Total synthesis of [β-HIle]-nodupetide: effect of ester to amide substitution on its antimicrobial activity.

The increasing prevalence of deaths due to multidrug-resistant bacteria (MDRB) in infectious disease therapy has become a global health concern. This led to the development of new antimicrobial therapeutic agents that can combat resistance to pathogenic bacteria. The utilization of natural peptide compounds as potential antimicrobial agents is very promising.

Correction: Synthesis and anticancer evaluation of [d-Ala]-nocardiotide A.

[This corrects the article DOI: 10.1039/D4RA00025K.].

Synthesis and anticancer evaluation of [d-Ala]-nocardiotide A.

Cancer is currently one of the biggest causes of death in the world. Like some microorganisms, cancer cells also develop resistance to various chemotherapy drugs and are termed multidrug resistant (MDR). In this regard, there is a need to develop new alternative anticancer agents.