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Universitas Diponegoro[Affiliation] Publications | LitMetric

338 results match your criteria: "Universitas Diponegoro[Affiliation]"

In this study, the potential role and interaction of the and genes on the penetrance of fragile X-associated tremor/ataxia syndrome (FXTAS) and on the IQ trajectory were investigated. FXTAS was diagnosed based on molecular, clinical and radiological criteria. Males with the premutation (PM) over 50 years, 165 with and 34 without an FXTAS diagnosis, were included in this study and were compared based on their () and variant () genotypes.

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Indonesia is suspected as one of the largest plastic waste contributors to the ocean, resulting in microplastic (MP) contamination of the marine environment. Likewise, >250 MP research in Indonesia have been published in the last decade, including review articles. However, a comprehensive review covering MP observations in all areas, i.

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Demographic processes that ensure the recovery and resilience of marine populations are critical as climate change sends an increasing proportion on a trajectory of decline. Yet for some populations, recovery potential remains high. We conducted annual monitoring over 9 years (2012-2020) to assess the recovery of coral populations belonging to the genus Pocillopora.

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Objective: Aim: This study aimed to prove the role of IL-17 on the clinical outcomes of septic patients.

Patients And Methods: Materials and Methods: This study used a systematic review and meta-analysis design. Data were obtained by searching articles published between January 2001 and June 2022 in Pubmed, Science Direct, Scopus, and Medline databases to evaluate Interleukin-17 on clinical outcomes in septic patients.

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Background: The Babon River is one of the drainage channels in Semarang, Indonesia, that is used for drinking water, irrigated agriculture of paddy fields and gardens, fish farming media, and the disposal of industrial wastewater. This study aimed to assess the spatial distribution of metals in the sediment of the Babon River through the utilization of different pollution indices. These indices included concentration factor (Cf), contamination factor (CF), enrichment factor (EF), geoaccumulation index (Igeo), sediment pollution index (SPI), threshold effect level (TEL), and probable effect level (PEL).

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Background: The combined effects of metformin and epigallocatechin-3-gallate (EGCG) on cortisol, 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), and blood glucose levels have not been investigated. This study evaluated the effectiveness of combining EGCG with metformin in regulating those levels in a rat model of diet-induced diabetes and obesity.

Methods: Thirty diabetic and obese rats on a high-fat diet were treated daily for 28 days with EGCG (100 mg/kg of body weight/day), metformin (200 mg/kg of body weight/day), or both.

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Introduction: Delayed graft function (DGF) is a common condition that necessitates dialysis during the first week after transplantation. Although DGF rarely occurs following living-donor kidney transplantation (LDKT), it may eventually lead to acute or chronic graft rejection. This study aimed to assess the risk factors for DGF in patients who underwent LDKT.

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Clinical characteristics of enteric fever and performance of TUBEX TF IgM test in Indonesian hospitals.

PLoS Negl Trop Dis

July 2024

Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Central Jakarta, Indonesia.

Article Synopsis
  • Accurate diagnosis of enteric fever is difficult in low- and middle-income countries due to overlapping symptoms with other illnesses; this study evaluated the effectiveness of the TUBEX TF test in Indonesia.
  • Out of 301 patients clinically diagnosed with enteric fever, only 16.6% were confirmed through blood culture or PCR, with common symptoms including fever and abdominal pain predominantly in school-aged children.
  • The TUBEX TF test showed mixed results, with high sensitivity but low specificity, leading to over-diagnosis; acute IgG testing proved more reliable for identifying true cases of enteric fever.
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Background And Purpose: Breast cancer stem cells (BCSCs) as a kind of tumor cells are able to regenerate themselves, leading to apoptosis resistance and cancer relapse. It was reported that BCSCs contain lower levels of reactive oxygen species (ROS) associated with stemness capability. has been proposed for its chemopreventive potency against several cancer cells.

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Background: Sleep disturbances are included in the six most commonly cited complaints in post-COVID-19 conditions. In order to find the optimal management approach and enhance Quality of Life (QoL), we intend to explore sleep disturbances that occur in post-COVID-19 conditions.

Methods: This was a cross-sectional study conducted with interviews and questionnaires using the Pittsburgh Sleep Quality Index (PSQI) for assessing sleep quality, Insomnia Severity Index (ISI) for assessing insomnia, Epworth Sleepiness Scale (ESS) for assessing Excessive Daytime Sleepiness (EDS), STOP-BANG questionnaire for assessing Obstructive Sleep Apnea (OSA), and Short Form 36 (SF-36) for assessing QoL.

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This study aims to investigate the alteration of salivary biomarker profiling in the development of oral submucous fibrosis (OSMF) and to explore the influence of saliva in the diagnosis of OSMF. A systematic search of published articles using the PRISMA guidelines was conducted to identify relevant studies on OSMF and saliva. All eligible studies, including case-control, cross-sectional studies, cohort, and pilot studies, contained the evaluation of salivary biomarker profiling in patients with OSMF.

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Intermittent fasting modulates human gut microbiota diversity in a phenotype-dependent manner: a systematic review.

Biosci Microbiota Food Health

April 2024

Department of Chemistry and Biochemistry, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jl. Pluit Raya No.2 Jakarta Utara, Jakarta Utara, DKI Jakarta 14440, Indonesia.

