Chili cultivars vulnerability: a multi-factorial examination of disease and pest-induced yield decline across different growing microclimates and watering regimens.

Background: As identified by the research, it is imperative to develop effective ways to address the pressing problem of disease and pest susceptibility in chili agriculture and secure sustainable crop yield. The research examines the impact of various growing microclimates, watering regimens, and chili cultivars on disease incidence, pest attacks, and yield loss.

Results: The study, which took place over a season, used a randomized complete block design to evaluate how well Tanjung, Unpad, and Osaka cultivars performed in four different watering regimens (100, 75, 50, and 25% ETc) and different microclimates (greenhouse, rain shelter, screen house, and open field).

Assessing the climate adaptive potential of imported Chili in comparison with local cultivars through germination performance analysis.

Background: The study offers insightful information about the adaptability of local and imported Chili cultivars. This experiment examines how three different chili cultivars Tanjung, Unpad, and Osaka perform in the germination and early growth phases while considering a wide range of environmental conditions. Research conducted in Jatinangor, Sumedang Regency, Indonesia, highlights the differences between cultivars and the varied possibilities for adaptability each variation possesses.

Computational Study of Bis-(1-(Benzoyl)-3-Methyl Thiourea) Platinum (II) Complex Derivatives as Anticancer Candidates.

Background: The increasing incidence of cancer every year has resulted in cancer becoming one of the most common causes of death in the world. The most common types of cancer are breast cancer, lung cancer and prostate cancer. Thiourea is one of the compounds that have anticancer effects, and its activity can be increased by structural modifications, one of which involves making a Bis-(1-(benzoyl)-3-methyl thiourea) platinum (II) metal complex.

Corrigendum to "Design, molecular docking, and molecular dynamics of thiourea-iron (III) metal complexes as NUDT5 inhibitors for breast cancer treatment" [Heliyon 8 (9) (2022) e10694].

[This corrects the article DOI: 10.1016/j.heliyon.

Design, molecular docking, and molecular dynamics of thiourea-iron (III) metal complexes as NUDT5 inhibitors for breast cancer treatment.

In research, anticancer agents, such as thiourea derivative compounds, and metal complexes, such as those complexed with iron (III) metal, are often studied. The metal complexes are presumably more active than thiourea derivatives as free ligands; some negative effects may be reduced. The computational studies used in this study involved molecular docking with AutoDock and molecular dynamics (MD) simulations using Desmond to evaluate the stability of the interactions.

Synthesis, Anticancer Activity, Structure-Activity Relationship, and Molecular Modeling Studies of α-Mangostin Derivatives as hERα Inhibitor.

α-Mangostin is one of the secondary metabolites in mangosteen pericarp, which has been reported to have anti-breast cancer activity. In our previous study, three α-mangostin derivatives were computationally designed as hERα antagonists. In this present study, the designed compounds were synthesized undergoing a benzoylation reaction between α-mangostin with three benzoyl chloride derivatives to produce three derivatives, namely, , , and .

α-Mangostin and its derivatives against estrogen receptor alpha.

Estrogen receptor alpha (ERα) acts as the transcription factor and the main therapeutic target against breast cancer. One of the compounds that has been shown to act as an ERα is α-mangostin. However, it still has weaknesses due to its low solubility and low potent activity.

The effects of mangosteen peel ( L.) and Turmeric ( Val) flour dietary supplementation on the growth performance, lipid profile, and abdominal fat content in Cihateup ducks.

Background: Bioactive compounds in mangosteen peel and turmeric have been shown to possess antioxidant and hypolipidemic properties.

Aim: This study aimed to examine the effect of mangosteen peel flour (MF) and turmeric flour (TF) dietary supplementation on the performance, lipid profile, and abdominal fat content of Cihateup ducks.

Materials And Methods: The study was conducted for 56 days (8 weeks) using 84-day-old male Cihateup ducks that were allocated into seven treatments with three replications and each containing four ducks as subreplicates.