3,773 results match your criteria: "Universite Bordeaux[Affiliation]"

Triply phenanthryl- and tetrahelicenyl-substituted triazine-hexaalkyl esters with short alkyl chains show glass transitions conveniently above room temperature within the hexagonal columnar liquid crystalline state, resulting in a solid columnar order at room temperature. As the hexagonal columnar mesophase is easily aligned with the director perpendicular to a solid substrate, such glassy columnar liquid matrices are aimed at for the orientation of guest emitters, to obtain anisotropic emission. A condition for face-on alignment on substrates are attainable melting and clearing temperatures, which is achieved with the moderately nonplanar tetrahelicenyl derivatives in spite of their short alkyl periphery.

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Room Temperature Phosphorescence in Solution from Thiophene-Bridged Triply Donor-Substituted Tristriazolotriazines.

Chemistry

April 2023

Departamento de Química, Universidade Federal de Santa Catarina Trindade, 88040-900, Florianópolis, SC, Brazil.

Most organic room-temperature phosphorescence (RTP) emitters do not show their RTP in solution. Here, we incorporated sulfur-containing thiophene bridges between the donor and acceptor moieties in D A-type tristriazolotriazines (TTTs). The thiophene inclusion increased the spin-orbit coupling associated with the radiative T →S pathway, allowing RTP to be observed in solution for all compounds, likely assisted by protection of the emissive TTT-thiophene core from the environment by the bulky peripheral donors.

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Incidence and management of atrioventricular conduction disorders in new-onset left bundle branch block after TAVI: A prospective multicenter study.

Heart Rhythm

May 2023

Cardiology Department, CHU Clermont-Ferrand, Clermont-Ferrand, France; Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, SIGMA Clermont, Institut Pascal, Clermont-Ferrand, France. Electronic address:

Background: New-onset left bundle branch block (LBBB) is one of the most frequent complications after transcatheter aortic valve implantation (TAVI) and is associated with delayed high degree atrioventricular (AV) block.

Objectives: The objectives of this study were to determine the incidence of AV block in such a population and to assess the performance and safety of a risk stratification algorithm on the basis of electrophysiology study (EPS) followed by implantation of a pacemaker or implantable loop recorder (ILR).

Methods: This was a prospective open-label study with 12-month follow-up.

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Background: The accurate characterization of grapevine cultivars (Vitis vinifera) is crucial for grape growers, winemakers, wine sellers, consumers and authorities, considering that mistakes could involve significant damage to the wine economic system. To avoid any misunderstanding, morphological, molecular and chemical tools are developed to positively identify grape varieties.

Results: E-ε-viniferin is a stilbene dimer mainly present in the woody part of grapevine and present as a mixture of two enantiomers: (7aR, 8aR)-(-)-E-ε-viniferin (1) and (7aS, 8aS)-(+)-E-ε-viniferin (2).

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Advanced visual computing solutions and three-dimensional (3D) printing are moving from engineering to clinical pipelines for training, planning, and guidance of complex interventions. 3D imaging and rendering, virtual reality (VR), and simulations, as well as 3D printing technologies provide complementary information to better understand the structure and function of the organs, thereby improving and personalizing clinical decisions. In this study, we evaluated several advanced visual computing solutions, such as web-based 3D imaging visualization, VR, and computational fluid simulations, together with 3D printing, for the planning of the left atrial appendage occluder (LAAO) device implantations.

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Electrocardiographic findings in patients with arrhythmogenic cardiomyopathy and right bundle branch block ventricular tachycardia.

Europace

March 2023

Heart Institute, Hadassah University Hospital, Jerusalem and Sackler School of Medicine, Tel-Aviv University, Kyriat Hadassah, PO Box 12000, 91120, Jerusalem, Israel.

Article Synopsis
  • The study investigates patients with right bundle branch block (RBBB)-ventricular tachycardia (VT) and arrhythmogenic cardiomyopathy (ACM) by examining ECG characteristics of sinus rhythm (SR) and VT.
  • It included 70 patients, revealing that the most common sites of origin for the VTs were primarily in the inferior and lateral walls of the left ventricle (LV), with a good correlation to electro-anatomic mapping (EAM) data.
  • The findings highlight frequent abnormalities in SR depolarization and repolarization, which are associated with clinical implications in patients with ACM and RBBB-VT.
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Using a population-based Kalman estimator to model the COVID-19 epidemic in France: estimating associations between disease transmission and non-pharmaceutical interventions.

Int J Biostat

May 2024

Inria, Inria Saclay-Ile de France, France and LMS, CNRS UMR 7649, Ecole Polytechnique, Institut Polytechnique de Paris, Palaiseau, France.

In response to the COVID-19 pandemic caused by SARS-CoV-2, governments have adopted a wide range of non-pharmaceutical interventions (NPI). These include stringent measures such as strict lockdowns, closing schools, bars and restaurants, curfews, and barrier gestures such as mask-wearing and social distancing. Deciphering the effectiveness of each NPI is critical to responding to future waves and outbreaks.

