Immune responses to SARS-CoV-2 in sub-Saharan Africa and western Europe: a retrospective, population-based, cross-sectional study.

Background: SARS-CoV-2 has been associated with a higher proportion of asymptomatic infections and lower mortality in sub-Saharan Africa than high-income countries. However, there is currently a lack of data on cellular immune responses to SARS-CoV-2 in people living in Africa compared with people in high-income regions of the world. We aimed to assess geographical variation in peripheral and mucosal immune responses.

An expert consensus statement on biomarkers of ageing for use in intervention studies.

Biomarkers of ageing serve as important outcome measures in longevity-promoting interventions. However, there is limited consensus on which specific biomarkers are most appropriate for human intervention studies. This work aimed to address this need by establishing an expert consensus on biomarkers of ageing for use in intervention studies via the Delphi method.

High-performance liquid chromatography method for measuring Captopril: an empirical study on hydrogel film permeability test.

Background: High-performance liquid chromatography (HPLC) has emerged as a highly sensitive and versatile analytical technique for quantifying antihypertensive drugs, such as Captopril (CAP). This study focused on the optimization and validation of an HPLC method for quantifying CAP in an in vitro hydrogel permeability test.

Objectives: The main objective of this study was to develop and validate an HPLC method for quantifying CAP in an in vitro hydrogel permeability test.

Calibration and volunteer testing of a prototype contactless respiratory motion detection system based on laser tracking.

Purpose: The goal of this study was to assess the feasibility of a cost-effective prototype of a laser-based respiratory motion detection system utilizing a Leuze LDS for breath monitoring through calibration and volunteer tests.

Methods: This study was performed using the Anzai AZ-773 V and computerized imaging reference systems (CIRS) motion phantoms for calibration tests. The calibration of the laser-based respiratory motion detection system involved spatial accuracy testing, amplitude calibration, and temporal accuracy.

Technology-assisted Pain Management in Pediatric and Adolescent Burn Care: A Systematic Review and Meta-analysis.

Objective: Burn injuries are one of the leading causes of disability in the pediatric and adolescent population globally. Current practice in pediatric burn management uses opioid analgesics as acute pain management. Technology-assisted pain management, including the application of video games and virtual reality (VR), offers an attractive alternative that can be used to help alleviate pain and anxiety in pediatric and adolescent patients with burns.

The impact of the COVID-19 pandemic in Malaysia, Indonesia, Thailand and Vietnam: insights from the SEANUTS II study.

Objective: To describe the economic, lifestyle and nutritional impact of the COVID-19 pandemic on parents, guardians and children in Malaysia, Indonesia, Thailand and Vietnam.

Design: Data from the SEANUTS II cohort were used. Questionnaires, including a COVID-19 questionnaire, were used to study the impact of the pandemic on parents/guardians and their children with respect to work status, household expenditures and children's dietary intake and lifestyle behaviours.

In-hospital outcomes of acute aortic occlusion treated by endovascular intervention: A single center study.

Background: Endovascular intervention by means of thrombolysis is emerging as a promising management of Acute Aortic Occlusion (AAO). This study aims to evaluate the outcomes of endovascular thrombectomy for AAO cases in a single-center tertiary hospital in Indonesia.

Methods: We review retrospectively AAO patients treated by Rheolytic thrombectomy ± stenting or TEVAR at our referral center from 2011 to 2024.

Problem nutrients in diet of under-five children and district food security status: Linear programming analyses of 37 stunting priority districts in Indonesia.

Background: In Indonesia, food security and dietary patterns varied by regions. This might lead to differences in problem nutrients (PN) and should be considered in developing local-specific food-based recommendations (FBRs) for stunting prevention.

Objectives: This study aims to identify PNs in diet of under-five children in selected 37 stunting priority districts in Indonesia and assess whether the number of PNs was associated with district food security status.

The effect of honey in oral care intervention against chemotherapy-induced mucositis in pediatric cancer patients: a pilot study.

Objective: Mucositis is one of the common side effects of chemotherapy. This study aimed to identify the effects of honey on oral care interventions to reduce mucositis scores among children undergoing chemotherapy.

Methods: This pilot study was quasi-experimental with pre-post intervention with the control group.

The relationship between non-communicable disease risk and mental wellbeing in adolescence: a cross-sectional study utilising objective measures in Indonesia.

Background: Risk factors for non-communicable diseases (NCDs, cardiovascular diseases, cancers, chronic respiratory diseases, diabetes, and mental disorders) arise in adolescence but are mostly framed as relevant to health in adulthood; little is known about the relationship between co-occurring NCD risks and mental wellbeing in young people. This study aims to describe the prevalence and co-occurrence of distinct NCD risk factors, and how they relate to current mental wellbeing amongst adolescents in Indonesia, a young and populous country where NCD burden is increasing rapidly.

Methods: We assessed NCD risk and mental wellbeing amongst 1,331 school-based 16-18-year-olds in Jakarta (N = 609) and South Sulawesi (N = 722).

FoRSHE-X digital health intervention to improve the quality of life during chemotherapy among gynecological cancer survivors in Indonesia: A protocol for a pilot and feasibility study.

Most Indonesian gynecological cancer survivors have unmet supportive care needs during chemotherapy, which may lower their quality of life and discontinue the treatment. Digital health intervention can address this issue. This pilot investigation aims to (1) examine the feasibility and acceptability of a Fighting on distRess, Self-efficacy, Health Effects, and seXual issues (FoRSHE-X) intervention and (2) evaluate prospectively the impact of the study implementation on the level of distress, self-efficacy, side effects' knowledge and management, and sexual quality of life using the RE-AIM (Reach Effectiveness, Adoption, Implementation, and Maintenance) framework.

