Early onset of septal FtsK localization allows for efficient DNA segregation in SMC-deleted strains.

Structural maintenance of chromosomes (SMC) are ubiquitously distributed proteins involved in chromosome organization. Deletion of causes severe growth phenotypes in many organisms. Surprisingly, can be deleted in , a member of the phylum, without any apparent growth phenotype.

Intensive care unit acquired weakness and physical rehabilitation in the ICU.

Approximately half of critically ill adults experience intensive care unit acquired weakness (ICUAW). Patients who develop ICUAW may have negative outcomes, including longer duration of mechanical ventilation, greater length of stay, and worse mobility, physical functioning, quality of life, and mortality. Early physical rehabilitation interventions have potential for improving ICUAW; however, randomized trials show inconsistent findings on the efficacy of these interventions.

Non-monotonic Variation of Potential-dependent Surface Diffusion at Electrochemical Interfaces in the Presence of Coadsorbates.

The influence of coadsorbed ions on adsorbate diffusion, an inherent effect at solid-liquid interfaces, was studied for adsorbed sulfur on Ag(100) electrodes in the presence of bromide or iodide. Quantitative in situ high-speed scanning tunnelling microscopy (video-STM) measurements were performed both in the potential regime of the c(2×2) halide adlayer at its saturation coverage and in the regime of a disordered adlayer where the halide coverage increases with potential. These studies reveal a surprising non-monotonic potential dependence of Sad diffusion with an initial increase with halide coverage, followed by a decrease upon halide adlayer ordering into the c(2×2) structure.

A Short Cognitive and Neuropsychiatric Assessment Scale for Progressive Supranuclear Palsy.

Background: Patients with Progressive Supranuclear Palsy (PSP) suffer from several neuropsychological impairments. These mainly affect the frontal lobe and subcortical brain structures. However, a scale for the assessment of cognitive and neuropsychiatric disability in PSP is still missing.

Diagnosis and management of de novo non-specific spinal infections: European Association of Neurosurgical Societies (EANS) Spine Section Delphi consensus recommendations.

Introduction: The management of de novo non-specific spinal infections (spondylodiscitis - SD) remains inconsistent due to varying clinical practices and a lack of high-level evidence, particularly regarding the indications for surgery.

Research Question: This study aims to develop consensus recommendations for the diagnosis and management of SD, addressing diagnostic modalities, surgical indications, and treatment strategies.

Material And Methods: A Delphi process was conducted with 26 experts from the European Association of Neurosurgical Societies (EANS).

Enhancing paediatric and congenital cardiology e-learning postgraduate education: insights from the Association for European Paediatric and Congenital Cardiology directed webinar series.

Objective: A series of webinars covering widespread knowledge on paediatric cardiology and cardiac surgery topics was initiated by Association for European Paediatric and Congenital Cardiology, serving towards preparation for the Association for European Paediatric and Congenital Cardiology certification in paediatric and congenital cardiology. This study investigated the impact of webinars as educational tools for junior paediatric cardiologists in the post-COVID-19 pandemic era.

Materials And Methods: A cross-sectional survey design study using an online survey as a tool for the assessment of trainees.

Supporting rotational grazing systems with virtual fencing: paddock transitions, beef heifer performance, and stress response.

Animal welfare is integral to sustainable livestock production, and pasture access for cattle is known to enhance welfare. Despite positive welfare impacts, high labour requirements hinder the adoption of sustainable grazing practices such as rotational stocking management. Virtual fencing (VF) is an innovative technology for simplified, less laborious grazing management and remote animal monitoring, potentially facilitating the expansion of sustainable livestock production.

What influences the distribution of microplastics in the marine environment? An interdisciplinary study reveals key factors driving microplastic in the North Sea.

Microplastics (MP) are known to be ubiquitous. The pathways and fate of these contaminants in the marine environment are receiving increasing attention, but still knowledge gaps exist. In particular, the link between mass-based MP quantification and oceanographic parameters is often lacking.

Phenolic Compounds and Pharmacological Potential of Extracts for the Treatment of Neurodegenerative Diseases.

The search for neuroprotective compounds in lavender is driven by its traditional use for brain health, with antioxidant activity serving as a key mechanism in reducing oxidative stress and supporting cognitive function. Lavender's potential to protect neurons is based on its calming, anti-stress properties, which increase the brain's resistance to neurodegeneration. Although lavender is not a traditional medicinal plant in Ukraine, it is increasingly recognised for its medicinal properties and is widely cultivated in the country.

A Magnetoelectric Distance Estimation System for Relative Human Motion Tracking.

