3,492 results match your criteria: "Universita di Pavia[Affiliation]"

K^{+}K^{-} pairs may be produced in photonuclear collisions, either from the decays of photoproduced Ï•(1020) mesons or directly as nonresonant K^{+}K^{-} pairs. Measurements of K^{+}K^{-} photoproduction probe the couplings between the Ï•(1020) and charged kaons with photons and nuclear targets. The kaon-proton scattering occurs at energies far above those available elsewhere.

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Higgsinos with masses near the electroweak scale can solve the hierarchy problem and provide a dark matter candidate, while detecting them at the LHC remains challenging if their mass splitting is O(1  GeV). This Letter presents a novel search for nearly mass-degenerate Higgsinos in events with an energetic jet, missing transverse momentum, and a low-momentum track with a significant transverse impact parameter using 140  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV collected by the ATLAS experiment. For the first time since LEP, a range of mass splittings between the lightest charged and neutral Higgsinos from 0.

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Music and social interactions represent two of the most important sources of pleasure in our lives, both engaging the mesolimbic dopaminergic system. However, there is limited understanding regarding whether and how sharing a musical activity in a social context influences and modifies individuals' rewarding experiences. Here, we aimed at (1) modulating the pleasure derived from music under different social scenarios and (2) further investigating its impact on reward-related prosocial behavior and memory.

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Angular correlations between heavy quarks provide a unique probe of the quark-gluon plasma created in ultrarelativistic heavy-ion collisions. Results are presented of a measurement of the azimuthal angle correlations between muons originating from semileptonic decays of heavy quarks produced in 5.02 TeV Pb+Pb and pp collisions at the LHC.

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  • Airway epithelial cells act as a protective barrier against germs and harmful substances and can send signals to boost immune responses when they detect infections.
  • If these cells don’t work well, it can lead to more sickness, so adding probiotics, especially heat-killed bacteria like tyndallized bacteria (TB), is gaining attention for helping with respiratory issues.
  • In a study, TB were found to be safe and helped improve healing and the immune response in airway cells, suggesting they could help prevent and manage respiratory infections better.
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  • Archive tissues are valuable for molecular research but often suffer from degraded biomolecules like proteins, DNA, and RNA.
  • The study compares the effectiveness of nCounter Nanostring technology for quantifying mRNA in Bouin's fixed and paraffin-embedded (BFPE) tissues versus standard formalin-fixed and paraffin-embedded (FFPE) tissues.
  • Results indicate that Nanostring technology is more effective than qPCR and ddPCR methods in detecting target mRNA, yet RNA degradation still limits the accuracy of gene expression conclusions.
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  • Atherosclerosis involves lipid buildup and plaque formation in arteries, significantly driven by oxidative modifications of low-density lipoprotein (ox-LDL).
  • Ox-LDL contributes to inflammation, foam-cell formation, and smooth muscle cell issues, with LOX-1 being a key receptor that exacerbates these effects and promotes plaque development.
  • The relationship between LOX-1 activation and atherosclerosis is complex, and more research is needed to see if targeting LOX-1 could help in preventing or treating atherosclerosis.
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A search for exotic decays of the Higgs boson () with a mass of 125 to a pair of light pseudoscalars is performed in final states where one pseudoscalar decays to two quarks and the other to a pair of muons or leptons. A data sample of proton-proton collisions at corresponding to an integrated luminosity of 138 recorded with the CMS detector is analyzed. No statistically significant excess is observed over the standard model backgrounds.

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  • - This Letter discusses the measurement of ridge yields from charged hadron angular correlations in proton-proton collisions at a high energy of 13 TeV, specifically within certain pseudorapidity and transverse momentum ranges.
  • - The research extends ridge yield measurements to low charged-particle multiplicity regions, where typically a strong interacting medium is not expected to form during collisions.
  • - Findings indicate that ridge yields in pp collisions are significantly higher than those observed in e^{+}e^{-} collisions, suggesting that processes in e^{+}e^{-} annihilations do not significantly influence long-range correlations in proton-proton interactions.
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Copper-containing nitrous oxide reductase catalyzes a 2-electron reduction of the green-house gas NO to yield N. It contains two metal centers, the binuclear electron transfer site Cu, and the unique, tetranuclear Cu center that is the site of substrate binding. Different forms of the enzyme were described previously, representing variations in oxidation state and composition of the metal sites.

