1,823 results match your criteria: "Universit&tsstr. 1[Affiliation]"

Background: Brain drain refers to the migration of qualified professionals to developed countries in search of better living and working conditions, and has become a global concern, particularly in the healthcare sector. Migration of highly skilled nurses results in increased workload for the remaining nursing staff, limited access to quality healthcare services, and contributes to disparities in healthcare. Therefore, nursing students represent a critical demographic group for understanding the drivers of brain drain in the healthcare sector.

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Background And Objectives: Brain tumors are complex diseases that require careful diagnosis and treatment. A minor error in the diagnosis may easily lead to significant consequences. Thus, one must place a premium on accurately identifying brain tumors.

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Ten novel Gram-negative, aerobic, non-sporulating, yellow-pigmented rod-shaped bacterial strains motile by gliding were isolated from marine organisms/environments in French Polynesia. Three of them designated as 190524A05c, 190524A02b and 190130A14a were retrieved from orbicular batfish () mucus. Online database comparisons using 16S rRNA amplicons resulted in over 95% similarity to the genus .

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In this study, we report the synthesis and photocatalytic performance of Co₃O₄-decorated hexagonal boron nitride (hBN) composites for degrading methylene blue (MB) and ibuprofen (IBF) under sunlight irradiation. Using a dry impregnation method, the composites were prepared with varying Co₃O₄ loadings (0.5%, 1%, 2%).

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Understanding Parkinson's: The microbiome and machine learning approach.

Maturitas

December 2024

Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Universiteitsweg 99, Utrecht 3508 TB, the Netherlands.

Objective: Given that Parkinson's disease is a progressive disorder, with symptoms that worsen over time, our goal is to enhance the diagnosis of Parkinson's disease by utilizing machine learning techniques and microbiome analysis. The primary objective is to identify specific microbiome signatures that can reproducibly differentiate patients with Parkinson's disease from healthy controls.

Methods: We used four Parkinson-related datasets from the NCBI repository, focusing on stool samples.

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The association between acute transverse myelitis and COVID-19 vaccination in Korea: Self-controlled case series study.

Eur J Neurol

January 2025

Department of Health Convergence, College of Science and Industry Convergence, Ewha Womans University, Seoul, Republic of Korea.

Background: Acute transverse myelitis (ATM) has been reported as a potential association between COVID-19 vaccination. In this study, we aimed to investigate the association between the COVID-19 vaccination and ATM.

Methods: A self-controlled case series study was performed using a large database that combine the COVID-19 vaccine registry and the national claims database.

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Integrate-and-fire models are an important class of phenomenological neuronal models that are frequently used in computational studies of single neural activity, population activity, and recurrent neural networks. If these models are used to understand and interpret electrophysiological data, it is important to reliably estimate the values of the model's parameters. However, there are no standard methods for the parameter estimation of Integrate-and-fire models.

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In this study, we develop a comprehensive model to investigate the intricate relationship between the bone remodeling process, tumor growth, and bone diseases such as multiple myeloma. By analyzing different scenarios within the Basic Multicellular Unit, we uncover the dynamic interplay between remodeling and tumor progression. The model developed developed in the paper are based on the well accepted Komarova's and Ayati's models for the bone remodeling process, then these models were modified to include the effects of the tumor growth.

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Interplay Between Spinmerism and Spin-Orbit Coupling for a d2 Metal Ion in an Open-Shell Ligand Field.

Chemphyschem

December 2024

Laboratoire de Chimie Quantique, Universit� de Strasbourg, Department of Chemistry, 4 rue Blaise Pascal, 67000, Strasbourg, FRANCE.

Recent, theoretical studies have shown that placing a spin-crossover ion in a field of radical ligands can induce local superpositions of local spin states (see Ref.[1,2]). This phenomenon, termed spinmerism, raises questions about its stability when spin-orbit coupling is included.

