologie, Biodiversité, Ecosystèmes (LIEBE), Université Paul Verlaine-Metz, UMR CNRS 7146, Campus Bridoux, 57070, Metz, France.
Manipulative parasites are known to alter the spatial distribution of their intermediate hosts in a way that enables trophic transmission to definitive hosts. However, field data on the ecological implications of such changes are lacking. In particular, little is known about the spatial coexistence between infected prey and dead-end predators after a parasite-induced habitat shift.
View Article and Find Full Text PDFJ Chem Phys
November 2008
Universite Paul Verlaine-Metz, Labo: LPMD, 1 Bd Arago, 57078 Metz, France.
We report optical characterization of silicon nanocrystals embedded in silica thin films by spectroscopic ellipsometry (SE). Silicon nanocrystals (nc-Si) are produced by single energy ion implantation and multienergy Si(+) ion implantation into 250 nm of thermal oxide (SiO(2)) layers on silicon substrate. After thermal annealing, the obtained nc-Si have a Gaussian and uniform profiles for single and multienergy implantation, respectively.
View Article and Find Full Text PDFChemosphere
December 2008
Laboratoire Interactions Ecotoxicologie, Biodiversité, Ecosystèmes, CNRS UMR 7146, Université Paul Verlaine-Metz, Metz, France.
The present paper investigated the short-term colonization by plants of a highly degraded soil in field conditions. The objectives were to identify, through phytosociological analysis, the plant species able to grow on such polluted areas and to characterize pollutant effects at different biological levels through analyses of plant oxidative status, plant growth or community indexes of richness and biodiversity. Our results showed that among the plants present in the uncontaminated surrounding area, only few species were able to colonize the polluted soil.
View Article and Find Full Text PDFUltrason Sonochem
February 2009
Laboratoire de Chimie et de Méthodologies pour l'Environnement, EA 4164, Université Paul Verlaine - Metz, 1 Bd Arago, Metz Technopôle, F-57078 Metz, Cedex 3, France.
Carboxylic acids and diacids were synthesized from monoenic fatty acids by using RuO4 catalysis, under ultrasonic irradiation, in various mixtures of solvents. Ultrasound associated with Aliquat 336 have promoted in water, the quantitative oxidative cleavage of the CH=CH bond of oleic acid. A design of experiment (DOE) shows that the optimal mixture of solvents (H2O/MeCN, ratio 1/1, 2.
View Article and Find Full Text PDFChemMedChem
November 2008
Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique, FR CNRS 2843, Université Paul Verlaine-Metz, Rue du Général Delestraint, 57070 Metz, France.
Chemosphere
September 2008
Université Paul Verlaine-Metz, Laboratoire "Interactions Ecotoxicologie, Biodiversité, Ecosystèmes", CNRS UMR 7146, Campus Bridoux, Rue du Général Delestraint, 57070 Metz, France.
The detoxification mechanisms of the aquatic moss, Fontinalis antipyretica Hedw., exposed to Cr was analyzed. In addition, the influence of Cr salts (as Cr nitrate, chloride and potassium bichromate) on these mechanisms has also been studied.
View Article and Find Full Text PDFToxicol In Vitro
September 2008
Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique, Université Paul Verlaine-Metz, Institut Jean Barriol FR CNRS 2843, Rue du Général Delestraint, Metz, France.
Depending on the strength of oxidative stress, cells exhibit proliferative, apoptotic or necrotic responses. We have investigated whether the severity of glutathione (GSH) depletion could determine the type of cell death using 1,4-benzoquinone (BQ) and H(2)O(2) in two different tumor cell lines (human mammary gland carcinoma MCF-7 and rat hepatoma H5-6). BQ-treated surviving cells showed an increase in GSH, but no detectable oxidized glutathione (GSSG) nor reactive oxygen species (ROS) augmentation.
View Article and Find Full Text PDFOpt Express
June 2008
Laboratoire de Physique des Milieux Denses, Universite Paul Verlaine - Metz, 1 Boulevard Arago CP 87811, F-57078 METZ Cedex 3, France.
The characterization of anisotropic materials and complex systems by ellipsometry has pushed the design of instruments to require the measurement of the full reflection Mueller matrix of the sample with a great precision. Therefore Mueller matrix ellipsometers have emerged over the past twenty years. The values of some coefficients of the matrix can be very small and errors due to noise or systematic errors can induce distored analysis.
View Article and Find Full Text PDFRev Epidemiol Sante Publique
July 2008
Erase, laboratoire lorrain de sciences sociales, université Paul-Verlaine-Metz, Ile du Saulcy, B.P. 30309, 57006 Metz cedex 1, France.
Background: While designed to help physicians in their account of the changing state of the art and of the evidence-based medicine, the situation of the medical guidelines seem to be critical: they need time, they are too complex, they deal with pathologies as if they were isolated from the whole context.
Methods: In the survey, 279 general practioners were asked to answer a scenario dealing with these difficulties.
Results: More than a half of the practitioners interviewed approve the increasing role of guidelines in medical practice and say they try to take them into account, but they also say they generally rely on their own medical experience to operate a selection among the impressive set of guidelines they receive.