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Introduction: Given the significance of healthcare decisions in women with BRCA1 and BRCA2 mutations and their impact on patients' lives, this study aims to map the existing literature on decision regret in women with BRCA1 and BRCA2 mutations.

Methods: A scoping review was conducted in the following databases: PubMed, Embase, Scopus, CINAHL, Cochrane, and Google Scholar. Inclusion criteria focused on decision regret in the female population with BRCA1 and/or BRCA2 mutations, with no restrictions on the methodologies of the included studies, but only in the English language.

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Objective: To summarise current data regarding the use of imaging in crystal-induced arthropathies (CiAs) informing a European Alliance of Associations for Rheumatology task force.

Methods: We performed four systematic searches in Embase, Medline and Central on imaging for diagnosis, monitoring, prediction of disease severity/treatment response, guiding procedures and patient education in gout, calcium pyrophosphate dihydrate deposition (CPPD) and basic calcium phosphate deposition (BCPD). Records were screened, manuscripts reviewed and data of the included studies extracted.

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  • The ALICE detector measured the cross section for incoherent photonuclear production of J/ψ vector mesons, focusing on the Mandelstam |t| variable, during ultraperipheral collisions of Pb nuclei at a very high energy of 5.02 TeV.
  • The measurement was conducted within a rapidity interval of |y|<0.8 and covers a specific range of Bjorken-x values.
  • Analysis showed that models without quantum fluctuations in the gluon density predicted a much steeper |t|-dependence than observed, but including these fluctuations improved the models' alignment with the data.
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Introduction: Incestuous behaviors are often placed in family constellations that are highly dysfunctional from the perspective of communication between members and also with regard to the roles and expectations held in the family. The expert case being presented reflects these characteristics.

Methods: Beginning with an expert case of particular interest with respect to incestuousness and destructibility, the authors report considerations from a clinical criminological and forensic psychological-psychiatric point of view on the link between the two item.

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Objectives: occupational exposure to vapours, gases, dusts and fumes (VGDF) plays an important role in the development and exacerbation of respiratory diseases. The aim of this study is to evaluate the possible association of occupational exposure to airborne pollutants and chronic respiratory diseases.

Design: multicase-control study.

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  • The study evaluated the effectiveness and safety of filgotinib, a medication for rheumatoid arthritis (RA), using data from the Italian GISEA registry.
  • In a cohort of 246 RA patients, significant improvements in disease activity and pain levels were observed after 3 and 12 months of treatment, with retention rates of 84.5% at 6 months and 75.8% at 12 months.
  • Overall, filgotinib was found to be safe and effective, with a higher risk of discontinuation in difficult-to-treat RA patients compared to those who were new to biologic treatment.
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Early seizures and risk of epilepsy and death after intracerebral haemorrhage: The MUCH Italy.

Eur Stroke J

September 2024

Dipartimento di Scienze del Sistema Nervoso e del Comportamento, Unità di Statistica Medica e Genomica, Università di Pavia, Italia.

Introduction: It is unclear which patients with non-traumatic (spontaneous) intracerebral haemorrhage (ICH) are at risk of developing acute symptomatic seizures (provoked seizures occurring within the first week after stroke onset; early seizures, ES) and whether ES predispose to the occurrence of remote symptomatic seizures (unprovoked seizures occurring more than 1 week after stroke; post-stroke epilepsy, PSE) and long-term mortality.

