116 results match your criteria: "Universitatii Str[Affiliation]"
Medicina (Kaunas)
January 2025
Department of Surgery, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
: Up until now, behavioral interventions and pharmacological therapies were the main approach available for the management of obesity. Diet and exercise, when used as a singular therapeutic method, are inadequate for a successful outcome. Research shows promising results for the surgical treatment of obesity, especially in the area of bariatric surgery (BaS).
View Article and Find Full Text PDFBioorg Med Chem
January 2025
Alexandru Ioan Cuza University of Iasi, Faculty of Chemistry, Bd. Carol 11, 700506 Iasi, Romania. Electronic address:
In the last decades fungal infections became a major threat to human health having an unacceptably occurrence, a high rate of mortality and the number of patients at risk for these infections continue to increase every year. An effective, modern and very useful strategy in antifungal therapy is represented by the use of chimeric and hybrid drugs, most of them being with azaheterocycle skeleton. In this review, we present an overview from the last five years of the most representative achievements in the field of chimeric and hybrid diazine derivatives with antifungal properties.
View Article and Find Full Text PDFPhys Med
January 2025
Dept of Systems and Computer Engineering, Carleton University, Ottawa, ON K1S 5B6, Canada.
Background: Working from home during the Covid-19 pandemic was perceived differently by men and women working in STEM fields. The aim of this paper is to highlight the unexpected benefits generated by working from home during the pandemic.
Methods: Qualitative methodology was used to analyze data, collected via survey.
Diagnostics (Basel)
November 2024
Faculty of Dental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 Universitatii Str., 700115 Iasi, Romania.
Background: This study aimed to compare the accuracy of linear measurements obtained using the classical (manual) method versus cone-beam computed tomography (CBCT) in craniofacial anthropometry, specifically targeting the infraorbital foramen (IOF).
Methods: This study involved two sample groups: one of 40 dry skulls measured manually using digital calipers, and the other of 40 CBCT 3D images digitally measured. Measurements included IOF height, distances between the IOF and nasion (N), IOF and frontomalar orbital (FMO), and between the two IOFs.
Int J Biol Macromol
November 2024
Center for Low-temperature Plasma Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
Plasma-activated chitosan (PAC) colloids for cancer treatment were obtained by using the cold atmospheric plasma technique. Chitosan solutions were irradiated by plasma ignited in argon gas and in a mixture of argon with nitrogen and oxygen gases in certain ratios. The structural modifications of chitosan and the chemical species generated in plasma were investigated by EPR, LC-MS/MS, XRD, DLS, and TGA methods.
View Article and Find Full Text PDFDiagnostics (Basel)
September 2024
Faculty of Dental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 Universitatii Str., 700115 Iasi, Romania.
Medicina (Kaunas)
August 2024
Faculty of Dental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy Iasi, 16 Universitatii Str., 700115 Iasi, Romania.
: Facial symmetry is a key component of facial beauty and attractiveness. However, perfect symmetry is rare, and slight asymmetries, also known as natural asymmetries, are common and contribute to the uniqueness of each face. The perception of facial asymmetry varies among individuals and can be influenced by several factors.
View Article and Find Full Text PDFAnimals (Basel)
August 2024
Division of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Nowoursynowska Str. 159c, 02-776 Warsaw, Poland.
The widespread and uncontrolled use of anthelmintic products has contributed to the emergence of anthelmintic resistance (AR). This phenomenon globally threatens the productivity and welfare of small ruminants. A questionnaire consisting of 34 questions was handed to 234 goat farmers across Romania to gain insight into control practices against internal parasites and the farmers' perception of the parasitic infections present in their herds and the efficacy of anthelmintic treatments.
View Article and Find Full Text PDFCurr Issues Mol Biol
July 2024
Faculty of Medicine and Faculty of Dentistry, "Vasile Goldis" Western University of Arad, Liviu Rebreanu Str., No. 86, 310045 Arad, Romania.