Chemosphere
June 2008
Université Paul Verlaine Metz, Laboratoire Interactions Ecotoxicologie, Biodiversité, Ecosystèmes (LIEBE), CNRS UMR 7146, Campus Bridoux, Metz, France.
In order to enlarge the range of potential sentinel species for the implementation of a multiple biomarker approach, spatial and monthly morphological variations of four cellular compartments and contents were assessed during two years in the hepatopancreatic caeca of the freshwater gammarid, Dikerogammarus villosus (Crustacea, Amphipoda), using histochemistry coupled to image analysis. Among the three study sites, the second one, located in a reservoir receiving the overheated and copper-contaminated waters of a nuclear power plant, was the most anthropised. During this passive biomonitoring survey, unsaturated neutral lipids were more abundant, the surface densities of the lysosomal and peroxisomal systems were, respectively less and more important, and lipofuscin granules tended to accumulate in the amphipods from the second site compared to both others.
View Article and Find Full Text PDFParasitology
July 2008
Université Paul Verlaine-Metz, Laboratoire des Interactions Ecotoxicologie, Biodiversité, Ecosystèmes (LIEBE), CNRS UMR 7146, Campus Bridoux, rue du général Delestraint, F-57070 Metz, France.
Among the potential effects of parasitism on host condition, the 'increased host abilities' hypothesis is a counterintuitive pattern which might be predicted in complex-life-cycle parasites. In the case of trophic transmission, a parasite increasing its intermediate host's performance facing non-host predators improves its probability of transmission to an adequate, definitive host. In the present study, we investigated the cost of infection with the acanthocephalan Polymorphus minutus on the locomotor/escape performance of its intermediate host, the crustacean Gammarus roeseli.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
February 2008
Laboratoire de Physique et Mécanique des Matériaux, UMR CNRS No 7554, Université Paul Verlaine - Metz, Ile du Saulcy, 57045 Metz Cedex, France.
The unstable plastic flow of an AlMg alloy, associated with the Portevin-Le Chatelier effect, was studied near the lower strain-rate boundary of instability using multifractal analysis. Self-similarity of deformation curves, indicating long-range time correlations of stress serrations, was detected within the strain-rate range where serrations are commonly ascribed to the occurrence of uncorrelated deformation bands. The deformation curves display a wide range of shapes that are characterized by different groupings of serrations.
View Article and Find Full Text PDFJ Phys Condens Matter
March 2008
Laboratoire de Physique des Milieux Dense, Institut de Chimie, Physique et Matériaux, Université Paul Verlaine-Metz, 1 Bd Arago, 57078 Metz cedex 3, France.
We recall definitions of the electronic transport properties, direct coefficients like electrical and thermal transport conductivities and crossed thermoelectric coefficients like the Seebeck, Peltier and Thomson coefficients. We discuss the links between the different electronic transport coefficients and the experimental problems in measuring these properties in liquid metals. The electronic transport properties are interpreted in terms of the scattering of electrons by 'pseudo-atoms'.
View Article and Find Full Text PDFPhys Med Biol
February 2008
Université Paul Verlaine-Metz, Laboratoire de Physique Moléculaire et des Collisions, ICPMB (FR CNRS 2843), Institut de Physique, Metz Cedex 3, France.
A classical trajectory model has been used to predict total cross sections of single and double ionizing processes (including capture processes) for several ion-biological molecule collisional systems in the intermediate and high energy range. In this work, the systems studied are water, adenine or cytosine targets ionized by protons and alpha-particles with kinetic energies ranging from 25 keV amu(-1) to 3000 keV amu(-1). In our approach, we have combined several features of two classical methods namely the classical trajectory Monte Carlo (CTMC) and the classical over-barrier (COB) models.
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
April 2008
Laboratoire de Spectrométrie de Masse et de Chimie Laser, Université Paul Verlaine-Metz, Metz, France.
Laser ablation of transition-metal oxides have been investigated to better understand the formation processes of inorganic cluster ions. The study of binary oxide mixtures and the relative distribution of the ions produced suggest three salient mechanisms that occur after laser/matter interaction, that function to produce the observed ensemble of ionic species. Molecular recombination reactions, unimolecular dissociation processes, emission of small neutrals, including molecular oxygen from transition-metal oxide samples, or from species expelled in gas phase appear to be a significant mechanism, especially under high laser irradiance conditions.
View Article and Find Full Text PDFMicrob Ecol
August 2008
Laboratoire Interactions Ecotoxicité, Biodiversité, Ecosystèmes, UMR CNRS 7146, Université Paul Verlaine-Metz, Délestraint, 57070, Metz, France.
Aquatic hyphomycetes play an essential role in the decomposition of allochthonous organic matter which is a fundamental process driving the functioning of forested headwater streams. We studied the effect of anthropogenic acidification on aquatic hyphomycetes associated with decaying leaves of Fagus sylvatica in six forested headwater streams (pH range, 4.3-7.
View Article and Find Full Text PDFLife Sci
January 2008
Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique, FR CNRS 284, UFR SciFA, Université Paul Verlaine-Metz, Campus Bridoux, rue du Général Delestraint, 57070 Metz, France.
