Pseudotumoral calcinosis of the elbow with ulnar and radial nerve deficits.

We report here a rare case of an acute peripheral nerve compression by pseudotumoral calcinosis (PCT) at the right elbow in a patient with severe tertiary hyperaparathyroidism. This complication required urgent multidisciplinary management. Surgical decompression by PCT resection enabled rapid motor and sensory recovery.

Comparison of false starts by saw created on flesh and dry bones; as close as possible to the real conditions of criminal dismemberment.

In most experimental protocols, false starts are produced on dry bones obtained through a maceration process for anthropological analyses, for the sake of reproducibility. Although this allows for controlled experimental conditions, the absence of soft parts when experimentally creating false starts does not correspond to the real conditions of criminal dismemberment. The main objective of this study was to determine if the results of experimental work on the characteristics of false starts were valid under medico-legal conditions.

A national survey to assess the state of anatomy teaching in France across various disciplines and professions.

Purpose: To investigate the current practices in anatomy teaching at French universities in 2023.

Methods: On January 10, 2023, a questionnaire was sent to all members of the official list of the French Medical College of Professors of Anatomy. Each Anatomy centre was asked to complete this online form only once.

When can a population spreading across sink habitats persist?

We consider populations with time-varying growth rates living in sinks. Each population, when isolated, would become extinct. Dispersal-induced growth (DIG) occurs when the populations are able to persist and grow exponentially when dispersal among the populations is present.

An Atypical Case of Microscopic Polyangiitis Associated With Myelodysplastic Syndrome and Complete Atrioventricular Block Mistaken for Infectious Pneumonia.

The association between antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis and hematologic malignancy has been previously described and remains a rare phenomenon (although potentially underdiagnosed). We report the case of an 81-year-old patient with myelodysplastic syndrome who was managed for an infectious-appearing pneumonia, which subsequently complicated into complete heart block and severe acute respiratory distress syndrome with a fatal outcome. The final diagnosis is severe hemorrhagic alveolitis due to ANCA-associated vasculitis meeting the criteria for microscopic polyangiitis.

Untangling the role of temporal and spatial variations in persistence of populations.

We consider a population distributed between two habitats, in each of which it experiences a growth rate that switches periodically between two values, 1-ɛ>0 or -(1+ɛ)<0. We study the specific case where the growth rate is positive in one habitat and negative in the other one for the first half of the period, and conversely for the second half of the period, that we refer as the (±1) model. In the absence of migration, the population goes to 0 exponentially fast in each environment.

A network embedding approach to identify active modules in biological interaction networks.

The identification of condition-specific gene sets from transcriptomic experiments is important to reveal regulatory and signaling mechanisms associated with a given cellular response. Statistical methods of differential expression analysis, designed to assess individual gene variations, have trouble highlighting modules of small varying genes whose interaction is essential to characterize phenotypic changes. To identify these highly informative gene modules, several methods have been proposed in recent years, but they have many limitations that make them of little use to biologists.

Pressure and folding effects on the buckling of a freestanding compressed thin film.

The combined effects of compressive stress, applied pressure, and edge folding of a freestanding thin film have been theoretically investigated on the buckle morphologies of the structure. In the framework of the Föppl-von Kármán theory of thin plates, the different buckle profiles have been analytically determined, and two buckling regimes have been identified for the film: one regime where the transition from upward to downward buckling is continuous, and one that is discontinuous (snap-through). The critical pressures characterizing the different regimes have then been determined, and an hysteresis cycle has been identified through the study of buckling versus pressure.

Multidisciplinary peer-led sexual and reproductive health education programme in France, a prospective controlled-study.

Background: Sexual education is an international priority to promote sexual and reproductive health (SRH) and to reduce risky sexual behaviour. Experts recommend holistic and comprehensive SRH peer-led education. In 2018, the French government launched a new public peer-led health prevention programme called the "Service Sanitaire" (SeSa), consisting of health education provided by healthcare students (peer educators) to teenagers.

Experimental Investigation of Dental Composites Degradation After Early Water Exposure.

While dental composite long-term aging has already been studied in the past, no data exist about the early aging while it might be detrimental regarding the composites' longevity. This study aims to better understand the effects of early water exposure on dental composites. Dental resin composites with different fillers ratio were subjected to water exposure during 24 h, 1 week, or 1 month.

Comparison of microscopic features of bone false starts produced by reciprocating saw blades and handsaws of the same class.

