19 results match your criteria: "Universitaire Ziekenhuizen Gasthuisberg[Affiliation]"
JMIR Mhealth Uhealth
March 2019
e-Media Research Lab, Katholieke Universiteit Leuven, Leuven, Belgium.
Background: Patients with chronic arthritis (CA) ideally apply self-management behaviors between consultations. This enduring, tedious task of keeping track of disease-related parameters, adhering to medication schemes, and engaging in physical therapy may be supported by using a mobile health (mHealth) app. However, further research is needed to determine which self-management features are valued most by adult patients with CA patients.
View Article and Find Full Text PDFTransplantation
March 2017
1 Starzl Abdominal Transplant Unit, University Hospitals St. Luc, Université catholique Louvain, Brussels, Belgium. 2 Centre Hépatobiliaire Paul Brousse, Paris, France. 3 Medizinsche Hochschule Hannover, Hannover, Germany. 4 Transplancenter IKEM, Prague, Czech Republic. 5 Istituto Nazionale Tumori, Milano, Italy. 6 Charité Campus Virchow Klinikum, Berlin, Germany. 7 Department of General Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland. 8 UCJ Helsingfors, Helsinki, Finland. 9 Department Abdominal transplantation Surgery, Universitaire Ziekenhuizen Gasthuisberg KULeuven, Belgium. 10 Rikshospitalet, Oslo Universitetssykehus, Oslo, Norway. 11 Karolinska University Hospital, Huddinge, Stockholm, Sweden. 12 University Medical Centre Ljubljana, Ljubljana, Slovenia.
Background: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare vascular tumor which has an intermediate aggressive behavior. Although the value of liver transplantation (LT) is well established, its place in the management of HEHE is still unclear. The aim of this study is to confirm, based on a very large patient cohort, the value of LT in the management of HEHE and to identify risk factors for post-LT recurrence.
View Article and Find Full Text PDFJ Thorac Cardiovasc Surg
July 2015
Cardio-Thoracic Department, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
Objective: A prospective trial was designed to evaluate the feasibility of the Perceval sutureless aortic valve. We report the 5-year clinical and hemodynamic outcome.
Methods: A total of 30 patients (mean age: 80.
Clin Infect Dis
August 2015
Pfizer Pharma GmbH, Berlin, Germany.
Background: Life-threatening Streptococcus pneumoniae infections often occur after hematopoietic stem cell transplant (HSCT); vaccination is important for prevention.
Methods: In an open-label study, patients (n = 251) 3-6 months after allogeneic HSCT received 3 doses of 13-valent pneumococcal conjugate vaccine (PCV13) at 1-month intervals, a fourth dose 6 months later, and 1 dose of 23-valent pneumococcal polysaccharide vaccine (PPSV23) 1 month later. Immunogenicity at prespecified time points and vaccine safety were assessed.
Transplantation
July 2004
Inwendige Geneeskunde-Nefrologie, Universitaire Ziekenhuizen Gasthuisberg, Leuven, Belgium.
Background: In animal and in vitro models, FK778 inhibits acute rejection, modifies vasculopathy, and shows anti-viral activity. We report first efficacy and safety data of FK778 in human kidney transplant recipients at two concentration-controlled ranges.
Methods: In a double-blind manner, 149 patients were randomized to a 12-week treatment with FK778 in combination with tacrolimus (Tac) and corticosteroids (S).
J Nucl Med
December 2003
Laboratory for Radiopharmaceutical Chemistry and Department of Nuclear Medicine, Universitaire Ziekenhuizen Gasthuisberg, Leuven, Belgium.
Unlabelled: Three omega-(18)F-fluoro-n-alkyl-beta-D-glucosides (alkyl = ethyl (5a)), n-butyl (5b), and n-octyl (5c)) were synthesized and evaluated as potential substrates for the sodium/D-glucose cotransporter SGLT1.
Methods: The ligands were prepared by (18)F-fluoride displacement of the corresponding tetraacetyl-protected tosylate alkylglucoside precursors in CH(3)CN, followed by hydrolysis of the protective acetate esters with NaOMe/MeOH. Transport of the nonradioactive analogs 5a, 5b, and 5c by the human sodium-D-glucose cotransporter hSGLT1 was characterized in vitro in oocytes of Xenopus laevis that expressed hSGLT1.
J Clin Endocrinol Metab
April 2002
Laboratory and Clinic of Experimental Medicine and Endocrinology, Universitaire Ziekenhuizen Gasthuisberg, B-3000 Leuven, Belgium.
Fluorodeoxyglucose (FDG) whole body positron emission tomography (PET) scan is increasingly used in the diagnostic work-up or follow-up of patients. In these conditions, positive PET scans with unexpected hot spots within the thyroid region could be defined as thyroid FDG-PET incidentaloma (in analogy with unexpected sonographic thyroid nodules). We describe eight consecutive patients referred to the endocrine department because of thyroid "hot spots," incidentally detected by whole body FDG-PET scan (September 1999 to March 2001).
View Article and Find Full Text PDFJ Belge Radiol
October 1998
Dienst Radiologie, Heelkunde Universitaire Ziekenhuizen Gasthuisberg Leuven.
A case is presented of a primary extragonadal retroperitoneal germ cell tumor (seminoma) in a 51-year-old male. The ultimate diagnosis was only achieved after curative surgical resection of the tumor. There was no demonstrable testicular neoplasm.
View Article and Find Full Text PDFClin Endocrinol (Oxf)
October 1998
Laboratory and Clinic of Experimental Medicine and Endocrinology, Universitaire Ziekenhuizen Gasthuisberg, Leuven.