Cumulative evidence suggests that intermittent fasting (IF) has beneficial effects on human metabolic health. It has been indicated that its impact on the gut microbiota may mediate these beneficial effects. As a result, we hypothesized that IF may impact the human gut microbiota.

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A new zooxanthellate scleractinian coral, Kishi, Nomura & Fukami, (Scleractinia, Merulinidae), is described from non-coral reef regions of Japan and northern Taiwan. This new species was previously recognized as a morphological variant of (Veron, 1990) and can be morphologically distinguished from that species by lacking groove-and-tube structures on corallite wall joints, and by having larger calices, numerous septa, and up to three corallites in one valley. The new species also formed an independent clade from its congeners, (Milne Edwards & Haime, 1857), and (Wells, 1954), in the molecular phylogeny based on the mitochondrial intergenic region and nuclear ribosomal internal transcribed spacers.

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Background: The COVID-19 pandemic resulted in extreme strain on health systems including the health workforce, essential health services and vaccination coverage. We examined disruptions to immunisation and maternal and child health (MCH) services, concerns of personal well-being and delivery of healthcare during the pandemic as well as factors associated with self-reported trauma or burnout among healthcare providers (HCPs).

Methods: In March-April 2022, we conducted a cross-sectional survey among HCPs in two provinces of Indonesia.

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Objective: This study aimed to identify, discover and explore the characteristics of the mtDNA genomes of Cemani chicken (Gallus gallus).

Methods: This study used gDNA of Cemani chicken isolated from liver tissue. mtDNA sequencing was performed using WGS mtDNA analysis with nanopore technology by Oxford Nanopore Technologies GridION.

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Morphological Changes and Inflammation Preceded the Pathogenesis of 1,2-Dimethylhydrazine-Induced Colorectal Cancer.

Asian Pac J Cancer Prev

June 2024

Department of Histology and Cell Biology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Objective: This study examined the morphological changes in the colonic mucosa and the presence of inflammation in rats induced with 1,2-dimethylhydrazine (DMH) 30 mg/kg BW over 9, 11, and 13 weeks without a latency period.

Methods: Hematoxylin and eosin staining was performed to assess the morphology and characteristic alteration of the epitheliocytes in the colon. Immunohistochemistry was employed to assess the expression of tumor necrosis factor (TNF)-α and cyclooxygenase-2 (COX-2).

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Background: Non-union fractures can be prevented with bone grafts, such as hydroxyapatite made from green mussel shells. Green mussel shells contain a high percentage of HA, making them a promising alternative for bone healing. This research aims to reveal the effectiveness of green mussel shell HA as a bone substitute material and to provide knowledge for further research.

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Background And Aim: The ban on antibiotic growth promoters adversely affects the physiological condition and health of poultry. The aim of this study was to determine the effect of encapsulated L. leaf extract, chitosan, or a combination of both on the physiological and intestinal conditions of broiler chickens.

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Ginger () is a rhizome that has been used as a healthy herbal plant for years. Ginger's chemical components are recognized to provide beneficial health effects, namely as antioxidants and anti-inflammatory agents with the potential to operate as immunomodulators. This literature review covers numerous publications concerning ginger's immunomodulatory potential, associated with antioxidant and anti-inflammatory effects in modifying the body's immune system.

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External and internal factors are involved in controlling the growth of fishes. However, little is known about the mechanisms by which external factors trigger stimulus signals. This study explored the physiological roles of melatonin in the transcription of growth-related genes in the brain and liver of Chrysiptera cyanea, a tropical damselfish with long-day preference.

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The development in human genetics must be tracked with the knowledge to provide support and positive attitudes towards genetic research and its healthcare applications, including genetic testing. Unfortunately, there has been a delay in enacting public policies related to the genetics professionals as well as the diagnosis, treatment, and prevention of genetic diseases in Indonesia. This research was conducted to build an overview of genetic knowledge and public attitudes toward genetic testing among Indonesian undergraduates.

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We conducted a cross-sectional study to describe the health care problems of children with Down syndrome in Central Java, Indonesia. A total of 162 children (81 boys, 81 girls) with Down syndrome were included. Congenital heart defects and hypothyroidism were found in about 50%, followed by vision and hearing problems in 27.

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In recent years, there has been enhanced interest in the domain of natural fibre composites (NFCs) because of their capacity to provide eco-compatible solutions to ever-increasing ecological concerns. This review provides an intensive assessment of the current situation with examination, progress, and applications concerning NFCs. Natural fibres, , jute, kenaf, ramie, banana, coir, wheat grass, , and their scope in the development of sustainable composites, techniques involved in the fabrication of the composites, characterization techniques, , thermo-mechanical and morphological, biodegradability, dampness retention attributes, and potential applications have been extensively reviewed and reported.

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Background: Familial Pancreatic Cancer (FPC) presents a notable risk, with 3-10% of pancreatic adenocarcinoma cases having a family history. Studies link FPC to syndromes like HBOC, suggesting BRCA1/BRCA2 mutations play a role. BRCA gene functions in DNA repair impact FPC management, influencing sensitivity to therapies like PARP inhibitors.

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Stunting remains a significant public health concern, impacting physical growth and impeding children's development. Mothers, who play a crucial role in stimulating children's development, often encounter barriers in providing effective stimulation, primarily due to limited access to appropriate resources and information. Online education can bridge this gap by offering easily accessible learning.

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