Overweight and Obese Children Aged 6-17 Years in China Had Lower Level of Hydration Status: A Cross-Sectional Study.

Purpose: The aims of this study were to explore the differences in total body water and hydration status among Chinese children aged 6-17 years.

Methods: A cross-sectional study was implemented among children aged 6-17 years in China. The total body water (TBW), intracellular water (ICW), and extracellular water (ECW) were determined by bioelectrical impedance analysis (BIA).

Acoustic, Mechanical, and Thermal Characterization of Polyvinyl Acetate (PVA)-Based Wood Composites Reinforced with Beech and Oak Wood Fibers.

Considering the growing need for developing ecological materials, this study investigates the acoustic, mechanical, and thermal properties of wood composites reinforced with beech or oak wood fibres. Scanning electron microscopy (SEM) revealed a complex network of interconnected pores within the composite materials, with varying pore sizes contributing to the material's overall properties. Acoustic characterization was conducted using a two-microphone impedance tube.

The Application of Supervised Machine Learning Algorithms for Image Alignment in Multi-Channel Imaging Systems.

This study presents a method for aligning the geometric parameters of images in multi-channel imaging systems based on the application of pre-processing methods, machine learning algorithms, and a calibration setup using an array of orderly markers at the nodes of an imaginary grid. According to the proposed method, one channel of the system is used as a reference. The images from the calibration setup in each channel determine the coordinates of the markers, and the displacements of the marker centers in the system's channels relative to the coordinates of the centers in the reference channel are then determined.

Diagnostic Challenges of Medullary Carcinoma of the Small Intestine During the COVID-19 Pandemic.

: Medullary carcinoma of the small intestine is an exceptionally rare subtype of gastrointestinal cancer, characterized by its solid growth pattern and lack of glandular structures, which complicate timely diagnosis. During the COVID-19 pandemic, diagnostic delays for rare cancers became increasingly common due to the prioritization of COVID-related cases and patient reluctance to seek medical attention. : We present the case of a 70-year-old male initially misdiagnosed with COVID-19, whose persistent symptoms led to the eventual discovery of medullary carcinoma.

Changes in the Content of Dietary Fiber, Flavonoids, and Phenolic Acids in the Morphological Parts of (L.) Gaertn Under Drought Stress.

Background: Tartary buckwheat is a plant recognized for its resistance to various environmental stresses. Due to its valuable source of phenolic compounds, is also characterized as a medicinal plant; therefore, the aim of this study was to investigate the drought stress for the levels of phenolic compounds in the morphological parts of the plant.

Methods: This experiment was conducted in 7 L pots under laboratory conditions.

Terbium-Labeled Gold Nanoparticles as Nanoscale Brachytherapy Agents Against Breast Cancer.

Due to their intriguing emission profile, Terbium-161 (Tb) radiopharmaceuticals seem to bring significant advancement in theranostic applications to cancer treatment. The combination of Tb with nanoscale brachytherapy as an approach for cancer treatment is particularly advantageous and promising. Herein, we propose the application of a hybrid nanosystem comprising gold decorated (Au@TADOTAGA) iron oxide nanoflowers as a form of injectable nanobrachytherapy for the local treatment of breast cancer.

Viability and Radiosensitivity of Human Tumor Cells from Breast and Colon Are Influenced by Extract HP01.

To enhance the treatment of tumors that are resistant to radio- and chemotherapy while minimizing the side effects of radiochemotherapy, researchers are continuously seeking new active compounds for use in combination with radiotherapy. Therefore, the aim of our study was to examine the cytotoxic and radiosensitizing effects of an extract from St. John's Wort (, referred to as HP01, on human epithelial tumor cells in vitro.

A Systematic Review of Microbiota in Cirrhosis: A Change Towards a More Pathogenic Predisposition.