Chlorogenic acids are plant secondary metabolites, chemically-polyphenols with similar biological activity, formed through the esterification of quinic acid and hydrocinnamic acid moieties. They are best known for their high concentration in coffee and other dietary sources and the antioxidant properties that they exhibit. Both chlorogenic acids and plant extracts containing significant amounts of the compounds show promising in vitro activity against colorectal cancer.
View Article and Find Full Text PDFFuture Med Chem
June 2024
Alexandru Ioan Cuza University of Iasi, Faculty of Chemistry, 11 Carol 1st Bvd, Iasi 700506, Romania.
During the last decades, five or six member rings azaheterocycles compounds appear to be an extremely valuable source of antifungal agents. Their use seems to be a very attractive solution in antifungal therapy and to overcome antifungal resistance in agriculture. The present review highlights the main results obtained in the field of hybrid and chimeric azine (especially pyridine, quinoline, phenanthroline, bypyridine, naphthyridine and their fused derivatives) derivatives presented in scientific literature from the last 10 years, with emphasis on antifungal activity of the mentioned compounds.
View Article and Find Full Text PDFDent J (Basel)
April 2024
Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, "Gr. T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.
Unlabelled: Orthodontic mini-implants are devices used for anchorage in various orthodontic treatments. We conducted a pilot study which aimed to observe preliminary trends regarding the impact of heat treatment on the elastic modulus of Ti6Al4V alloy and stainless steel 316L mini-implants. The initial phase involved testing the impact of heat treatment on the mechanical properties of Ti6Al4V alloy and stainless steel 316L mini-implants.
View Article and Find Full Text PDFDent J (Basel)
April 2024
Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.
Introduction: The aim of this in vitro study was to compare the quality of marginal sealing at the cervical margins of indirect and direct composite resin restorations in mesio-occluso-distal (MOD) cavities.
Material And Method: MOD preparations were performed on 30 extracted teeth. The mesial cervical margin of each tooth was relocated using a flow composite resin (Enamel Plus HRi Flow, Micerium, Avegno, GE, Italy), then the samples were divided into three groups.
Materials (Basel)
December 2023
Department of Chemistry, Faculty of Informatics and Sciences, University of Oradea, 1 Universitatii Str., 410087 Oradea, Romania.
Nowadays, choosing a corrosion inhibitor is not only based on efficiency, but must also consider the toxicity of the compound, the impact on the environment, and, obviously, the regulations in the field. In the last two decades, a special class of substances has begun to be studied, namely polyoxometalates (POMs). Their electronic properties and redox characteristics make the polyoxometalates potential candidates to be used in many electrochemical processes, and as potential corrosion inhibitors.
View Article and Find Full Text PDFMedicina (Kaunas)
November 2023
Faculty of Medicine, "Titu Maiorescu" University of Medicine, 67A Gheorghe Petrascu Str., 031593 Bucharest, Romania.
: Health professionals have voiced concerns about the danger of self-medication in times of growing use of over-the-counter medicines and, in some contexts, the unregulated selling of them. Previous research has examined the incidence of parental self-medication as well as the use and abuse of antibiotics without medical advice. However, these studies have limited evidence on the role of family doctors and the perceived severity of self-medication in the case of parents.
View Article and Find Full Text PDFJ Clin Med
December 2023
Department of Medical Specialties II, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
(1) Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease of autoimmune etiology. Increased scientific evidence suggests that immune-mediated inflammatory dis-eases are associated with autonomic nervous system (ANS) dysfunction. Studies proved that autonomic imbalance is correlated with RA evolution and may explain augmented cardiovascular pathology and mortality not attributable to classical risk factors.
View Article and Find Full Text PDFJ Clin Med
December 2023
Department of Medical Specialties I, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
(1) Background: Telerehabilitation is an approach that uses digital technology to provide remote medical recovery services. It can be an option for cardiovascular recovery at home in patients with peripheral arterial disease (PAD) of the lower limbs. (2) Methods: We performed literature research through two databases: PubMed and Embase.
