438 results match your criteria: "Universitas Indonesia-Cipto Mangunkusumo Hospital[Affiliation]"

Noninvasive High-Intensity Focused Electromagnetic Therapy in Women With Urinary Incontinence: A Systematic Review and Meta-Analysis.

Neurourol Urodyn

January 2025

Department of Surgery, Division of Urology, Persahabatan General Hospital-Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

Introduction: Urinary incontinence (UI) is an uncontrollable expulsion of urine at a time. UI is obviously not life-threatening, but its impact on the patient's quality of life (QoL) is often devastating. Many treatments method to address this problem but all these methods have limitations.

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Background And Aims: Inhalation anesthetics is basic knowledge that must be mastered by an anesthesiologist. Lack of competencies can result in higher morbidity and mortality in anesthesiology practice. Various learning methods were developed to improve understanding and retention.

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Introduction: Virtual reality-based simulation is an educational tool that has been proven to increase participants' self-perceived, confidence, and skill. However, the use of VR is associated with virtual reality sickness (VRS). The purpose of this study is to determine related factors of VRS in an emergency setting simulation-based training, hence providing information and mitigation plan to enhance and optimize learning outcomes.

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Background/objectives: As people with human immunodeficiency virus experience longer life expectancy, other causes of morbidity and mortality are being increasingly identified. The incidence of non-alcoholic fatty liver disease has recently been on the rise in Indonesia. People with human immunodeficiency virus on antiretroviral therapy are also at an increased risk of having non-alcoholic fatty liver disease.

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Background: Toxoplasmic encephalitis is a severe manifestation of infection, with potentially fatal outcomes, particularly among immunocompromised patients. Clinical manifestation of this infection is associated with a specific genotype of , requiring the use of genetic marker for genotype determination.

Aims: This study critically evaluated the application of GRA6 gene as genetic marker for genotyping in cerebrospinal fluid (CSF) samples from HIV/AIDS patients diagnosed with Toxoplasmic encephalitis.

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Article Synopsis
  • - The ESMO Clinical Practice Guidelines for oncogene-addicted metastatic non-small-cell lung cancer (mNSCLC) were updated into Pan-Asian adapted (PAGA) guidelines to better address the needs of Asian patients.
  • - A panel of experts from multiple Asian oncological societies collaborated to create these guidelines, focusing on scientific evidence rather than local treatment practices or drug availability.
  • - The guidelines aim to standardize the management of oncogene-addicted mNSCLC across Asia, while acknowledging regional differences in screening, treatment resources, and drug reimbursement policies.
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Article Synopsis
  • The study investigates the "obesity paradox" in COPD patients, focusing on how body mass index (BMI) relates to mortality rates.
  • A systematic review of 120 studies showed that while being underweight increases mortality risk, being overweight or obese is associated with lower mortality risk, establishing a U-shaped relationship with BMI.
  • The research highlights specific BMI inflection points where the protective benefits begin to decline, indicating that extremely high BMI values can negate these benefits in relation to various types of mortality.
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Objective: To investigate the relationship between Yes-Associated Protein (YAP) and Vascular Endothelial Growth Factor-A (VEGF-A) in nasopharyngeal carcinoma (NPC) and evaluate their potential as predictive biomarkers for distant metastasis.

Methods: This observational analytic study was conducted from May to August 2023, including 60 NPC cases diagnosed histopathologically at the Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital. The study involved 30 NPC cases with distant metastasis and 30 without distant metastasis.

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Exploring the Potential Treatment for Mpox.

Acta Med Indones

July 2024

Division of Tropical and Infectious Disease, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia..

Monkeypox (Mpox) is a virus that originally infected only animals. Caused by the monkeypox virus, this infection presents with symptoms similar to smallpox. Although two years have passed since the 2022 outbreak, new cases continue to emerge monthly.

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Background:  The COVID-19 pandemic has affected physical and mental health. SLE patients are prone to psychosomatic disorders which can decrease their quality of life. This study aimed to determine the factors associated with psychosomatic disorders among SLE patients during the COVID-19 pandemic.

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Background: Spleen stiffness measurement (SSM) is a recently developed non-invasive method for predicting clinically significant portal hypertension and esophageal varices in compensated advanced liver disease or cirrhosis. This study aims to validate the accuracy of SSM for screening high-risk esophageal varices among cirrhotic patients in Indonesia.

Methods: This is a single-center, cross-sectional study.

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Article Synopsis
  • Febrile neutropenia (FN) is a serious condition often seen in chemotherapy patients, with a notable mortality rate of 12.5%, making accurate risk assessment vital for effective treatment.
  • This study, conducted at Cipto Mangunkusumo Hospital from 2015 to 2019, aimed to compare the effectiveness of two scoring systems—CISNE and MASCC—in predicting complications during hospitalization for FN patients.
  • The results indicated that CISNE score outperformed MASCC in both solid and hematologic cancers, with significant differences in predictive accuracy, particularly highlighting CISNE's superior ability to forecast in-hospital complications.
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Early identification of clinically significant portal hypertension (CSPH) is crucial in cirrhosis, as it is the primary underlying mechanism of cirrhosis complications. One such complication is esophageal varices, which are associated with high morbidity and mortality. Hepatic venous pressure gradient (HVPG) measurements and endoscopy, considered the gold standard for these conditions, are invasive methods that are limited, costly, and inconvenient.