The microbiome of the human intestine is a regulator of health that modulates immune response and plays an important role in metabolism. The diversity, and abundance of microbiota communities in the gut have been shown to change in cirrhosis and its complications. We aimed to review the current knowledge regarding microbiota alterations in cirrhosis, its potential differences according to etiology, and its role in the development of cirrhosis complications.

Recombinant Production of Bovine α-Casein in Genome-Reduced Strain IIG-Bs-20-5-1.

Background: Cow's milk represents an important protein source. Here, especially casein proteins are important components, which might be a promising source of alternative protein production by microbial expression systems. Nevertheless, caseins are difficult-to-produce proteins, making heterologous production challenging.

Editorial for the Special Issue on Micromachined Acoustic Transducers for Audio-Frequency Range.

Microelectromechanical systems (MEMS) refer to miniaturized mechanical and electro-mechanical elements that are fabricated through microelectronic processes [...

History of Biological Databases, Their Importance, and Existence in Modern Scientific and Policy Context.

With the development of genome sequencing technologies, the amount of data produced has greatly increased in the last two decades. The abundance of digital sequence information (DSI) has provided research opportunities, improved our understanding of the genome, and led to the discovery of new solutions in industry and medicine. It has also posed certain challenges, i.

Comparative Efficacy and Safety of Cardio-Renoprotective Pharmacological Interventions in Chronic Kidney Disease: An Umbrella Review of Network Meta-Analyses and a Multicriteria Decision Analysis.

Sodium-glucose co-transporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP1a), and non-steroidal mineralocorticoid receptor antagonists (ns-MRA) are promising treatments for chronic kidney disease. This umbrella review of network meta-analyses evaluated their effects on cardiovascular outcomes, kidney disease progression, and adverse events, using the TOPSIS method to identify the optimal intervention based on P-scores. A total of 19 network meta-analyses and 44 randomized controlled trials involving 86,150 chronic kidney disease patients were included.

Radiographic and Clinical Results of Combined Bone and Soft-Tissue Tailored Surgeries for Hip Dislocation and Subluxation in Cerebral Palsy.

Background/objectives: The aim of the study is to present middle-term results of tailored bone and soft-tissue surgeries in subluxated and dislocated hips in children affected by cerebral palsy.

Methods: A total of 87 medical records belonging to 73 children affected by CP, treated with combined soft-tissue releases, VDO, and pelvic osteotomy, were reviewed retrospectively. Radiological measurements of AI, RI, and NSA were obtained before surgery, postoperatively, at 12 and 24 months after surgery.

Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder.

Background: The first year of life is the period of greatest brain plasticity. Postpartum depression can adversely affect the first interactions with the child and, consequently, their emotional, social, and cognitive development.

Objectives: First, to describe the developmental profile of six-month-old infants of mothers suffering from severe postpartum depression, and, second, to compare the development of infants whose mothers suffer from depression with or without bipolar disorder.

Metabolomics-Driven Insights into Biomarkers for Poor Ovarian Response: A Narrative Review.

Poor ovarian response (POR) remains a significant challenge in the field of assisted reproductive technology (ART), as the quantity and quality of oocytes retrieved directly influence embryo implantation, clinical pregnancy, and live birth rates. Metabolomics has become a valuable tool for elucidating the molecular mechanisms underlying diminished ovarian reserve (DOR) and POR. This review aims to synthesize findings from metabolomic studies examining metabolite expression patterns in serum and follicular fluid samples from women with POR.

Impact of First- and Second-Generation Tyrosine Kinase Inhibitors on the Development of Graft-Versus-Host Disease in Individuals with Chronic Myeloid Leukemia: A Retrospective Analysis on Behalf of the Polish Adult Leukemia Group.

: The implementation of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia (CML) has brought a significant improvement in the prognosis for CML patients and a decrease in the number of patients requiring allogeneic hematopoietic stem cell transplantation (allo-HCT). Nevertheless, the impact of TKIs on allo-HCT outcomes has not been thoroughly explored. : The main endpoint of our research was to assess the impact of prior TKI treatment on acute graft-versus-host disease (aGvHD) and chronic graft-versus-host disease (cGvHD).