In cases of criminal dismemberment, the analysis of saw marks helps to determine the class of the saw used. The present study compared the microscopic features of experimental false starts performed on three freshly defleshed human femurs. 150 lesions were produced using three reciprocating blades and two hand saws of similar class.

Modern and synchronized clinical anatomy teaching based on the BDIE method (board-digital dissection-imaging-evaluation).

Purpose: Anatomy has historically been taught via traditional medical school lectures and dissection. In many countries, practical or legal issues limit access to cadaveric dissection. New technologies are favored by students and could improve learning, complementing traditional teaching.

Origin and mobility of Iron Age Gaulish groups in present-day France revealed through archaeogenomics.

The Iron Age period occupies an important place in French history because the Gauls are regularly presented as the direct ancestors of the extant French population. We documented here the genomic diversity of Iron Age communities originating from six French regions. The 49 acquired genomes permitted us to highlight an absence of discontinuity between Bronze Age and Iron Age groups in France, lending support to a cultural transition linked to progressive local economic changes rather than to a massive influx of allochthone groups.

A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains.

Toxin-antitoxin (TA) gene pairs are ubiquitous in microbial chromosomal genomes and plasmids as well as temperate bacteriophages. They act as regulatory switches, with the toxin limiting the growth of bacteria and archaea by compromising diverse essential cellular targets and the antitoxin counteracting the toxic effect. To uncover previously uncharted TA diversity across microbes and bacteriophages, we analyzed the conservation of genomic neighborhoods using our computational tool FlaGs (for flanking genes), which allows high-throughput detection of TA-like operons.

Relationship between the oxidative status and the tumor growth in transplanted triple-negative 4T1 breast tumor mice after oral administration of rhenium(I)-diselenoether.

Background: Selective inhibitory effects of rhenium(I)-diselenoether (Re-diSe) were observed in cultured breast malignant cells. They were attributed to a decrease in Reactive Oxygen Species (ROS) production. A concomitant decrease in the production of Transforming Growth Factor-beta (TGFβ1), Insulin Growth Factor 1 (IGF1), and Vascular Endothelial Growth Factor A (VEGFA) by the malignant cells was also observed.

Musca domestica (Diptera: Muscidae) as a biological model for the assessment of magnetite nanoparticles toxicity.

The use of nanoparticles (NPs) is rapidly expanding; there is a critical need for efficient assays to first determine the potential toxicity of NPs before their use in human applications. Magnetite nanoparticles (FeO NPs) have tremendous applications which include cell separation, arsenic removal from water and DNA separation. Spherically shaped FeO NPs with sizes ranging from 23 to 30 nm were used in this study.

Use of Blue and Blue-Violet Lasers in Dentistry: A Narrative Review.

Blue and blue-violet diode lasers (450 and 405 nm) seem to represent an interesting approach for several clinical treatments today. The aim of this narrative review is to describe and comment on the literature regarding the utilization of blue and blue-violet lasers in dentistry. A search for "blue laser AND dentistry" was conducted using the PubMed database, and all the papers referring to this topic, ranging from 1990 to April 2020, were analyzed in the review.

Assessing and promoting partnership between patients and health-care professionals: Co-construction of the CADICEE tool for patients and their relatives.

Context: Partnership between patients and health-care professionals (HCPs) is a concept that needs a valid, practical measure to facilitate its use by patients and HCPs.

Objective: To co-construct a tool for measuring the degree of partnership between patients and HCPs.

Design: The CADICEE tool was developed in four steps: (1) generate key dimensions of patient partnership in clinical care; (2) co-construct the tool; (3) assess face and content validity from patients' and HCPs' viewpoints; and (4) assess the usability of the tool and explore its measurement performance.

Comparison of 15 dinoflagellate genomes reveals extensive sequence and structural divergence in family Symbiodiniaceae and genus Symbiodinium.

Background: Dinoflagellates in the family Symbiodiniaceae are important photosynthetic symbionts in cnidarians (such as corals) and other coral reef organisms. Breakdown of the coral-dinoflagellate symbiosis due to environmental stress (i.e.

[Osteoporosis treatment].

Osteoporosis treatment. Osteoporosis treatment is a public health issue that requires a comprehensive approach combining drugs and lifestyle measures. Lifestyle measures (nutrition, prevention of falls, etc.

A numerical, theoretical and experimental study of the effect of thermocycling on the matrix-filler interface of dental restorative materials.

Objective: Thermocycling is widely used to age dental composites but with very different results from one study to another, even with apparent similar conditions. This study aims at understanding better the relative damaging speed of matrix and fillers, based on theoretical models.

Methods: Eight formulations of an experimental dental material were produced.