Non-Projective Two-Weight Codes.

It has been known since the 1970's that the difference of the non-zero weights of a projective Fq-linear two-weight code has to be a power of the characteristic of the underlying field. Here, we study non-projective two-weight codes and, e.g.

Dual-Site Model for Calculations of Gibbs Free Energies and Enthalpies of Adsorption: Methane in Zeolite Mobile Five (H-MFI).

Quantum chemical hybrid MP2:PBE+D2 calculations in combination with molecular statistics are employed to calculate enthalpies and Gibbs free energies of adsorption for CH at Brønsted acid sites [bridging Si-O(H)-Al groups] and silica wall sites (Si-O-Si) of the proton form of zeolite MFI (H-ZSM-5) and its purely siliceous analogue Silicalite-1. A Langmuir model is adopted to calculate the amounts of CH adsorbed at each type of site from the Gibbs free energies. The combination of these results according to the ratio of silica wall sites and Brønsted acid sites in the sample yields adsorption isotherms for zeolites with different Si/Al ratios.

H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasion.

Histone variants play a crucial role in chromatin structure organization and gene expression. Trypanosomatids have an unusual H2B variant (H2B.V) that is known to dimerize with the variant H2A.

Cost and survival of video-assisted thoracoscopic lobectomy versus open lobectomy in lung cancer patients: a propensity score-matched study.

Objectives: A video-assisted thoracoscopic surgery (VATS) is an accepted alternative to open thoracotomy (OT) in lung cancer patients undergoing lobectomy, but evidence of the benefits of VATS remains inconsistent. The aim of this study was to compare VATS and OT regarding survival, costs and length of hospital stay (LOS).

Methods: We identified lung cancer patients (incident 2013) undergoing VATS or OT from German insurance claims data and performed 1:2 propensity score matching.

Penetrating Foreign Bodies in Head and Neck Trauma: A Surgical Challenge.

Penetrating foreign bodies of different origins in the head and neck are rare and potentially dangerous injuries, which might pose problems for their detection, primary care, and final treatment. Depending on the severity of the underlying trauma, some injuries present a higher risk for the presence of foreign bodies. Minor wounds, including common lacerations, are likely to be contaminated with loose gravel debris or dental fragments, and need to be distinguished from severe wounds caused by impalement, shootings, stabbings, and explosions.

SuperDRUG2: a one stop resource for approved/marketed drugs.

Regular monitoring of drug regulatory agency web sites and similar resources for information on new drug approvals and changes to legal status of marketed drugs is impractical. It requires navigation through several resources to find complete information about a drug as none of the publicly accessible drug databases provide all features essential to complement in silico drug discovery. Here, we propose SuperDRUG2 (http://cheminfo.

Prospects for Observing and Localizing Gravitational-Wave Transients with Advanced LIGO and Advanced Virgo.

We present a possible observing scenario for the Advanced LIGO and Advanced Virgo gravitational-wave detectors over the next decade, with the intention of providing information to the astronomy community to facilitate planning for multi-messenger astronomy with gravitational waves. We determine the expected sensitivity of the network to transient gravitational-wave signals, and study the capability of the network to determine the sky location of the source. We report our findings for gravitational-wave transients, with particular focus on gravitational-wave signals from the inspiral of binary neutron-star systems, which are considered the most promising for multi-messenger astronomy.

Fruit and vegetables consumption is associated with higher vitamin intake and blood vitamin status among European adolescents.

Background/objectives: Current research in adults indicates that fruit and vegetable (FAV) consumption increases serum levels of vitamins C, E and folate of β-carotene and reduces homocysteine concentrations. The aim of the present study was to examine the association of FAV consumption on vitamin intakes and their impact on blood vitamin concentrations in European adolescents.

Subject/methods: This multi-center cross-sectional study included 702 (53.

Whole exome sequencing links dental tumor to an autosomal-dominant mutation in ANO5 gene associated with gnathodiaphyseal dysplasia and muscle dystrophies.

Tumors of the jaws may represent different human disorders and frequently associate with pathologic bone fractures. In this report, we analyzed two affected siblings from a family of Russian origin, with a history of dental tumors of the jaws, in correspondence to original clinical diagnosis of cementoma consistent with gigantiform cementoma (GC, OMIM: 137575). Whole exome sequencing revealed the heterozygous missense mutation c.

