102 results match your criteria: "Universitas Padjadjaran-Dr. Hasan Sadikin Hospital[Affiliation]"

Introduction: Chest X-ray (CXR) remains one of the tools used in diagnosing tuberculosis (TB). However, few studies about such tools exist, specifically in children in Indonesia. We aim to investigate and compare the CXR findings of children with pulmonary drug-resistant TB (DR-TB) and drug-sensitive TB (DS-TB) that could help in the evaluation and management of TB cases in children.

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Background is a complication in patients with transfusion-dependent thalassemia (TDT). There are several mechanisms underlying pain in people with thalassemia and low hemoglobin at the end of the transfusion cycle was the most etiology. Pain can develop into chronic pain and interfere with the quality of life.

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Dermatofibrosarcoma Protuberans in a 12-Year-Old Child: A Rare Case.

Clin Cosmet Investig Dermatol

August 2024

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.

Article Synopsis
  • Dermatofibrosarcoma protuberans (DFSP) is a rare skin tumor that typically appears as a firm, slowly growing plaque, mostly found in the trunk area and is uncommon in children.
  • A 12-year-old girl showed symptoms of DFSP with a painless dark patch on her nose after radiotherapy; she underwent wide local excision resulting in the removal of the tumor.
  • Histopathological examination confirmed the diagnosis as stage II DFSP, and treatment included 25 sessions of radiotherapy, with no recurrence observed after subsequent surgeries.
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Background: One of the downsides of percutaneous coronary intervention (PCI) is stent failure which could be related to stent underexpansion. Hence, PCI based on an accurate coronary artery size obtained from intracoronary imaging is tremendously important. Until now, there is no data about all coronary artery dimensions in the Southeast Asian population performed by intravascular ultrasound (IVUS).

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Clinical characteristics of enteric fever and performance of TUBEX TF IgM test in Indonesian hospitals.

PLoS Negl Trop Dis

July 2024

Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Central Jakarta, Indonesia.

Article Synopsis
  • Accurate diagnosis of enteric fever is difficult in low- and middle-income countries due to overlapping symptoms with other illnesses; this study evaluated the effectiveness of the TUBEX TF test in Indonesia.
  • Out of 301 patients clinically diagnosed with enteric fever, only 16.6% were confirmed through blood culture or PCR, with common symptoms including fever and abdominal pain predominantly in school-aged children.
  • The TUBEX TF test showed mixed results, with high sensitivity but low specificity, leading to over-diagnosis; acute IgG testing proved more reliable for identifying true cases of enteric fever.
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  • Skin aging can be accelerated by UV radiation, leading to reactive oxidative stress and premature aging.
  • This study investigates the anti-aging effects of a secretome gel derived from human Wharton Jelly Mesenchymal Stem Cells (hWJ-MSCs) using a UVB-induced mouse model.
  • Results showed that the secretome gel improved collagen density, reduced inflammation, and altered gene and protein expressions related to aging, suggesting its potential in preventing and treating skin aging.
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Background: The use of three-dimensional (3D) technology helps surgeons in performing autologous microtia reconstruction due to more accurate measurements and a better precision template model. However, the technical aspects of using a 3D imaging and 3D-printed model and the difference in outcomes postoperatively remain poorly reviewed.

Purpose: This systematic review aimed to provide the current evidence of the benefit and technical aspects of using 3D technology in autologous microtia reconstruction.

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  • Leprosy is a chronic infectious disease caused by Mycobacterium leprae, primarily affecting the skin and peripheral nerves, with few studies focusing on its impacts on nails.
  • An observational study in West Java, Indonesia, sought to document nail changes in leprosy patients using dermoscopy, revealing that a significant number of patients experienced various dermoscopic nail abnormalities.
  • The findings indicated that most changes occurred in males and younger patients, with longitudinal ridges being the most common nail feature observed, alongside other conditions like transverse lines and subungual hemorrhage.
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Background: Adenomyosis is a gynaecological condition characterized by the infiltration of endometrial glands and stroma resulting in ectopic intramyometrial, leading to the generalized enlargement of the uterus. Various cyclical regimens are employed globally to assist infertile women with adenomyosis during in-vitro fertilization (IVF) treatment because there is no consensus regarding the best protocol for managing adenomyosis.

Case: The authors reported two cases the administration of long IVF protocol in Adenomyosis with pregnancy outcome.

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Increased survival rate of patients with Transfusion-dependent Thalassemia (TDT) should be in line with their good quality of life (QoL). The study aimed to analyze the relationship between sociodemographic factors and clinical characteristics with the QoL of children with TDT. A cross-sectional study was conducted at Hasan Sadikin General Hospital from December 2022 to February 2023.

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Purpose: This study aimed to determine the survival rates and treatment outcomes of patients with childhood Acute Lymphoblastic Leukemia (ALL) in a single-center study at Indonesia.

Patients And Methods: Factors contributing to the relapse and survival of ALL in Bandung, Indonesia, were evaluated. Data were collected from the medical record and the Indonesian Pediatric Cancer Registry (IPCAR).

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Vulvar intraepithelial neoplasia (VIN), the precursor lesion of vulvar squamous cell carcinoma (VSCC), may present as pruritic or asymptomatic lichenified plaques surrounded by single or multiple discrete or confluent macules or papules. VIN is divided into high-grade squamous intraepithelial lesion (HSIL), which is human papillomavirus (HPV)-driven, and differentiated VIN (DVIN), which develops independently of HPV. Histopathological examination and HPV genotyping polymerase chain reaction (PCR) tests should be performed to distinguish between HSIL and DVIN.

