Co-occurrence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients: a multicentre observational study.

Background: The co-occurrence of frailty, sarcopenia and malnutrition has been well studied in inpatient and nursing home settings, which are associated with a higher risk of all-cause mortality. However, multicentre data from community-dwelling outpatient settings are lacking. Therefore, we aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap, and the associated factors in community-dwelling older outpatients.

"I'm a Prospective Professional Helper, but I'm Vulnerable": A Mixed Methods Study of the Self-Regulation of Psychology Students with Adverse Childhood Experiences.

Prospective professional helpers particularly in psychology are at great risk when they have had adverse childhood experiences (ACEs). Their self-regulation as survivors may endanger their profession in the future. A mixed-methods sequential explanatory study aimed to gain an in-depth understanding of the self-regulation of emerging adult students majoring in psychology who survived ACEs.

New α-glucosidase inhibitors and antioxidants in optimized Jack leaves extract identified by gC-MS-based metabolomics and molecular docking.

Our earlier research demonstrated α-glucosidase inhibitory (AGI) and antioxidant activities of the optimised extract of leaves. It was reported having numerous compounds, although it was unclear which compounds exhibit the bioactivities as well as their binding interaction to the enzyme. This study aimed to identify the compounds possessing AGI and antioxidant activities in the extract utilising GC-MS-based metabolomics, and to analyse the ligand-enzyme binding interactions molecular docking.

Safety and immunogenicity of a SARS-CoV-2 recombinant protein subunit vaccine adjuvanted with Alum + CpG 1018 in healthy Indonesian adults: A multicenter, randomized, comparative, observer-blind, placebo-controlled phase 2 study.

Globally, dozens of COVID-19 vaccines are licensed under emergency or conditional authorization, but especially in low and middle-income countries, their availability varies. Indonesia decided to become independent and produce its own vaccines locally. This study investigated the safety and immunogenicity of a SARS-CoV-2 recombinant protein subunit vaccine adjuvanted with Alum + CpG 1018.

Ratiometric optical dual gas sensor for simultaneous detection of nitric oxide and oxygen intended for healthcare, biological, and biomedical applications.

Developing efficient and reliable gas sensors for the simultaneous detection of multiple gases is paramount in various fields, specifically healthcare, biological, and biomedical applications. In this study, we present a novel ratiometric optical dual gas sensor based on perovskite quantum dots (PQDs) to detect nitric oxide and oxygen simultaneously. All dye molecules were excited using a 405 nm LED in the experimental setup.

Fatal bear attack in Russian Federation: A case report.

Human-bear conflicts are a growing concern globally, with Russia harboring a significant population of brown bears. This case report details a fatal encounter between a male hunter and a brown bear in the greater Khabarovsk region. On October 2015, the hunter's body was discovered approximately 400 m from a deceased brown bear, indicating a deadly confrontation.

Alumina-enriched sunflower bio-oil in machining of Hastelloy C-276: a fuzzy Mamdani model-aided sustainable manufacturing paradigm.

With the increasing emphasis on sustainable manufacturing practices, eco-friendly lubricants have gained significant attention to moderate the friction coefficient at the tool-work interface. In line with this, the contemporary study aimed to examine the viability of Alumina-enriched sunflower bio-oil as a metalworking fluid. Different volume fractions of Alumina nanoparticles (varying from 0 to 1 vol%) were mixed with sunflower bio-oil, and the physical properties, for instance, contact angle and dynamic viscosity, were analyzed to determine the optimal concentration of Alumina.

Weighted Vest Combined With Vibrotactile Stimulations Decrease the Sympathetic Activity: A Repeated Measures Study.

Background And Aims: Mental and neurological disorders are a growing global concern, further intensified by the COVID-19 pandemic. Stress management techniques, such as deep pressure therapy, have gained attention, with weighted vests commonly used for anxiety relief. However, there is limited scientific evidence supporting their efficacy.

Enhancing accessibility: Development and usability testing of mobile application mitigating sexual harassment for visually impaired masseurs.

This study aimed to assess the development and usability of the Visually Impaired Masseur Assistance Application (VIMAA) designed to respond to signs of danger or instances of sexual harassment experienced by Visually Impaired Masseurs (VIMs). It harmonizes Rapid Application Development (RAD) method and qualitative in-depth interviews. RAD was implemented with emphasis on four core stages: requirement identification, design workshop, construction, and implementation, while Qualitative in-depth interviews were conducted utilizing thematic analysis for usability testing.

The level of confidence of dentists in identifying intact and sectioned teeth.

Objective: This study aimed to assess the confidence levels of dentists in identifying intact and sectioned human teeth and to identify the factors contributing to variations in confidence levels.

Design: An anonymous Jisc e-survey showing 14 questions was sent to dentists worldwide. Apart from acquiring demographic details of the participants, ten three-dimensional (3D) tooth models were presented for tooth identification including the opinion on the level of confidence in identifying.