Comparison of the standard Q syphilis antibody rapid diagnostic test to gold standards for yaws detection in children.

Introduction: Yaws remains a public health problem in Indonesia, and it is the largest contributor to Yaws cases in Southeast Asia. Yaws is caused by bacterial infection of Treponema pallidum subspecies pertenue, mainly affecting the skin and bones. An estimated 75% of new cases were found in children under 15.

Neuropathy among drug resistant HIV Patients treated in Jakarta.

Introduction: Some people living with HIV (PLWH) receiving ART in Indonesia display poor clearance of replicating virus. This has been associated with HIV-associated sensory neuropathy. Here we assess whether treatment failure reflects the presence of drug resistance mutations.

Co-occurrence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients: a multicentre observational study.

Background: The co-occurrence of frailty, sarcopenia and malnutrition has been well studied in inpatient and nursing home settings, which are associated with a higher risk of all-cause mortality. However, multicentre data from community-dwelling outpatient settings are lacking. Therefore, we aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap, and the associated factors in community-dwelling older outpatients.

Advance Care Planning in Palliative Care in Asia: Barriers and Implications.

Advance care planning (ACP) in palliative care is essential for patient autonomy and quality of dying. This review explores ACP practices in South Korea, Japan, and Taiwan, highlighting how legislation and cultural values shape those practices. In these three sectors, which are influenced by Confucian values, family involvement plays a significant role in decision-making.

Electrocoagulation for nickel, chromium, and iron removal from mine water using aluminum electrodes.

High global demand for nickel metal has contributed significantly to the growth of the nickel mining industry in Indonesia. This growth has a positive multiplier effect on the economy, with the potential to affect aquatic life and humans owing to the high levels of chromium, nickel, and iron in mine water. Therefore, this study aims to develop an electrocoagulation (EC) reactor to remove nickel, chromium, and iron from mine water.

Integrating Remote Photoplethysmography and Machine Learning on Multimodal Dataset for Noninvasive Heart Rate Monitoring.

Non-contact heart monitoring is crucial in advancing telemedicine, fitness tracking, and mass screening. Remote photoplethysmography (rPPG) is a non-contact technique to obtain information about heart pulse by analyzing the changes in the light intensity reflected or absorbed by the skin during the blood circulation cycle. However, this technique is sensitive to environmental lightning and different skin pigmentation, resulting in unreliable results.

Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study.

Background: The psychosocial consequences of tuberculosis (TB) are key barriers to ending TB globally. We evaluated and compared stigma, depression, and quality of life (QoL) among people with TB diagnosed through active (ACF) and passive (PCF) case-finding in Nepal.

Methods: We prospectively recruited adults with TB diagnosed through ACF and PCF in four districts of Nepal between August 2018 and April 2019.

Is global health truly global? A hashtag analysis of #GlobalHealth disparities on X.

Background: X (Formerly known as Twitter) healthcare hashtags are a popular healthcare informatics and educational tool among medical professionals. #Globalhealth is one such widely used hashtag with extensive engagement. This study analyses #GlobalHealth to understand its pattern, global digital distribution, and other parameters during the COVID-19 pandemic on X.

Disentangling faculty development: A scoping review towards a rich description of the concept and its practice.

Background: There is wide variation in how faculty development (FD) is practiced globally and described in the literature. This scoping review aims to clarify how FD is conceptualised and practiced in health professions education.

Methodology: Using a systematic search strategy, 418 papers, published between 2015-2023, were included for full text review.

Spontaneous Hall effect induced by collinear antiferromagnetic order at room temperature.

Magnetic information is usually stored in ferromagnets, where the ↑ and ↓ spin states are distinguishable due to time-reversal symmetry breaking. These states induce opposite signs of the Hall effect proportional to magnetization, which is widely used for their electrical read-out. By contrast, conventional antiferromagnets with a collinear antiparallel spin configuration cannot host such functions, because of symmetry (time-reversal followed by translation t symmetry) and lack of macroscopic magnetization.

A Decade of Prevalence and Clinicopathological Insights Into Classical Hodgkin Lymphoma: A Study From an Indonesian Tertiary Hospital.

Background Classical Hodgkin lymphoma (cHL) is a lymphoid malignancy originating from germinal center B cells, predominantly affecting young adults. The clinical profile, histologic subtypes, and immunohistochemical (IHC) patterns play crucial roles in diagnosing cHL and predicting prognosis. This study examines the prevalence, clinicopathological features, and IHC patterns of cHL at Dr.

Cross-Cultural Applications of the New Ecological Paradigm in Protected Area Contexts.

Working mostly in Western, Educated, Industrialized, Rich, and Democratic countries, environmental psychologists have developed scales assessing relationships between pro-environmental beliefs and behaviors. Working in Tanzanian and Indonesian protected area landscapes, containing important biodiversity and conflict over human-nature interactions, we investigate the utility of the New Ecological Paradigm for measuring pro-environmental beliefs and understanding support for protected area regulations. We found the New Ecological Paradigm ineffective at measuring pro-environmental beliefs in both countries; in Tanzania due to acquiescence bias, and in Indonesia exploratory factor analysis supported none of the original factors, with 4 of 15 statements loading onto a novel "eco-fragility" factor.

Multistep Algorithm to Predict RVOT PVC Site of Origin for Successful Ablation Using Available Criteria: A Two-Center Cross-Validation Study.

Background: Predicting premature ventricular contraction (PVC) origin pre-ablation is a fundamental step, as right ventricular outflow tract (RVOT) PVC often leads to higher success rates.

Objective: To compare nine published ECG criteria to differentiate between RVOT and non-RVOT origins of PVCs and develop a stepwise algorithm using those criteria to better determine PVC origin to predict ablation success.

Methods: Two centers were involved in this study, the derivation group and the validation group.