Patients And Methods: In the setting of the Multicenter Study on Cerebral Haemorrhage in Italy (MUCH-Italy) we examined the risk of ES and whether they predict the occurrence of PSE and all-cause mortality in a cohort of patients with first-ever spontaneous ICH and no previous history of epilepsy, consecutively hospitalized in 12 Italian neurological centers from 2002 to 2014.

Results: Among 2570 patients (mean age, 73.

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This Letter presents the first study of Higgs boson production in association with a vector boson (V=W or Z) in the fully hadronic qqbb final state using data recorded by the ATLAS detector at the LHC in proton-proton collisions at sqrt[s]=13  TeV and corresponding to an integrated luminosity of 137  fb^{-1}. The vector bosons and Higgs bosons are each reconstructed as large-radius jets and tagged using jet substructure techniques. Dedicated tagging algorithms exploiting b-tagging properties are used to identify jets consistent with Higgs bosons decaying into bb[over ¯].

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The growing interest in maize landraces over the past two decades has led to the need to characterize the Italian maize germplasm. In Italy, hundreds of maize landraces have been developed, but only a few of them have been genetically characterized, and even fewer are currently employed in agriculture or for breeding purposes. In the present study, 13 maize landraces of the west Emilia-Romagna region were morphologically and genetically characterized.

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The observation of WWγ production in proton-proton collisions at a center-of-mass energy of 13 TeV with an integrated luminosity of 138  fb^{-1} is presented. The observed (expected) significance is 5.6 (5.

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We report the measurement of the helicity asymmetry E for the pπ^{0} and nπ^{+} final states using, for the first time, an elliptically polarized photon beam in combination with a longitudinally polarized target at the Crystal Ball experiment at MAMI. The results agree very well with data that were taken with a circularly polarized photon beam, showing that it is possible to simultaneously measure polarization observables that require linearly (e.g.

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Generalist species, which exploit a wide range of food resources, are expected to be able to combine available resources as to attain their specific macronutrient ratio (percentage of caloric intake of protein, lipids and carbohydrates). Among mammalian predators, the red fox Vulpes vulpes is a widespread, opportunistic forager: its diet has been largely studied, outlining wide variation according to geographic and climatic factors. We aimed to check if, throughout the species' European range, diets vary widely in macronutrient composition or foxes can combine complementary foods to gain the same nutrient intake.

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A search is reported for near-threshold structures in the J/ψJ/ψ invariant mass spectrum produced in proton-proton collisions at sqrt[s]=13  TeV from data collected by the CMS experiment, corresponding to an integrated luminosity of 135  fb^{-1}. Three structures are found, and a model with quantum interference among these structures provides a good description of the data. A new structure is observed with a local significance above 5 standard deviations at a mass of 6638_{-38}^{+43}(stat)_{-31}^{+16}(syst)  MeV.

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Orbital/ocular inflammatory involvement in VEXAS syndrome: Data from the international AIDA network VEXAS registry.

Semin Arthritis Rheum

June 2024

Rheumatology Unit, Policlinico "Le Scotte", Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, viale Bracci 16, Siena 53100, Italy; Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena, Siena, Italy. Electronic address:

Article Synopsis
  • - VEXAS syndrome is a new autoinflammatory disease that often affects various organs, with noticeable inflammatory issues in the eyes and orbits.
  • - In a study of 59 VEXAS patients, 45.8% exhibited orbital/ocular problems, with periorbital edema and episcleritis being the most common conditions observed.
  • - There is a significant link between relapsing polychondritis and eye involvement in VEXAS, and patients with eye issues showed higher mortality rates, indicating the need for closer monitoring by healthcare providers.
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Objectives: An increased number of elderly individuals affected by rheumatoid arthritis (RA) has been reported, including both patients with RA onset in advanced age and patients aged with the disease. In this registry-based study, we aimed to analyze the retention rate and cause of discontinuation of biologic (b) and targeted synthetic (ts)-disease-modifying anti-rheumatic drugs (DMARDs) in RA patients over 65 year old.

Methods: RA patients enrolled in the Italian GISEA registry and starting a b- or a ts-DMARD over 65 years of age were included.

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