Betel Quid Use and Tuberculosis Transmission: A Neglected Focus Area for Tuberculosis Control in Low- and Middle-Income Countries.

Habitual betel quid consumption and spitting contribute to tuberculosis (TB) transmission due to direct exposure to pathogens, immunosuppression, and social contact. Despite betel quid being classified as a group 1 human carcinogen and a high prevalence of betel quid consumption in patients with TB, there exists a knowledge gap in the relationship between quid use and TB, which presents as a neglected opportunity to address the global burden of TB in low- and middle-income countries. Understanding such a knowledge gap is crucial when taking measures at various levels, including research prioritization, behavior change communication, and legislation to address the availability and access of quid products, coupled with community-based interventional strategies.

Expanding the occurrence of antimalarial metabolites in dorid nudibranch Hypselodoris tryoni.

This study examined the antimalarial activity of a furanosesquiterpene, furodysinin, one of the major metabolites of the dorid nudibranch Hypselodoris tryoni. The nudibranchs were collected from Balinese waters and the metabolites were purified by chromatography. Ex vivo rodent malaria Plasmodium berghei assays were conducted to determine the metabolite antimalarial activity.

Development and psychometric evaluation of the Employee's Workplace Cyberloafing Scale (EWCS).

Cyberloafing refers to the practice of employees using the Internet for non-work-related purposes during working hours. This study aims to develop a measurement scale for cyberloafing among employees, specifically those working in Indonesia. The research was conducted in two stages.

Effectiveness and Safety of DLBS3233 in Newly Diagnosed Type 2 Diabetes Mellitus: A 12-week Clinical Trial.

Background: DLBS3233, recognized as an agent enhancing insulin sensitivity, has exhibited promise as a therapeutic option for addressing type 2 diabetes mellitus (T2DM). This study aimed to evaluate the effectiveness and safety of DLBS3233, a natural compound, in individuals newly diagnosed with T2DM.

Methods: A 12-week double-blind, randomized, placebo-controlled clinical trial was conducted with 104 eligible participants.

Meningomyelocele Perioperative Management in Neonatal: Case Series.

Background: Myelomeningocele (MMC) is a congenital malformation affecting the central nervous system, categorized as a neural tube defect (NTDs). In untreated cases, the mortality rate within the first six months of life ranges from 35% to 70%. Globally, its incidence is estimated 0.

Influence of suspended cenospheres on the mechanical characteristics and wear loss of natural fiber-reinforced hybrid composites: implications for biomedical applications and sustainable material management.

The need for non-conventional natural fibres for synthesis of hybrid composites has gained momentum in the recent past. Taking into consideration this need, in the current study, hybrid composites were fabricated by reinforcing wood apple shell powder and coconut shell powder, in the resin with varying amounts of cenospheres (up to 20 wt% in increments of 5 wt%) to evaluate their mechanical and tribological properties. The densities of these composites were directly correlated with the quantity of additives utilized.

Technological Innovation in International Training and Advancing Health Services: Two Cases During the COVID-19 Pandemic.

Beginning in 2020, the COVID-19 pandemic limited onsite international activities and challenged us to plan and implement new ways of collaboration. We reviewed our online trials during a three-year period to better understand how to use digital technologies to continue knowledge and skills transfer. In this cross-national case study, we compare two illustrative cases: Japanese experts training Indonesian health professionals for participatory school health education, and Swiss experts training Malagasy health providers for respectful obstetric and newborn emergencies.

Constructed wetlands combined with microbial fuel cells (CW-MFCs) as a sustainable technology for leachate treatment and power generation.

The physical and chemical treatment processes of leachate are not only costly but can also possibly produce harmful by products. Constructed wetlands (CW) has been considered a promising alternative technology for leachate treatment due to less demand for energy, economic, ecological benefits, and simplicity of operations. Various trends and approaches for the application of CW for leachate treatment have been discussed in this review along with offering an informatics peek of the recent innovative developments in CW technology and its perspectives.

Comparing health-related quality of life and utility scores of patients undergoing hemodialysis and continuous ambulatory peritoneal dialysis in Indonesia.

Background: Although both hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) are covered by national healthcare insurance, 98% of kidney failure disease patients are treated with hemodialysis. This study compared the health-related quality of life (HRQoL) and utility scores of patients receiving hemodialysis and CAPD in Indonesia and determined factors associated with HRQoL and utility scores.

Methods: A cross-sectional study was performed using the Kidney Disease Quality of Life-36 and EQ-5D-5L instruments at six hospitals.

The radiographic diversity of dental patterns among 7219 young individuals-a contribution to disaster victim identification.

The diversity of dental patterns is a fundamental topic in disaster victim identification. The current scientific literature, however, is scarce of data regarding young individuals. This study aimed to assess the radiographic diversity of dental patterns, considering missing, unrestored, and filled teeth in young individuals.