We report on a woman with clinical Cushing's syndrome confirmed by biochemical data. The Cushing's syndrome was shown to be ACTH dependent and inferior petrosal sinus sampling pointed to an ectopic source. After resection of a lung carcinoid a well documented remission of Cushing's syndrome was obtained.
View Article and Find Full Text PDFJ Anesth
March 1997
Department of Anesthesiology, Yamanashi Medical University, 1110 Shimokato, Nakakoma-gun, 409-38, Yamanashi, Japan.
Using an implanted Doppler crystal, we evaluated emodynamic changes induced by subconvulsive doses of bupivacaine and lidocaine in awake and pentobarbitalanesthetized rats. Low doses of lidocaine (2.0 mg·kg) and bupivacaine (0.
View Article and Find Full Text PDFActa Clin Belg
June 1997
Afdeling Lever- en pancreasziekten, Dienst Inwendige Geneeskunde, Universitaire Ziekenhuizen Gasthuisberg, Leuven.
Following the discovery in 1989 of the hepatitis C virus (HCV), sensitive and specific diagnostic assays have shown the involvement of this RNA virus in a myriad of liver disease and extrahepatic pathology. The genetic heterogeneity of HCV is an exciting challenge in the field of epidemiology, diagnosis, treatment and vaccine development. Although viral eradication has not been achieved in the majority of patients by using interferon as single agent, the combination with ribavirin seems to have a better outlook.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
March 1996
Department of Obstetrics and Gynecology, Universitaire Ziekenhuizen Gasthuisberg, Catholic University of Leuven, Belgium.
To increase our understanding of the nature and source of immunoreactive inhibin-related material during pregnancy, we studied inhibin secretion in women pregnant after spontaneous conception and after in vitro fertilization (IVF). Two solid phase enzyme-amplified immunoassays (EASIAs) were used to measure the inhibin A dimer and inhibin alpha-subunit immunoreactivities (alpha-inhibin). In spontaneous pregnancies, levels of both inhibin A and alpha-inhibin were low during the first two trimesters of pregnancy, but a significant increase was observed toward the end of gestation.
View Article and Find Full Text PDFBasic Res Cardiol
September 1996
Department of Anesthesiology, Universitaire Ziekenhuizen Gasthuisberg, Katholieke Universiteit Leuven, Belgium.
Both the severity and duration of postischemic myocardial dysfunction ("stunned" myocardium) are unpredictable and may vary considerably between subjects that underwent apparently similar ischemic insults. To explain this heterogeneous response of the heart to ischemia and reperfusion, we investigated the determinants of stunning in conscious dogs. Twenty-five dogs were chronically instrumented for measurement of global and regional myocardial performance (wall thickening) and myocardial perfusion (coloured microspheres).
View Article and Find Full Text PDFEur J Anaesthesiol
September 1994
Department of Anaesthesiology, Universitaire Ziekenhuizen Gasthuisberg, Leuven, Belgium.
The haemodynamic effects of urapidil, an alpha 1-antagonist with central serotoninergic properties, were studied in an experimental canine model of chronic ischaemic heart disease. Global and regional haemodynamic recordings were made in conscious dogs with ameroid-induced single vessel coronary artery occlusion. Three intravenous bolus-infusion doses of urapidil (0.
View Article and Find Full Text PDFGenet Couns
August 1994
Department of Internal Medicine (Division of Gastroenterology), Universitaire Ziekenhuizen Gasthuisberg, Leuven, Belgium.
Tijdschr Kindergeneeskd
June 1993
Dienst Kindergeneeskunde, Universitaire Ziekenhuizen Gasthuisberg K.U. Leuven, België.
Two siblings with esophageal atresia are reported, and literature data as to familial occurrence and heredity have been reviewed. Until now, only statistical data can be given: the recurrence risk for sibs after one affected child is around 0.5-2% and after two affected children around 20%.
View Article and Find Full Text PDFGastroenterology
August 1990
Department of Medical Research, Universitaire Ziekenhuizen Gasthuisberg, Leuven, Belgium.
It is generally accepted that biliary secretion is rate-limiting for the plasma-to-bile transport of a saturating load of bilirubin. Previous studies from this laboratory have suggested a relationship between the hepatic bilirubin uridine diphosphate glucuronosyltransferase activity and the apparent maximal rate of bilirubin secretion (excretory transport maximum). The present study was undertaken to further investigate this relationship in rats with a wide range of transferase levels and to analyze the effects of transferase activity on the formation of bilirubin monoglucuronides and diglucuronides in vivo and in vitro.
View Article and Find Full Text PDFJ Appl Physiol (1985)
May 1989
Laboratorium voor Longfunktieonderzoek, Universitaire Ziekenhuizen Gasthuisberg, Leuven, Belgium.
Because of the contradictory statements published about the influence of the shunt properties of the upper airway on the measurements of the respiratory impedence by means of the forced oscillation technique, this influence has been reevaluated. In healthy adults and children and in patients with obstructive lung disease, the total respiratory impedance was measured by applying oscillations at the mouth (conventional technique) or around the head (head generator technique), with the cheeks either supported by the hands or not. In healthy adults the two techniques (conventional cheeks supported and head generator) yield similar results for respiratory resistance (Rrs) and a more pronounced increase of respiratory reactance (Xrs) with frequency with the head generator.
View Article and Find Full Text PDFNeurofibromatosis
June 1990
Centrum voor Menselijke Erfelijkheid, Universitaire Ziekenhuizen Gasthuisberg, Leuven, Belgium.