The performance of field sampling for parasite detection in a wild passerine.

Parasites can impact the behavior of animals and alter the interplay with ecological factors in their environment. Studying the effects that parasites have on animals thus requires accurate estimates of infections in individuals. However, quantifying parasites can be challenging due to several factors.

Critical analysis on the reproducibility of visual quality assessment using deep features.

Data used to train supervised machine learning models are commonly split into independent training, validation, and test sets. This paper illustrates that complex data leakage cases have occurred in the no-reference image and video quality assessment literature. Recently, papers in several journals reported performance results well above the best in the field.

Force Generation in Confined Active Fluids: The Role of Microstructure.

We experimentally determine the force exerted by a bath of active particles onto a passive probe as a function of its distance to a wall and compare it to the measured averaged density distribution of active particles around the probe. Within the framework of an active stress, we demonstrate that both quantities are-up to a factor-directly related to each other. Our results are in excellent agreement with a minimal numerical model and confirm a general and system-independent relationship between the microstructure of active particles and transmitted forces.

[Patient Factors in Offender Treatment: Personality, Therapy Motivation and Outcome].

Using a systematic literature review according to the PRISMA criteria, patient factors of offenders were related to forensic outcomes. Searches were conducted in the PsycInfo and PSYNDEX databases; further relevant studies were taken from the bibliographies of studies that met the selection criteria. Only quantitative empirical studies for the period 1990-2021 were included.

Understanding enhanced rotational dynamics of active probes in rod suspensions.

Active Brownian particles (APs) have recently been shown to exhibit enhanced rotational diffusion (ERD) in complex fluids. Here, we experimentally observe ERD and numerically corroborate its microscopic origin for a quasi-two-dimensional suspension of colloidal rods. At high density, the rods form small rafts, wherein they perform small-amplitude, high-frequency longitudinal displacements.

Reversible Multielectron Release from Redox-Active Three-Dimensional Molecular Barrels with Ruthenium-Alkenyl Moieties.

Three-dimensional molecular barrels and were synthesized in high yields from dinuclear ruthenium-vinyl clamps and tritopic triphenylamine-derived carboxylate linkers and characterized by multinuclear NMR spectroscopy including H-H COSY and H DOSY measurements, high-resolution electrospray ionization mass spectrometry, and X-ray crystallography. The metal frameworks of the cages adopt the shape of twisted trigonal prisms, and they crystallize as racemic mixtures of interdigitating Δ- and Λ-enantiomers with a tight columnar packing in . Electrochemical studies and redox titrations revealed that the cages are able to release up to 11 electrons on the voltammetric timescale and that their cage structures persist up to the hexacation level.

Exploring Structure-Property Relations of B,S-Doped Polycyclic Aromatic Hydrocarbons through the Trinity of Synthesis, Spectroscopy, and Theory.

Polycyclic aromatic hydrocarbons (PAHs) are prominent lead structures for organic optoelectronic materials. This work describes the synthesis of three B,S-doped PAHs with heptacene-type scaffolds via nucleophilic aromatic substitution reactions between fluorinated arylborane precursors and 1,2-(MeSiS)CH/1,8-diazabicyclo[5.4.

Phagocytosis mediated by the human granulocyte receptor CEACAM3 is limited by the receptor-type protein tyrosine phosphatase PTPRJ.

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) is a human granulocyte receptor mediating the efficient phagocytosis of a subset of human-restricted bacterial pathogens. Its function depends on phosphorylation of a tyrosine-based sequence motif, but the enzyme(s) responsible for reversing this modification are unclear. Here, we identify the receptor-type protein tyrosine phosphatase PTPRJ as a negative regulator of CEACAM3-mediated phagocytosis.

The heritability of vocal tract structures estimated from structural MRI in a large cohort of Dutch twins.

While language is expressed in multiple modalities, including sign, writing, or whistles, speech is arguably the most common. The human vocal tract is capable of producing the bewildering diversity of the 7000 or so currently spoken languages, but relatively little is known about its genetic bases, especially in what concerns normal variation. Here, we capitalize on five cohorts totaling 632 Dutch twins with structural magnetic resonance imaging (MRI) data.

Green hydrothermal synthesis yields perylenebisimide-SiO hybrid materials with solution-like fluorescence and photoredox activity.

In organic-inorganic hybrid materials' (HMs) synthesis, it is intrinsically challenging to, at the same time, achieve (i) the concomitant synthesis of the components, (ii) nanoscopic interpenetration of the components, and (iii) covalent linking of the components. We here report the one-pot hydrothermal synthesis (HTS) of inorganic-organic HMs consisting of perylene bisimide (PBI) dyes and silica, using nothing but water as the medium and directly from the corresponding bisanhydrides, -alkyl amines, and alkoxysilane precursors. First, in the absence of a functionalized alkoxysilane for linking, a mixture of the products, PBI and SiO, is obtained.

Role of cohesion in the flow of active particles through bottlenecks.

We experimentally and numerically study the flow of programmable active particles (APs) with tunable cohesion strength through geometric constrictions. Similar to purely repulsive granular systems, we observe an exponential distribution of burst sizes and power-law-distributed clogging durations. Upon increasing cohesion between APs, we find a rather abrupt transition from an arch-dominated clogging regime to a cohesion-dominated regime where droplets form at the aperture of the bottleneck.

Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy.

Cisplatin induces DNA crosslinks that are highly cytotoxic. Hence, platinum complexes are frequently used in the treatment of a broad range of cancers. Efficiency of cisplatin treatment is limited by the tumor-specific DNA damage response to the generated lesions.

Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.