Dynamic Trends in Aquatic Product Supply and Consumption in China: Implications for Sustainable Diets and Environmental Impact Reduction.

Aquatic foods play a pivotal role in transforming food systems. As the world's leading producer, consumer, and trader of aquatic products, China's potential for sustainable supply and consumption is critical to understand. The aim of this study was to depict the dynamic trends of aquatic products and the consequences of sustainable diets and environmental impacts.

Preparation and characterization of SPE column with smart green molecularly imprinted polymers materials for selective determination of S-metolachlor herbicide.

The presence of traces of herbicides in ground and surface waters can have adverse impacts on humans and the environment. Therefore, developing a highly selective and reusable adsorbent for monitoring water quality has become important. This article describes smart green molecularly imprinted polymers (MIPs) as selective sorbents of S-metolachlor herbicide for solid phase extraction (SPE).

Development of a nasal spray based on cyclodextrin/hydrophobically-modified hydroxypropyl-methyl cellulose for the prevention of viral respiratory infections.

The work aims to develop mucoadhesive and thermo-responsive in situ gelling systems, using hydrophobically-modified hydroxypropyl-methyl cellulose (Sangelose, SG) and beta-cyclodextrin (β-CD) derivatives, for preventing viral respiratory infections. Eight SG/CD systems with varying CD concentrations were evaluated for rheological properties, mucoadhesiveness, spreadability and sprayability via nasal devices; cytotoxicity was in vitro investigated on reconstituted nasal epithelia. Additionally, droplet size distribution and spray deposition were assessed for the most promising systems.

Cropland associated with risk of Parkinson's disease in the northern Great Plains.

Introduction: We sought to identify regional associations between cropland density and crop types and PD in the U.S.

Methods: We conducted a population-based study of 21,639,190 Medicare beneficiaries, 89,790 with incident PD in 2009.

Assessing riparian functioning condition for improved ecosystem services: A case study of the Back Creek watershed (Virginia, USA).

Riparian functioning condition refers to a rating and description of the current ecological status of a reach of a riparian ecosystem in consideration of its potential hydrology, vegetation, and geomorphology. Reach rating options are Proper Functioning Condition (PFC), Functional-At-Risk (FAR), Non-Functional, and apparent or monitored trends. We assessed the functioning condition of flowing riverbank areas of Back Creek located in Virginia (USA) following a PFC protocol developed by the U.

Direct Frequency Comb Cavity Ring-Down Spectroscopy Using Vernier Filtering.

We present direct frequency comb cavity ring-down spectroscopy with Vernier filtering as a straightforward approach to sensitive and multiplexed trace gas detection. The high finesse cavity acts both to extend the interaction length with the sample and as a spectral filter, alleviating the need for dispersive elements or an interferometer. In this demonstration, a free running interband cascade laser was used to generate a comb centered at 3.

Isolation and Total Synthesis of Ukabamide, an Antitrypanosomal Lipopeptide from a Marine sp. Cyanobacterium.

Human African trypanosomiasis (HAT) is one of the most lethal of the neglected tropical diseases. While the discovery of a novel antitrypanosomal drug is highly desired, the creation of a superior lead compound is challenging. Herein we report ukabamide (), which was isolated from a marine sp.

[T-cell large granular lymphocytic leukemia and Felty's syndrome in rheumatoid arthritis].

Neutropenia in rheumatoid arthritis (RA) is a problem that often needs to be addressed. Side effects of basic antirheumatic treatment, infections or substrate deficiencies are common causes; however, T‑cell large granular lymphocytic (T-LGL) leukemia, a mature T‑cell neoplasm, can also lead to autoimmune cytopenia. The T‑LGL leukemia can be associated not only with RA but also with other autoimmune diseases or neoplasms.