Dual-specific phosphatases Cdc25 play a critical role in the cell cycle regulation by activating kinases of Cdk/cyclin complexes. Three Cdc25 isoforms (A, B and C) have been identified in mammalians. Cdc25A and B display oncogenic properties and are over-expressed in different tumors.
View Article and Find Full Text PDFBioorg Med Chem Lett
February 2008
Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique, Université Paul Verlaine - Metz, Institut Jean Barriol FR CNRS 2843, UFR SciFA, Campus Bridoux, rue du Général Delestraint, 57070 Metz, France.
The use of doxorubicin (DOX) in the treatment of solid tumors is limited by cardiotoxicity essentially due to oxidative stress generation. The aim of this study was to identify coumarin derivatives displaying a protective antioxidant activity without affecting DOX antitumoral efficiency. A set of eighteen coumarinic derivatives was synthesized.
View Article and Find Full Text PDFJ Nucl Med
January 2008
Laboratoire de Physique Moléculaire et des Collisions, Université Paul Verlaine-Metz, Institut de Physique, Metz, France.
Unlabelled: Monte Carlo simulation can be particularly suitable for modeling the microscopic distribution of energy received by normal tissues or cancer cells and for evaluating the relative merits of different radiopharmaceuticals. We used a new code, CELLDOSE, to assess electron dose for isolated spheres with radii varying from 2,500 mum down to 0.05 mum, in which (131)I is homogeneously distributed.
View Article and Find Full Text PDFPhys Rev Lett
October 2007
Laboratoire de Physique et Mécanique des Matériaux, Université Paul Verlaine-Metz/CNRS, Ile du Saulcy, 57045 Metz Cedex, France.
Single crystals of ice subjected to primary creep in torsion exhibit a softening behavior: the plastic strain rate increases with time. In a cylindrical sample, the size of the radius affects this response. The smaller the radius of the sample becomes while keeping constant the average shear stress across a section, the softer the response.
View Article and Find Full Text PDFPhys Med Biol
November 2007
Laboratoire de Physique Moléculaire et des Collisions, ICPMB (FR 2843), Institut de Physique, Université Paul Verlaine-Metz, 1 boulevard Arago, 57078 Metz Cedex 3, France.
With the increasing development of positron emission tomography (PET), beta(+)-emitters are more and more regularly used in nuclear medicine. Therefore, today it is of prime importance to have a reliable description of their behavior in living matter in order to quantify the full spectra of the molecular damages potentially radio-induced and then to access a cellular dosimetry. In this work, we present a detailed inter-comparison of the main isotopes commonly used in PET: (18)F, (11)C, (13)N, (15)O, (68)Ga and (82)Rb.
View Article and Find Full Text PDFDrug Metab Dispos
February 2008
Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique, Institut Jean Barriol FR Centre National de la Recherche Scientifique 2843, Université Paul Verlaine-Metz, Metz, France.
Carboxylic acid-containing drugs are metabolized mainly through the formation of glucuronide and coenzyme A esters. These conjugates have been suspected to be responsible for the toxicity of several nonsteroidal anti-inflammatory drugs because of the reactivity of the electrophilic ester bond. In the present study we investigated the reactivity of ketoprofenyl-acylglucuronide (KPF-OG) and ketoprofenyl-acyl-coenzyme A (KPF-SCoA) toward cytosolic rat liver glutathione S-transferases (GST).
View Article and Find Full Text PDFJ Microsc
September 2007
Laboratoire d'Etude des Textures et d'Application des Matériaux, UMR CNRS 7078, Université Paul Verlaine - Metz, Ile du Saulcy, F-57012 Metz, France.
The question of the statistical accuracy of EBSD data for global texture calculation was re-explored on the basis of a very large grain population (83 000 grains measured on a recrystallized low-alloyed Zr sheet). Previous works aimed mainly at identifying and quantifying the main texture components and were based on much smaller data sets. The present work attempts to quantify the accuracy of the complete texture, including low-density regions of the orientation space.
View Article and Find Full Text PDFMutat Res
October 2007
Laboratoire LIEBE UMR 7146 CNRS, Université Paul Verlaine Metz, rue du General Delestraint, 57070 Metz, France.
This study investigates different effects in roots of Vicia faba (broad bean) after exposure to cadmium. Genotoxic effects were assessed by use of the well-known Vicia root tip micronucleus assay. Cytotoxic effects were evaluated by determining the mitotic index in root tip cells.
View Article and Find Full Text PDFAnal Bioanal Chem
November 2007
Laboratoire de Spectrométrie de Masse et de Chimie Laser, Université Paul Verlaine - Metz, 1, Boulevard Arago, 57078 Metz Technopole Cedex 03, France.
The combination of a laser with a Fourier transform ion cyclotron resonance mass spectrometer (FTICRMS) enables a variety of MS experiments to be conducted. The laser can be used either as an intense photonic source for the photoionization of neutral species introduced in a variety of ways into the FTICR cell, or it can be made to directly interact with a solid, generating gas-phase ions. Depending on the experimental conditions used, various laser-matter interactions can occur.
View Article and Find Full Text PDF