Deep Vein Thrombosis as a Complication of Gemcitabine-Capecitabine Chemotherapy in Adenocarcinoma of Gallbladder.

Gallbladder adenocarcinoma has a high mortality rate, with approximately 1.7% cancer-related deaths worldwide. Cancer-associated thrombosis (CAT), including deep vein thrombosis (DVT), can significantly increase the risk of mortality within cancer patients, especially in pancreatic, brain, and intra-abdominal cancers, as well as in advanced and metastatic cancers.

A novel floating adsorbent for cesium based on Shirasu balloon modified with magnetite and Prussian blue.

Shirasu balloon (SB) is a hollow glassy sphere produced from volcanic deposits by heating that can float up on water owing to its hollow structure. In this study, a novel adsorbent for the removal of cesium ion in water was developed by the modification of the surface of the SBs with magnetite (Mag) and Prussian blue (PB). The developed adsorbent (PB-Mag-SB) was characterized by elemental analysis, X-ray diffraction, and Fourier transform infrared spectrometry and the magnetism of the adsorbent.

The effect of varying thicknesses of mineral trioxide aggregate (MTA) and Biodentine as apical plugs on the fracture resistance of teeth with simulated open apices: a comparative study.

Background: This study evaluates the fracture resistance of apical plugs created from Biodentine and mineral trioxide aggregate (MTA) in thicknesses of 3 and 5 mm within simulated open apex tooth models.

Methods: Fifty human maxillary central incisors were obtained from a pool of freshly extracted teeth. In order to replicate open apices without cavity preparation, ten teeth in the control group received apical-to-coronal preparation with Peeso reamers.

Husband's Contributions to Stimulate Wife's Confidence Experiencing Role Transition: Cross-Sectional Study.

Introduction: Pregnancy can cause various physical and physiological changes. It affects confidence, resulting in depression and disturbing health not only for a mother but also for her fetus. These will also determine the ability of the mother to take care of her baby after delivery.

Structural heart disease in the tropics: A comprehensive review.

Structural heart disease (SHD) remains a significant global health challenge, disproportionately impacting populations in tropical regions where the burden of infectious diseases, limited healthcare infrastructure, and socio-economic disparities exacerbate the issue. The tropics are uniquely affected by conditions such as rheumatic heart disease (RHD), endomyocardial fibrosis, tropical cardiomyopathies, and pericardial diseases, often resulting from or complicated by endemic infections like malaria, dengue, tuberculosis, and parasitic diseases. Moreover, Human Immunodeficiency Virus-Associated Cardiac Disease (HIVAC) represents an emerging concern in regions with high HIV prevalence, adding complexity to the interplay between infectious and structural cardiac conditions.

Evidence of microcystin bioaccumulation and its effects on structural alterations in various shrimp (Litopenaeus vannamei Boone, 1931) tissues from shrimp aquaculture in the northern coastal region of East Java, Indonesia.

Microcystins are generated by diverse cyanobacteria in shrimp ponds marked by high nutrient levels. The study examined microcystin-leucine arginine (MC-LR) in the pond water, gills, hepatopancreas, and muscle of shrimp (Litopenaeus vannamei) from shrimp ponds on the northern coast of East Java and its effects on their histological structures. In shrimp ponds dominated by cyanobacteria particularly Microcystis and Oscillatoria, MC-LR levels were high.

Therapeutic potential of Indonesian plant extracts in combating malaria and protozoan neglected tropical disease.

Background: Neglected tropical diseases (NTDs) afflict nearly 2 billion people worldwide and are caused by various pathogens, such as bacteria, protozoa, and trypanosoma, prevalent in tropical and subtropical regions. Among the 17 NTDs recognized by the World Health Organization (WHO), protozoal infections caused by Plasmodium, Entamoeba, Leishmania, and Trypanosoma are particularly prominent and pose significant public health. Indonesia, endowed with a rich biodiversity owing to its tropical climate, harbors numerous plant species with potent biological activities that hold promise for therapeutic interventions.

Periprosthetic joint infections: state-of-the-art.

In general, periprosthetic joint infection (PJI) is regarded as one of the most common complications of total joint arthroplasty (TJA) and may lead to surgical failure, revision surgery, amputation or death. Nowadays, PJI has become a global health concern, which brings a great burden to public healthcare. In addition, there are still obstacles to achieve high success rates in the prevention, diagnosis and treatment of PJI.

The effect of vitamin D in vitro supplementation on sperm deoxyribonucleic acid fragmentation.

Objective: This study aimed to identify the direct effect of vitamin D on sperm DNA integrity after swim-up preparation.

Materials And Methods: Normozoospermia samples were gathered from 12 men and assessed for their baseline characteristics, including DNA Fragmentation Index (DFI). Each sample was then prepared using the swim-up method.

Co-occurrence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients: a multicentre observational study.

Background: The co-occurrence of frailty, sarcopenia and malnutrition has been well studied in inpatient and nursing home settings, which are associated with a higher risk of all-cause mortality. However, multicentre data from community-dwelling outpatient settings are lacking. Therefore, we aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap, and the associated factors in community-dwelling older outpatients.

Umbilical cord mesenchymal stem cells improve bone regeneration in diabetes mellitus animal model with apical periodontitis.

Background: Previous studies revealed diabetes mellitus subjects tend to have persistent apical periodontitis. Regenerative stem cells therapy through endodontic procedure is hoped to be a solution. This study assessed bone regeneration in diabetic rats with apical periodontitis through histopathological analysis of osteoblasts and immunohistochemical analysis of runt-related transcription factor 2 (Runx2) and Osterix.