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Article Synopsis
  • Syphilis is a sexually-transmitted disease that can present in different stages, with secondary syphilis symptoms sometimes resembling other skin conditions, especially in patients co-infected with HIV.
  • A 22-year-old man with HIV presented with multiple asymptomatic skin lesions, and laboratory tests confirmed he had secondary syphilis; he was treated with benzathine penicillin G.
  • Following treatment, most of his lesions faded within a month, highlighting the potential for atypical presentations of secondary syphilis to cause diagnostic challenges and delayed care, especially in HIV-positive individuals.
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Anogenital warts (AGWs) are globally recognized as the most common sexually transmitted infections (STIs) caused by the human papillomavirus (HPV), particularly types 6 and 11. Meanwhile, immunotherapy is one of the treatments of choice for patients with extensive AGWs. Measles, mumps, and rubella (MMR) vaccine induce the production of various T helper 1 cytokines to elicit immune responses, resulting in the clearance of both treated and untreated warts.

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Introduction And Importance: Macrostomia is a congenital deformity found in Tessier no. 7 facial clefts defined as an enlargement of the mouth at the oral commissure. Several techniques are described in literature to achieve optimal functional and aesthetic results, with varying results and surgeon preferences.

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Introduction: Indonesia is the most populous Muslim-majority country, where some women wear hijab covering their scalp and neck. Some hijab-wearing women complain of scalp problems eg, itch, dandruff, and hair loss, which might be related to severe and chronic skin barrier impairment due to occlusion. Excessive water accumulation in the occluded stratum corneum might result in increased permeability, followed by increased skin pH values.

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  • Tufted angioma (TA) is a rare, benign vascular tumor that typically appears in infants, characterized by reddish or purplish lesions, and is difficult to treat effectively.
  • A case study of a 15-year-old girl with TA showed improvement in her painful, purplish plaques after applying pulsed dye laser (PDL) treatment over several sessions.
  • PDL specifically targets the abnormal blood vessels in TA, leading to reduced redness and pain with minimal damage to surrounding skin.
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Background: Interleukin 17 (IL-17) and interferon gamma (IFN-γ) play a role in the pathogenesis of psoriasis vulgaris (PV). Topical corticosteroids are still utilised as first-line therapy for mild to moderate PV. However, long-term use of corticosteroid is associated with various side effects.

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Lupus erythematosus profundus (LEP) is a rare subset of chronic cutaneous lupus erythematosus (CCLE), with a reported incidence of 1-3% in all LE cases. The most common cutaneous clinical presentation includes indurated plaques or subcutaneous nodules with an overlying normal skin. The clinical findings range from skin redness to features of CCLE, such as scaling, follicular plugging, and atrophy.

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Purpose: This study aims to delineate the demographic and clinical characteristics of xerosis, pruritus, and pallor among patients with stage 5 chronic kidney disease (CKD) undergoing hemodialysis at Dr. Hasan Sadikin General Hospital, Bandung.

Patients And Methods: This cross-sectional, descriptive study involved the analysis of 139 selected medical records of patients with stage 5 CKD who underwent hemodialysis between July and August 2022.

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Article Synopsis
  • Acne vulgaris (AV) is a common skin condition linked to factors leading to antibiotic resistance, especially due to bacteria forming biofilms, which complicates treatment.
  • This study compared antibiotic resistance between biofilm-forming (BF) and non-biofilm-forming (NBF) bacterial strains associated with AV, examining 60 patients using skin biopsies and various testing methods.
  • Results showed no significant differences in antibiotic resistance rates between BF and NBF groups, though some resistance to clindamycin, erythromycin, and azithromycin was noted, suggesting careful use of these antibiotics in treatment.
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Recurrent Partial Hydatidiform Mole: A Case Report of Seven Consecutive Molar Pregnancies.

Int J Womens Health

August 2023

Division of Pharmacology and Therapy, Department of Anatomy, Histology, and Pharmacology, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.

Hydatidiform mole (HM) is an aberrant pregnancy characterized by atypical trophoblastic hyperplasia, hydropic chorionic villi, and deprived fetal development. There are two types of HM, ie, complete (CHM) and partial (PHM). Both CHM and PHM can recur; however, the recurrence of PHM is very scarce compared to CHM.

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Inflammatory response in COVID-19 contributes greatly to disease severity. Mesenchymal Stem Cells (MSCs) have the potential to alleviate inflammation and reduce mortality and length of stay in COVID-19 patients. We investigated the safety and effectiveness of normoxic-allogenic umbilical cord (NA-UC)-MSCs as an adjunctive treatment in severe COVID-19 patients.

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Background: In Indonesia, the prevalence of cleft lip and palate increased from 0.08% to 0.12% between 2013 and 2018.

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Introduction: Keloid is an abnormal fibroproliferative healing response characterized by excessive and invasive tissue growth beyond the wound boundaries. The conventional treatment involves injecting drugs such as triamcinolone acetonide (TA), 5-fluorouracil (5-FU), or their combination intralesionally. However, the pain associated with injections often leads to low patient compliance and treatment failure.

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