1 results match your criteria: "Universitat Pompeu Fabra and BRN[Affiliation]"
COPD: systemic proteomic profiles in frequent and infrequent exacerbators.
ERJ Open Res
March 2024
Servei de Pneumologia, Hospital del Mar - IMIM, MELIS Dept, Universitat Pompeu Fabra and BRN, Barcelona, Spain.
Article Synopsis
- The study aimed to compare the systemic proteomic profiles of frequent exacerbators (FE) and non-frequent exacerbators (NFE) among COPD patients, alongside a reference group of healthy controls (HC) and patients during an exacerbation (AE).
- Analysis included 40 stable COPD patients (20 FE and 20 NFE), and results showed 40 different proteins in FE, 10 in NFE, and 63 in AE compared to HC.
- Results indicated that FE patients had specific inflammatory dysregulations, with some proteomic changes shared with AE, while others were unique to exacerbation episodes.