Clinical motion analysis plays an important role in the diagnosis and treatment of mobility-limiting diseases. Within this assessment, relative (point-to-point) tracking of extremities could benefit from increased accuracy. Given the limitations of current wearable sensor technology, supplementary spatial data such as distance estimates could provide added value.

Performance Responses and Fillet Quality of Rainbow Trout () to Increasing Addition Levels of Dietary Supplementation of Guanidinoacetic Acid.

Guanidinoacetic acid (GAA) plays an important role in cellular energy use and protein synthesis. The objectives of this study were to determine the optimal level of dietary GAA regarding the growth performance and fillet characteristics of rainbow trout (). A total of 300 trout (initial weight, 66.

Silicone Fiducial Markers Improve Precision in Uveal Melanoma Radiation Therapy.

: Accurate target definition, treatment planning and delivery increases local tumor control for radiotherapy by minimizing collateral damage. To achieve this goal for uveal melanoma (UM), tantalum fiducial markers (TFMs) were previously introduced in proton and photon beam radiotherapy. However, TFMs cause pronounced scattering effects in imaging that make the delineation of small tumors difficult.

Association of Corticosteroid Inhaler Type with Saliva Microbiome in Moderate-to-Severe Pediatric Asthma.

: Metered-dose inhalers (MDIs) and dry powder inhalers (DPIs) are common inhaled corticosteroid (ICS) inhaler devices. The difference in formulation and administration technique of these devices may influence oral cavity microbiota composition. We aimed to compare the saliva microbiome in children with moderate-to-severe asthma using ICS via MDIs versus DPIs.

The fundamentals of eye tracking part 2: From research question to operationalization.

In this article, we discuss operationalizations and examples of experimental design in eye-tracking research. First, we distinguish direct operationalization for entities like saccades, which are closely aligned with their original concepts, and indirect operationalization for concepts not directly measurable, such as attention or mind-wandering. The latter relies on selecting a measurable proxy.

AI-based assessment of longitudinal multiple sclerosis MRI: Strengths and weaknesses in clinical practice.

Objectives: In Multiple Sclerosis (MS) cerebral MRI is essential for disease and treatment monitoring. For this purpose, software solutions are available to support the radiologist with image interpretation and reporting of follow up imaging. Aim of this study was to evaluate an AI based software for longitudinal lesion detection with clinical data and to determine the influence of different MRI machines in such setting.

Tire-derived compounds, phthalates, and trace metals in the Kiel Fjord (Germany).

Concerns about pollutants in the environment are increasing, with substances such as plastic additives drawing particular concern due to their potential harmful effects on organisms. This study investigates current levels of several contaminants in the Kiel Fjord. Some pose serious health risks to aquatic life.

Physical climate risk: Stock price reactions to the historically most extreme European and United States heat waves since 1979.

Climate change has heightened the need to understand physical climate risks, such as the increasing frequency and severity of heat waves, for informed financial decision-making. This study investigates the financial implications of extreme heat waves on stock returns in Europe and the United States. Accordingly, the study combines meteorological and stock market data by integrating methodologies from both climate science and finance.

Predictors of prolonged hospital stay of pelvic ring and acetabular fractures - a retrospective analysis in a 10-year period of a level 1 trauma center.

Background: Pelvic ring and acetabular fractures are among the most complicated and severe injury patterns in orthopaedic trauma surgery. Inpatient treatment is not only costly but also very time-consuming. The aim of this study is to identify predictors leading to a prolonged length of hospital stay.

Investigating Past, Present, and Future Trends on Interface Between Marine and Medical Research and Development: A Bibliometric Review.

The convergence of marine sciences and medical studies has the potential for substantial advances in healthcare. This study uses bibliometric and topic modeling studies to map the progression of research themes from 2000 to 2023, with an emphasis on the interdisciplinary subject of marine and medical sciences. Building on the global publication output at the interface between marine and medical sciences and using the Hierarchical Dirichlet Process, we discovered dominating research topics during three periods, emphasizing shifts in research focus and development trends.

Advances in Biomimetics: The Power of Diversity.

Biomimetics research on living systems attempts to transfer their properties and functions to engineering applications [...

Peri-Implant Soft Tissue in Contact with Zirconium/Titanium Abutments from Histological and Biological Perspectives: A Concise Review.

Dental implants are crucial in contemporary oral rehabilitation, necessitating optimal integration with the surrounding soft tissues for durable success. The attachment between the implant surface and peri-implant mucosa should establish a secure seal to prevent bacterial infiltration and subsequent tissue inflammation. This concise review examines the histological and biological perspectives of peri-implant soft tissue reactions to zirconium and titanium abutments, shedding light on their respective advantages and limitations.