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Early North African Acheulean techno-economic systems at Thomas Quarry I - L1 (Casablanca, Morocco).

J Anthropol Sci

October 2023

Université Paul Valéry Montpellier 3, CNRS, UMR 5140 Archéologie des Sociétés Méditerranéennes, Campus Saint Charles, 34199 Montpellier, France; LabEx Archimède, Université Paul Valéry Montpellier 3, Campus Saint Charles, 34199 Montpellier, France.

North Africa is a key area for understanding cultural processes that led to the Acheulean pan - African emergence and expressions and the related hominin population dynamics. Unfortunately, little is known about the early Acheulean in this vast area of the African continent due to the scarceness of archaeological sites in stratigraphic context with reliable chronometric data, human remains, and technological analyses of the lithic industries. Here, we present the first comprehensive techno-economic analysis of the early Acheulean assemblage from Thomas Quarry I - Unit L1 (ThI-L1, Casablanca, Morocco), which is the earliest Acheulean site of North Africa, unambiguously dated to 1.

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Trends in use of benzodiazepines and Z-drugs in France from 2012 to 2020.

Therapie

November 2023

Université Bordeaux, Inserm, BPH, team Pharmacoepidemiology, U1219, 33000 Bordeaux, France; CHU de Bordeaux, Clinical Pharmacology Unit, 33000 Bordeaux, France.

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Background: The age of infection plays an important role in assessing an individual's daily level of contagiousness, quantified by the daily reproduction number. Then, we derive an autoregressive moving average model from a daily discrete-time epidemic model based on a difference equation involving the age of infection. Novelty: The article's main idea is to use a part of the spectrum associated with this difference equation to describe the data and the model.

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In the energy storage field, an electrode material must possess both good ionic and electronic conductivities to perform well, especially when high power is needed. In this context, the development of composite electrode materials combining an electrochemically active and good ionic conductor phase with an electronic conductor appears as a perfectly adapted approach to generate a synergetic effect and optimize the energy storage performance. In this work, three layered MnO phases with various morphologies (veils, nanoplatelets and microplatelets) were combined with electronic conductor cobalt oxyhydroxides with different platelet sizes (∼20 nm 70 nm wide), to synthesize 6 different composites by exfoliation and restacking processes.

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Polarization singularities and topological polarization structures are generic features of inhomogeneous vector wave fields of any nature. However, their experimental studies mostly remain restricted to optical waves. Here, we report the observation of polarization singularities, topological Möbius-strip structures, and skyrmionic textures in 3D polarization fields of inhomogeneous sound waves.

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Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.

Nat Genet

December 2022

Université Lille, INSERM, Centre Hospitalier Universitaire Lille, Institut Pasteur de Lille, U1167-RID-AGE facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.

Alzheimer's disease (AD), the leading cause of dementia, has an estimated heritability of approximately 70%. The genetic component of AD has been mainly assessed using genome-wide association studies, which do not capture the risk contributed by rare variants. Here, we compared the gene-based burden of rare damaging variants in exome sequencing data from 32,558 individuals-16,036 AD cases and 16,522 controls.

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Background: Here, we aimed to assess the specific features of lung cancer in patients with long-term oxygen therapy (LTOT), and compare their outcomes with patients suffering from lung cancer without LTOT.

Methods: This retrospective, case-controlled study included patients with LTOT and an incident diagnosis of lung cancer treated at Rouen University Hospital.

Results: Out of 2201 patients with LTOT, 31 were diagnosed with lung cancer.

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Enzymatic fingerprinting reveals specific xyloglucan and pectin signatures in the cell wall purified with primary plasmodesmata.

Front Plant Sci

October 2022

Institut Jean-Pierre Bourgin (IJPB), Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'alimentation et l'Environnement (INRAE), AgroParisTech, Versailles, France.

Plasmodesmata (PD) pores connect neighbouring plant cells and enable direct transport across the cell wall. Understanding the molecular composition of these structures is essential to address their formation and later dynamic regulation. Here we provide a biochemical characterisation of the cell wall co-purified with primary PD of cell cultures.

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Robust and accurate acceleration tracking remains a challenge in many fields. For geophysics and economic geology, precise gravity mapping requires onboard sensors combined with accurate positioning and navigation systems. Cold atom-based quantum inertial sensors can potentially provide these high-precision instruments.

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The synergy between drought-responsive traits across different organs is crucial in the whole-plant mechanism influencing drought resilience. These organ interactions, however, are poorly understood, limiting our understanding of drought response strategies at the whole-plant level. Therefore, we need more integrative studies, especially on herbaceous species that represent many important food crops but remain underexplored in their drought response.

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Cold-atom sources for the Matter-wave laser Interferometric Gravitation Antenna (MIGA).

Sci Rep

November 2022

LNE-SYRTE, Observatoire de Paris, Université PSL, CNRS:UMR 8630, Sorbonne Université, 61 avenue de l'Observatoire, 75014, Paris, France.