Background: Risk-adjusted cancer screening and prevention is a promising and continuously emerging option for improving cancer prevention. It is driven by increasing knowledge of risk factors and the ability to determine them for individual risk prediction. However, there is a knowledge gap between evidence of increased risk and evidence of the effectiveness and efficiency of clinical preventive interventions based on increased risk.

Mitochondrial phosphoenolpyruvate carboxylase contributes to carbon fixation in the diatom Phaeodactylum tricornutum at low inorganic carbon concentrations.

Photosynthetic carbon fixation is often limited by CO availability, which led to the evolution of CO concentrating mechanisms (CCMs). Some diatoms possess CCMs that employ biochemical fixation of bicarbonate, similar to C plants, but whether biochemical CCMs are commonly found in diatoms is a subject of debate. In the diatom Phaeodactylum tricornutum, phosphoenolpyruvate carboxylase (PEPC) is present in two isoforms, PEPC1 in the plastids and PEPC2 in the mitochondria.

The Thermodynamic Stability of Membrane Proteins in Micelles and Lipid Bilayers Investigated with the Ferrichrom Receptor FhuA.

Extraction of integral membrane proteins into detergents for structural and functional studies often leads to a strong loss in protein stability. The impact of the lipid bilayer on the thermodynamic stability of an integral membrane protein in comparison to its solubilized form in detergent was examined and compared for FhuA from Escherichia coli and for a mutant, FhuAΔ5-160, lacking the N-terminal cork domain. Urea-induced unfolding was monitored by fluorescence spectroscopy to determine the effective free energies [Formula: see text] of unfolding.

Bowl-Shaped Symmetric and Non-symmetric Bis-functionalized Indacenopicenes.

Regioselective arrangement of two groups of orthogonal reactivity in bowl-shaped -indaceno[3,2,1,8,7,6-]picene (Idpc) was key for the synthesis of hetero-bis-functionalized Idpc derivatives. Halogen and methyl groups were positioned at specific positions in the rim area of Idpc at an early stage during the synthesis by functionalization of suitable precursors. Regioselective functionalization of the bowl's rim was then finally achieved either via consecutive Cu(I)-catalyzed azide-alkyne coupling (CuAAC) and C-C cross-coupling reactions or by C-C cross-coupling alone, giving access to either symmetric or non-symmetric bis-functionalized Idpc derivatives.

Influence of anisotropy on heterogeneous nucleation of gold nanorod assemblies.

In this study, we analysed for the first time heterogeneous nucleation with anisotropic nanoparticles as a model system for non-spherical building units on the nanoscale. Gold nanorods were synthesised and assembled to investigate the phenomenon of heterogeneous nucleation. To determine the influence of the particle shape on heterogeneous nucleation, we utilised gold nanorods with varying aspect ratios, ranging from 3.

Crystal structure of SFPQ-NONO heterodimer.

The Drosophila behavior/human splicing (DBHS) protein family is composed of the three members SFPQ, NONO and PSPC1. These proteins share a strong sequence and structural homology within the core-structured domains forming obligate homo- and heterodimers. This feature may lead to the simultaneous existence of six different dimeric complexes that sustain their function in many cellular processes such as pre-mRNA splicing, innate immunity, transcriptional regulation.

Electron-Rich Diruthenium Complexes with π-Extended Alkenyl Ligands and Their F TCNQ Charge-Transfer Salts.

The synthesis of dinuclear ruthenium alkenyl complexes with {Ru(CO)(P Pr ) (L)} entities (L=Cl in complexes Ru -3 and Ru -7; L=acetylacetonate (acac ) in complexes Ru -4 and Ru -8) and with π-conjugated 2,7-divinylphenanthrenediyl (Ru -3, Ru -4) or 5,8-divinylquinoxalinediyl (Ru -7, Ru -8) as bridging ligands are reported. The bridging ligands are laterally π-extended by anellating a pyrene (Ru -7, Ru -8) or a 6,7-benzoquinoxaline (Ru -3, Ru -4) π-perimeter. This was done with the hope that the open π-faces of the electron-rich complexes will foster association with planar electron acceptors via π-stacking.

Elasticity in crystals with a high density of local defects: Insights from ultra-soft colloids.

In complex crystals close to melting or at finite temperatures, different types of defects are ubiquitous and their role becomes relevant in the mechanical response of these solids. Conventional elasticity theory fails to provide a microscopic basis to include and account for the motion of point defects in an otherwise ordered crystalline structure. We study the elastic properties of a point-defect rich crystal within a first principles theoretical framework derived from the microscopic equations of motion.

Intermodality differences in statistical learning: phylogenetic and ontogenetic influences.

In Basque-Spanish bilinguals, statistical learning (SL) in the visual modality was more efficient on nonlinguistic than linguistic input; in the auditory modality, we found the reverse pattern of results. We hypothesize that SL was shaped for processing nonlinguistic environmental stimuli and only later, as the language faculty emerged, recycled for speech processing. This led to further adaptive changes in the neurocognitive mechanisms underlying speech processing, including SL.

Polarized phonons carry angular momentum in ultrafast demagnetization.

Magnetic phenomena are ubiquitous in nature and indispensable for modern science and technology, but it is notoriously difficult to change the magnetic order of a material in a rapid way. However, if a thin nickel film is subjected to ultrashort laser pulses, it loses its magnetic order almost completely within femtosecond timescales. This phenomenon is widespread and offers opportunities for rapid information processing or ultrafast spintronics at frequencies approaching those of light.

Barrier Crossing in a Viscoelastic Bath.

We investigate the hopping dynamics of a colloidal particle across a potential barrier and within a viscoelastic, i.e., non-Markovian, bath and report two clearly separated timescales in the corresponding waiting time distributions.