Expression of inhibitory receptors on intratumoral T cells modulates the activity of a T cell-bispecific antibody targeting folate receptor.

T-cell bispecific antibodies (TCBs) are a novel therapeutic tool designed to selectively recruit T-cells to tumor cells and simultaneously activate them. However, it is currently unknown whether the dysfunctional state of T-cells, embedded into the tumor microenvironment, imprints on the therapeutic activity of TCBs. We performed a comprehensive analysis of activation and effector functions of tumor-infiltrating T-cells (TILs) in different tumor types, upon stimulation by a TCB targeting folate receptor 1 and CD3 (FolR1-TCB).

Photodissociation at various wavelengths: fragmentation studies of oxazine 170 using nanosecond laser pulses.

The fragmentation of oxazine 170, a rhodamine-type dye, has been investigated by means of collisions and photodissociation with visible and ultraviolet radiation in a Fourier transform ion cyclotron resonance mass spectrometer. Because of an improved experimental setup, the photodissociation processes of stored ions are measured with high intensity with respect to the absorbed photons. By isotope labelling and quantum chemical calculations, the various fragmentation mechanisms are investigated.

Supramolecular complex coupled to a metal nanoparticle: computational studies on the optical absorption.

Absorption spectra of a supramolecular complex (SC) placed in the proximity of a spherical metal nanoparticle (MNP) are computed. A description of the absorption is used that is based on a density matrix propagation. The applied density matrix theory starts from a microscopic model including the Coulomb interaction between the SC and the MNP.

One electron organozinc ligands in metal rich molecules by Ga/Zn exchange: from Cp*Rh(GaCp*)2 to Cp*Rh(ZnR)4 units.

Two unusual compounds, [{Cp*Rh(ZnCp*)(2)(ZnMe)(ZnCl)}(2)] (1) and [Cp*(2)Rh][(Cp*Rh)(6)Zn(18)Cl(12)(mu(6)-Cl)] (2), both bearing closed shell 18-electron square pyramidal Cp*RhZn(4) building units were obtained by combined Ga/Zn, Me/Cp* and Me/Cl exchange upon treatment of [Cp*Rh(GaCp*)(2)(GaCl(2)Cp*)] with ZnMe(2) (Cp* = pentamethylcyclopentadienyl).

Coherence effects in digital in-line holographic microscopy.

We analyze the effects of partial coherence in the image formation of a digital in-line holographic microscope (DIHM). The impulse response is described as a function of cross-spectral density of the light used in the space-frequency domain. Numerical simulation based on the applied model shows that a reduction in coherence of light leads to broadening of the impulse response.

How writing system and age influence spatial representations of actions: a developmental, cross-linguistic study.

Recently, researchers reported a bias for placing agents predominantly on the left side of pictures. Both hemispheric specialization and cultural preferences have been hypothesized to be the origin of this bias. To evaluate these hypotheses, we conducted a study with participants exposed to different reading and writing systems: Germans, who use a left-to-right system, and Israelis, who use a right-to-left system.

Targeted gene deletion in Candida albicans wild-type strains by MPAR flipping.

Many genetic and phenotypic changes occur during the development of drug resistance in fungi. A straightforward approach to assess the contribution of a specific gene to drug resistance is to examine its inactivation in a resistant isolate and to analyze the effect of the mutation on the resistance phenotype. The generation of knockout mutants in the diploid yeast Candida albicans requires two rounds of gene replacement to inactivate both alleles of a target gene.

CARE-2 fingerprinting of Candida albicans isolates.

The emergence of resistance to antifungal drugs in medically important fungi has become a significant problem in recent years. Probably the best-studied example is the development of resistance to the widely used antifungal agent fluconazole in the yeast Candida albicans. The availability of matched series of clinical isolates representing the same strain in which drug resistance developed over time has provided opportunities to detect cellular alterations that are correlated with drug resistance.

Nuclear trafficking of La protein depends on a newly identified nucleolar localization signal and the ability to bind RNA.

Here we provide evidence for an interaction-dependent subnuclear trafficking of the human La (hLa) protein, known as transient interaction partner of a variety of RNAs. Among these, precursor transcripts of certain RNAs are located in the nucleoplasm or nucleolus. Here we examined which functional domains of hLa are involved in its nuclear trafficking.