The Matter-wave laser Interferometric Gravitation Antenna (MIGA) is an underground instrument using cold-atom interferometry to perform precision measurements of gravity gradients and strains. Following its installation at the low noise underground laboratory LSBB in the South-East of France, it will serve as a prototype for gravitational wave detectors with a horizontal baseline of 150 meters. Three spatially separated cold-atom interferometers will be driven by two common counter-propagating lasers to perform a measurement of the gravity gradient along this baseline.

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Xylem hydraulic failure (HF) has been identified as a ubiquitous factor in triggering drought-induced tree mortality through the damage induced by the progressive dehydration of plant living cells. However, fundamental evidence of the mechanistic link connecting xylem HF to cell death has not been identified yet. The main aim of this study was to evaluate, at the leaf level, the relationship between loss of hydraulic function due to cavitation and cell death under drought conditions and discern how this relationship varied across species with contrasting resistances to cavitation.

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Disentangling drivers of litter decomposition in a multi-continent network of tree diversity experiments.

Sci Total Environ

January 2023

Division of Forest, Nature and Landscape, KU Leuven, Celestijnenlaan 200E - box 2411, 3001 Leuven, Belgium. Electronic address:

Article Synopsis
  • Litter decomposition is an important ecological process in forests, influenced by climate, soil, and local characteristics, making it difficult to assess the specific impacts of these factors.
  • A study using data from 15 tree diversity experiments across multiple countries found that tree species identity and plantation conditions significantly impact the rate of litter decomposition, particularly for low-quality litter.
  • After one year, while temperature mainly affected high-quality litter decomposition, the decomposition of low-quality litter was more related to overstory composition and the age of the tree plantations.
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Removal efficiency and adsorption mechanisms of CeO nanoparticles onto granular activated carbon used in drinking water treatment plants.

Sci Total Environ

January 2023

Group of Environmental Physical Chemistry, Department F.-A. Forel for environmental and aquatic sciences, University of Geneva, Uni Carl Vogt, 66, boulevard Carl-Vogt, CH-1211 Geneva 4, Switzerland. Electronic address:

The presence of NPs in drinking water resources raises a global concern on their potential risk for human health, and whether or not drinking water treatment plants are able to effectively remove NPs to prevent their ingestion by humans. In this study, we investigate the efficiency of granular activated carbon (GAC), commonly used in conventional municipal water treatment processes, for the removal of CeO NPs. In ultrapure water, NPs are found to have a good affinity for GAC and results indicate an increase in the adsorption capacity from 0.

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Integrin-based adhesion compartmentalizes ALK3 of the BMPRII to control cell adhesion and migration.

J Cell Biol

December 2022

Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de La Recherche Scientifique 5309, Université Grenoble Alpes, Grenoble, France.

The spatial organization of cell-surface receptors is fundamental for the coordination of biological responses to physical and biochemical cues of the extracellular matrix. How serine/threonine kinase receptors, ALK3-BMPRII, cooperate with integrins upon BMP2 to drive cell migration is unknown. Whether the dynamics between integrins and BMP receptors intertwine in space and time to guide adhesive processes is yet to be elucidated.

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We present a thorough pure rotational investigation of the CHCN radical in its ground vibrational state. Our measurements cover the millimeter and sub-millimeter wave spectral regions (79-860 GHz) using a W-band chirped-pulse instrument and a frequency multiplication chain-based spectrometer. The radical was produced in a flow cell at room temperature by H abstraction from acetonitrile using atomic fluorine.

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Location-weighted versus Volume-weighted Mismatch at MRI for Response to Mechanical Thrombectomy in Acute Stroke.

Radiology

February 2023

From the Institut de Bio-Imagerie IBIO (H.F., T.Y., V.D., T.T.), CNRS, UMR-5287 (I.S., S.S.), and INSERM, Neurocentre Magendie, U1215 (V.D., T.T.), Université Bordeaux, 146 rue Léo Saignat, F-33000 Bordeaux Cedex, France; Unité Neurovasculaire (I.S., S.O., S.S., P.R., M.P., S.D.) and Neuroimagerie Diagnostique et Thérapeutique (G.M., V.D., T.T.), CHU de Bordeaux, Bordeaux, France; Stanford Stroke Center, Stanford University, Stanford, Calif (S.C., G.W.A.); Unité Neurovasculaire (N.R., J.F.A., L.C., A.V., J.M.O.), Service de Neuroradiologie (A.G., J.D., F.B., C.C.), and Centre d'Investigation Clinique (A.D., C.T., A.S., V.R.), CHU de Toulouse, Toulouse, France; and Fondation Ophtalmologique Adolphe de Rothschild, Paris, France (M.M.).

Background A target mismatch profile can identify good clinical response to recanalization after acute ischemic stroke, but does not consider region specificities. Purpose To test whether location-weighted infarction core and mismatch, determined from diffusion and perfusion MRI performed in patients with acute stroke, could improve prediction of good clinical response to mechanical thrombectomy compared with a target mismatch profile. Materials and Methods In this secondary analysis, two prospectively collected independent stroke data sets (2012-2015 and 2017-2019) were analyzed.

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