Palladium-catalyzed reaction of aryl iodides with acetic anhydride. A carbon monoxide-free synthesis of acetophenones.

[reaction: see text] The palladium-catalyzed reaction of aryl iodides with acetic anhydride provides a straightforward and experimentally simple carbon monoxide-free route to acetophenones. The reaction tolerates a wide range of functionalized aryl iodides. Acetophenones are isolated in excellent yield with a variety of neutral, slightly electron-rich, and slightly electron-poor aryl iodides, whereas moderate yields are obtained with aryl iodides containing strongly electron-withdrawing substituents.

Unsymmetrical diaryl sulfones through palladium-catalyzed coupling of aryl iodides and arenesulfinates.

[reaction: see text] The palladium-catalyzed coupling of aryl iodides and arenesulfinates provides a simple and extremely efficient new route to unsymmetrical diaryl sulfones, usually isolated in high yield. The reaction tolerates a variety of functionalized aryl iodides, including those containing ether, ester, and nitro groups. The best results have been obtained by using Pd(2)(dba)(3), Xantphos, Cs(2)CO(3), and (n)Bu(4)NCl in toluene at 80 degrees C.

A chiral A2 B2 macrocyclic minireceptor with extreme enantioselectivity.

We describe a novel macrocyclic minireceptor that is assembled from a chiral 1,2-diamine and 5-allyloxyisophthalic acid. After immobilization on HPLC silica, the chiral macrocycle preferentially binds the L-enantiomers of simple amino acid derivatives, with enantioselectivities values up to 3.0 kcal/mol.

Olive mill solid residues as heavy metal sorbent material: a preliminary study.

Biosorption of heavy metals is an innovative and alternative technology to remove these pollutants from aqueous solutions using inactive and dead biomasses such as agricultural and industrial wastes, algae and bacteria. In this study olive mill solid residue was used as heavy metal adsorbent material for its wide availability as agricultural waste and also for its cellulosic matrix, rich of potential metal binding active sites. Preliminary studies concerned with the removal of different heavy metals (Hg, Pb, Cu, Zn and Cd), the effect of pre-treatments by water and n-hexane and the regeneration possibility.

[Difficult endoscopic extraction: pneumomediastinum and bilateral pneumothorax after attempted endoscopic extraction of needle incarcerated in hiatal hernia].

From June 1987 to April 2000, 167 (74%) of 223 patients suspected of swallowing foreign bodies were treated. Hundred-sixty-three were successfully treated endoscopically. The surgery rate was 2.

[Non-Hodgkin's lymphoma of the testis. Report of a clinical case and review of the literature].

The Authors report a case of primary non-Hodgkin's lymphoma of the testis. Although lymphoma is a rare neoplasm, it is commonest tumor in the elderly age. Surgical therapy is essential but some times it can be associated to radio-chemotherapy.

[Pica and intestinal occlusion: a clinical case].

Accidental or voluntary foreign bodies ingestion is a frequent reported event in emergency departments. Complication, foreign body shape related are not often observed and, once occurred, just few a cases need an open surgery approach, about 1%. The Authors report the case of a young woman with pica admitted to their Department in an emergency setting for acute intestinal obstruction due to the ingestion of not specified amount of elastics, which required an open surgery operation.

[Clinical-therapeutic features of gynecomastia].

This study reports 36 cases of gynaecomastia surgically treated. The median age was 25-years old (range 14-65 years). In 27 patients (75%) gynaecomastia was bilateral, in the others only one breast was interested.

[Synchronous multiple gastric adenocarcinoma: a clinical case].

The Authors present a case of synchronous double gastric carcinoma in a 75-year-old man. Synchronous multiple gastric carcinoma (SMGC) constitutes 4% to 10% of all gastric cancers. It exhibits several clinicopathological characteristics that differ from those of solitary cancers: SMGC occurs in older people (men more than women); early carcinoma is observed more frequently in SMGC than in solitary cancers; the rate of intestinal type lesions is higher in multiple than in single gastric carcinoma.

Multi-metallic modelling for biosorption of binary systems.

In this paper a specially propagated biomass of Sphaerotilus natans was tested as adsorbent for binary solutions of Cu-Cd, Cu-Pb and Cu--Zn at different equilibrium pH. The experimental results outline the buffering effect of H+ at low pH. which masks the competition among metals.

Salmonella enteritidis pericarditis: case report and review of the literature.

A 65-year-old male patient with primary idiopathic dermatomyositis and on regular immunosuppressive therapy was admitted to our Department for fever and dyspnea. A diagnosis of hemorrhagic Salmonella enteritidis pericarditis was made. Treatment necessitated aggressive medical/surgical supervision.

[Staphylococcus aureus sepsis in hospitalized non neutropenic patients: retrospective clinical and microbiological analysis].

Staphylococcus aureus is one of the leading agents of nosocomial infection among adult patients. The aim of this study was to determine the predisposing factors and secondary complications of Staphylococcus aureus septicemia (SAS) in non neutropenic patients, as well as the predictors of the outcome in non neutropenic patients with SAS. We performed a retrospective study of 56 cases of SAS that occurred from January 1997 through June 2001 in patients hospitalized in medical wards at the Policlinico Umberto I, "La Sapienza" University of Rome; we excluded surgical patients and those admitted to the intensive care unit.

[Chronic intestinal inflammatory diseases].

In the last years the research on the etiopathogenesis of the inflammatory bowel disease (IBD) is focused around immunological aspects. Many authors consider that the intestinal inflammation is due to an inappropriate immunological response to normally present antigens in the gut. Two aspects must to be considered between IBD: Crohn's disease and ulcerative colitis.

Some considerations on the kinetics of pathogenic prions formation.

Literature data, respective to kinetics of infectivities due to prion diseases, have been here reconsidered. The autocatalytic phenomenon of prion replication and the process of advancement of the infection are also considered. A model describing the interconversion from "normal" into "pathogenic" prions, and the subsequent growth of the infection, is proposed.