View Article and Find Full Text PDFChildren (Basel)
October 2023
Faculty of Medicine, "Titu Maiorescu" University of Medicine, 67A Gheorghe Petrascu Str., 031592 Bucharest, Romania.
Background: antibiotic resistance has increased worldwide and affects the effectiveness of current therapies. The recommended first-line empiric treatment should be tailored to the local clarithromycin resistance rate. This study aimed to determine the pediatric patient profile and rate of clarithromycin resistance for patients diagnosed with by gastric biopsy.
View Article and Find Full Text PDFBioengineering (Basel)
November 2023
Department of Electrical Measurements and Materials, Faculty of Electrical Engineering and Information Technology, Gheorghe Asachi Technical University of Iasi, 700050 Iasi, Romania.
Background: Alzheimer's disease (AD), along with other neurodegenerative disorders, remains a challenge for clinicians, mainly because of the incomplete knowledge surrounding its etiology and inefficient therapeutic options. Considering the central role of amyloid beta (Aβ) in the onset and evolution of AD, Aβ-targeted therapies are among the most promising research directions. In the context of decreased Aβ elimination from the central nervous system in the AD patient, the authors propose a novel therapeutic approach based on the "Cerebrospinal Fluid Sink Therapeutic Strategy" presented in previous works.
View Article and Find Full Text PDFJ Funct Biomater
November 2023
Faculty of Dental Medicine, "Apollonia" University of Iasi, 11 Pacurari Str., 700511 Iasi, Romania.
Nowadays, infection diseases are one of the most significant threats to humans all around the world. An encouraging strategy for solving this issue and fighting resistant microorganisms is to develop drug carriers for a prolonged release of the antibiotic to the target site. The purpose of this work was to obtain metronidazole-encapsulated chitosan nanoparticles using an ion gelation route and to evaluate their properties.
View Article and Find Full Text PDFBiomedicines
September 2023
Faculty of Dental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iași, Romania.
There are two main methods used for dentin hypersensitivity (DH) treatment: dentinal tubule occlusion and blockage of nerve activity. Dentifrices are the most common vehicles for active ingredients used for DH treatment. The aim of this study was to evaluate the efficacy of three toothpastes on dentinal tubule occlusion, mineral acquisition, and dentin hardness.
View Article and Find Full Text PDFMedicina (Kaunas)
August 2023
ENT, 2nd Surgery Department, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.
J Funct Biomater
July 2023
Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.
The aim of the study was to evaluate the antibacterial activity and surface hardness of a light-activated microhybrid composite resin modified with green silver nanoparticles (AgNPs). AgNPs were synthesized using an extract and characterized through different methods such as UV-Vis, EDX, and FTIR. The obtained AgNPs were mixed with a microhybrid composite resin (Herculite XRV, Kerr Corp.
View Article and Find Full Text PDFPolymers (Basel)
August 2023
Textile Research Group, Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam 40450, Selangor, Malaysia.
Nanofibres have gained attention for their highly porous structure, narrow pore size, and high specific surface area. One of the most efficient techniques for producing nanofibres is electrospinning. These fibres are used in various fields, including water filtration.
View Article and Find Full Text PDFLife (Basel)
July 2023
Doctoral School, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.
Artificial intelligence (AI) is rapidly integrating into diagnostic methods across many branches of medicine. Significant progress has been made in tumor assessment using AI algorithms, and research is underway on how image manipulation can provide information with diagnostic, prognostic and treatment impacts. Glioblastoma (GB) remains the most common primary malignant brain tumor, with a median survival of 15 months.
View Article and Find Full Text PDFHealthcare (Basel)
July 2023
Arheoinvest Center, Department of Natural and Exact Sciences, Institute of Interdisciplinary Research, Alexandru Ioan Cuza University of Iasi, 22 Carol I Blvd., 700505 Iasi, Romania.
The paper presents the evolution of the concentration level for four particle size groups of microaerosols (1.0, 2.5, 4.
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