Nano-Based Drug Delivery Systems of Potent MmpL3 Inhibitors for Tuberculosis Treatment.

Tuberculosis remains one of the world's deadliest infectious diseases, accounting for nearly 1.3 million deaths every year. Tuberculosis treatment is challenging because of the toxicity, decreased bioavailability at the target site of the conventional drugs and, most importantly, low adherence of patients; this leads to drug resistance.

Maria Montessori: A complex and multifaceted historiographical subject.

The main goal of this essay is to outline the historiographical profile of Maria Montessori (1870 -1952), which has been subject to substantial investigation in recent years (Babini & Lama, 2000; De Giorgi, 2013; Foschi, 2012; Giovetti, 2009; Marazzi, 2000). These latest analyses have highlighted a previously unacknowledged complexity. The historiographical literature on Maria Montessori, her pedagogical method, and her experiences in different parts of the world is composed of numerous contributions characterized by different focuses and purposes.

Higher-order corrections to the effective potential close to the jamming transition in the perceptron model.

In view of the results achieved in a previously related work [A. Altieri, S. Franz, and G.

Tailoring chiro-optical effects by helical nanowire arrangement.

In this work, we experimentally investigate the chiro-optical properties of 3D metallic helical systems at optical frequencies. Both single and triple-nanowire geometries have been studied. In particular, we found that in single-helical nanostructures, the enhancement of chiro-optical effects achievable by geometrical design is limited, especially with respect to the operation wavelength and the circular polarization conversion purity.