The association between fibroblast growth factor 21 with diabetes retinopathy among type 2 diabetes mellitus patients: a systematic review, meta-analysis, and meta-regression.

Background: Diabetic retinopathy (DR), a leading cause of vision loss worldwide, is a common complication of type 2 diabetes mellitus (T2DM) driven by chronic hyperglycemia and microvascular damage. Fibroblast growth factor 21 (FGF21) is crucial in blood sugar regulation and has been linked to DR incidence and severity. While some studies suggest that FGF21 levels may contribute to the DR incidence, others propose a protective role.

Experimental Investigation of the Optical Nonlinearity of Laser-Ablated Titanium Dioxide Nanoparticles Using Femtosecond Laser Light Pulses.

In this report, the nonlinear optical (NLO) properties of titanium dioxide nanoparticles (TiO NPs) have been explored experimentally using femtosecond laser light along with the Z-scan approach. The synthesis of TiO NPs was carried out in distilled water through nanosecond second harmonic Nd:YAG laser ablation. Characterization of the TiO NPs colloids was conducted using UV-visible absorption spectroscopy, transmission electron microscopy (TEM), inductively coupled plasma (ICP), and energy-dispersive X-ray spectroscopy (EDX).

Oral Health Status and Oral Healthcare System in Indonesia: A Narrative Review.

Aim: To assess the current situation regarding oral health status and system in Indonesia through the existing literature and government documents, identify challenges, and propose recommendations for the future.

Materials And Methods: A literature search was conducted from June to October 2023 through the scientific databases of PubMed, Web of Science, and Google Scholar, including published articles from 2013 to 2023. The following main keywords were used: "Indonesia," "oral health system," "oral healthcare system," "oral health policy," "oral health promotion," "oral health coverage," and "oral health status.

Overview of ICU Nurses' Knowledge and Need Assessment for Instrument to Detect Sick Building Syndrome.

Introduction: Nurses in intensive care units (ICUs) are vulnerable to sick building syndrome (SBS), which can affect their health, performance, and patient safety. Understanding SBS is crucial in healthcare to protect both staff and patients. However, many ICU nurses lack knowledge about this condition and the necessary detection tools.

Ocean wave prediction using Long Short-Term Memory (LSTM) and Extreme Gradient Boosting (XGBoost) in Tuban Regency for fisherman safety.

The fishing industry has a large role in the Indonesian economy, with potential profits in 2020 of around US$ 1.338 billion. Tuban Regency is one of the regions in East Java that contributes to the fisheries sector.

Review of mayflies (Insecta Ephemeroptera) as a bioindicator of heavy metals and microplastics in freshwater.

Heavy metal and microplastic pollutions are prevalent in freshwater ecosystems, with many freshwater bodies being contaminated by one or both of these pollutants. Recent studies reported extreme detections of Cd, Pb and Zn, high concentrations of Cr, Pb and Cu and microplastics acting as vectors of pollutants, including heavy metals. Mayflies can serve as bioindicators of heavy metal contamination in freshwater ecosystems because changes in their community structure, physiology, and behaviour can reflect and help predict the concentrations of metals in these environments.

Cost effectiveness of empagliflozin in adult patients with chronic kidney disease in the Netherlands.

Aim: The recent EMPA-KIDNEY trial showed evidence for preventing disease progression in adult patients with chronic kidney disease (CKD) treated with empagliflozin. It is however yet unknown if use of empagliflozin is cost effective in the Netherlands. We aimed to evaluate the cost effectiveness of empagliflozin in adult patients with CKD in the Netherlands.

Nutritional fulfillment behavior of pregnant women based on the health belief model theory in Indonesia.

Introduction: malnutrition in pregnant women will cause impaired fetal development, premature delivery, impaired baby growth, and the risk of causing chronic disease. The Health Belief Model is used and has an important role in directing pregnant women to engage in preventive health behavior, namely preventing malnutrition.

Objective: this study aims to analyze the factors related to the nutritional fulfillment behavior of pregnant women based on the theory of the health belief model.

Unusual G9P[4] Rotavirus Emerged After the Dynamic Changes in Rotavirus Genotypes From Equine-Like G3 to Typical Human G1/G3 in Indonesia.

Inter-genogroup reassortment of Rotavirus A (RVA) strains has highlighted the spread of unusual RVA strains worldwide. We previously reported the equine-like G3 RVA as the predominant strain in Indonesia in 2015-2016. However, since July 2017, typical human genotypes G1 and G3 have replaced these strains completely.

Insights into in vitro and in silico studies of α-glucosidase inhibitors isolated from the leaves of Grewia optiva (Malvaceae).

α-Glucosidase plays a critical role in glucose metabolism by breaking down complex carbohydrates into simpler sugars for intestinal absorption. Due to the side effects of current α-glucosidase inhibitors, there is increasing interest in exploring alternative therapeutic options. Inspired by the traditional uses of Grewia optiva J.

Fabrication and evaluation of breast tissue equivalent phantoms for image quality assessment in ultrasound imaging.

Introduction: Phantom materials with tissue-equivalent physical properties that require regular evaluation using patented phantoms are essential for medical device quality assurance programs. This study evaluated phantom materials for tissue equivalence and their use in image quality assessment for breast ultrasound scanner performance testing using two custom-made phantoms.

Methods: Two types of phantoms were developed: phantoms A and B.