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Background: Carotid intima-media thickness (cIMT) is a measure of atherosclerotic vascular disease and a surrogate biomarker for cardiovascular risk in patients with chronic kidney disease (CKD). Mineral and bone disorders (MBD) are complications of CKD, contributing to vascular calcification and accelerated atherosclerosis. Increased fibroblast growth factor 23 (FGF23)-the earliest detectable serum abnormality associated with CKD-MBD-has been linked with cardiovascular disease in patients with CKD.

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Introduction And Importance: Posttraumatic boutonnière deformities are complex clinical problems that are often poorly understood. Nevertheless, there are no established therapy guidelines, and there is little data to support the various treatment outcomes. In this report, we want to report on the treatment using an ala carte approach of already established procedures.

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Introduction: The incidence of anaplastic transformation of thyroid cancer from Papillary Thyroid Carcinoma (PTC) is a rare tumor event, which ranges from 1 to 2 % of all cases of thyroid malignancy. Anaplastic transformation is often reported in primary lesions, but is rarely found in metastatic lesions from Differentiated Thyroid Carcinoma (DTC).

Presentation Of Case: This case report reports a unique tumor process where a 70-year-old woman had a metastatic lesion in the Mandible from PTC which transformed into ATC with histological features resembling squamous cell carcinoma-type.

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Obstructive sleep apnea: Overlooked comorbidity in patients with diabetes.

World J Diabetes

July 2024

Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, DKI Jakarta, Jakarta Pusat 10430, Indonesia.

In this review article, we explore the interplay between obstructive sleep apnea (OSA) and type 2 diabetes mellitus (T2DM), highlighting a significant yet often overlooked comorbidity. We delve into the pathophysiological links between OSA and diabetes, specifically how OSA exacerbates insulin resistance and disrupts glucose metabolism. The research examines the prevalence of OSA in diabetic patients and its role in worsening diabetes-related complications.

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Introduction: Although studies have indicated comparable outcomes between RFA and surgical resection in early HCC, there is still unclear evidence of benefit in larger tumor sizes. This study aimed to assess the efficacy and safety of RFA versus surgical resection in HCC patients, considering nodule size with a cutoff at 3 cm.

Methods: A comprehensive search of multiple databases was conducted.

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Antimicrobial Resistance Issue: A Matter of Practice and Capacity to Conduct an Audit.

Acta Med Indones

April 2024

Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

The World Health Organization released the practical toolkit for antimicrobial stewardship in health-care facilities in low- and middle-income countries in 2019 due to increasing rates of antimicrobial resistance (AMR) causing the diminishing of treatment options and that the available antibiotics seem to no longer work. The introduction of this toolkit indicates the need to be more down-to-earth in combating the problems of antimicrobial resistance. This situation happened because we have taken antibiotics for granted for too long with less awareness, which results in the potential loss of its use and benefits.

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Periendoscopic Care Continuum in Acute Cholangitis Caused By Common Bile Duct Stone.

Acta Med Indones

April 2024

Division of Gastroenterology, Pancreatobiliary, and Digestive Endoscopy, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia..

Acute cholangitis (AC) is a biliary tract infection with in-hospital mortality rates reaching up to 14.7%. The underlying condition is biliary obstruction caused by benign and malignant etiologies, as well as bacteriobilia, with commom bile duct (CBD) stone being one of the most common causes.

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Background: Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections are global health problems, including in Indonesia. The purpose of this study was to assess the knowledge and attitudes about HBV and HCV infection among infected patients in Indonesia.

Methods: This cross-sectional study used a questionnaire survey.

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Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma in Western countries after diffuse large B-cell lymphoma. Most patients with FL present with asymptomatic disease. Survival rates have been rising over time mainly due to advancing therapeutic strategiesA-51-year-old male with a history of well-controlled diabetes mellitus treated with insulin presented to the policlinic of hematology-medical oncology with worsening right inguinal lymphadenopathy for >3 months.

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Background: Acute lung injury or acute respiratory distress syndrome (ARDS) is one of the most common complications of non-fatal drowning. Although respiratory societies' guidelines endorse the role of systemic corticosteroids in ARDS, the evidence for systemic corticosteroid use in ARDS due to non-fatal drowning is limited.

Methods: A search was conducted on Pubmed, OVID, and EuropePMC, assessing the clinical question using inclusion and exclusion criteria.

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Background And Objectives: , drug-resistant, causes health infections. Resistance to the preferred therapy meropenem is a serious threat. This study aimed to analyze changes in meropenem minimum inhibitory concentration (MIC), changes in and gene expression, and the correlation between MIC and and gene expression after meropenem exposure.

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Introduction: There is a scarcity of long-term follow-up data and management strategies for recurrent uveitis in tubercular uveitis (TBU), especially in cases extending beyond 10 years after the completion of initial antitubercular treatment (ATT).

Methods: This retrospective study involved five TBU patients who were initially treated with a combination of four-drug ATT for 6 months, and the five of them had more than 10 years of follow-up after uveitis resolution upon ATT completion. We describe the occurrence of recurrent uveitis and present our approach to managing these recurrent episodes.

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