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Given the significance of investigating ovarian reserve in infertile women, the limitations of existing diagnostic tests, and the absence of similar studies in this area, the present study aimed to examine the relationship between systemic inflammatory markers in patients with diminished ovarian reserve referred to the fertility clinic of Alzahra Hospital in Rasht in the year 2023. This cross-sectional analytical study was conducted on 174 patients referred to the Alzahra Hospital fertility clinic in Rasht. Patients were divided into two categories based on their serum levels of anti-Müllerian hormone (AMH):AMH >1.

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Effectiveness and Safety of the TRIO Optimal Health Management Program in Patients with Type 2 Diabetes Mellitus (T2DM) Initiating Basal Insulin Therapy: Real-World Study.

J Med Internet Res

December 2024

Department of Endocrinology, Endocrine and Metabolic Disease Medical Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, No.321 Zhongshan Road, Nanjing, CN.

Background: Diabetes, a chronic disease necessitating long-term treatment and self-management, presents significant challenges for patients who spend most of their treatment time outside of hospitals. The potential of digital therapeutics for diabetes has garnered recognition from different organizations. Although some prior studies have demonstrated successful reductions in patients' blood glucose levels and body weight through digital diabetes programs, many studies were limited by including prediabetes patients, patients treated with mostly premixed insulin, or evaluating user engagement outcomes rather than clinical outcomes.

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This study investigates the ethanol gas-sensing mechanisms of ZnO nanocrystals with distinct morphologies, synthesized via a hydrothermal method using various alkali sources. Significant differences in the gas-sensing performance and morphology of ZnO samples synthesized with ammonium carbonate (NaCO), hexamethylenetetramine (HMTA), ammonia solution (NH·HO), and sodium hydroxide (NaOH) were observed. ZnO were confirmed to be impurity-free through XRD analysis, and their morphological features were characterized by SEM.

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Electrical polarization switching of perovskite polariton laser.

Nanophotonics

June 2024

Faculty of Physics, Institute of Experimental Physics, University of Warsaw, ul. Pasteura 5, PL-02-093 Warsaw, Poland.

Optoelectronic and spinoptronic technologies benefit from flexible and tunable coherent light sources combining the best properties of nano- and material-engineering to achieve favorable properties such as chiral lasing and low threshold nonlinearities. In this work we demonstrate an electrically wavelength- and polarization-tunable room temperature polariton laser due to emerging photonic spin-orbit coupling. For this purpose, we design an optical cavity filled with both birefringent nematic liquid crystal and an inorganic perovskite.

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The role of evolving niche choice in herbivore adaptation to host plants.

J Evol Biol

December 2024

Department of Theoretical Biology, Faculty of Biology, Bielefeld University, Universit ätsstraÿe 25, 33615 Bielefeld, Germany.

Article Synopsis
  • Individuals in diverse environments often select microenvironments that enhance their fitness, which can lead to quicker adaptation and greater genetic diversity.
  • The study explores how niche choice and evolution influence the development of insecticide resistance in plant-eating insects using an individual-based model.
  • Findings indicate that targeted oviposition (egg-laying) behavior slows down the evolution of resistance compared to random egg placement, promoting the coexistence of different insect types and suggesting that genetic factors also play a significant role.
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A model-based quantification of nonlinear expiratory resistance in Plethysmographic data of COPD patients.

Comput Methods Programs Biomed

November 2024

Department of Mechanical Engineering, Centre for Bio-Engineering, University of Canterbury, Christchurch, New Zealand. Electronic address:

Article Synopsis
  • COPD (Chronic Obstructive Pulmonary Disease) causes increased airway resistance, with severe cases exhibiting expiratory flow limitation (EFL), which traditional linear models fail to accurately represent.
  • A study analyzed plethysmographic data from 100 participants (40 healthy and 60 with COPD) using both linear and nonlinear models to assess expiratory resistance, finding that nonlinear models better captured the complexities of COPD dynamics.
  • Results indicated that airway resistance is significantly higher in COPD patients, particularly in those with EFL, showcasing the ability of nonlinear models to differentiate between severity levels of the disease.
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Article Synopsis
  • Measuring deeply virtual Compton scattering (DVCS) on the neutron is essential for understanding the nucleon's structure through generalized parton distributions (GPDs).
  • Neutron targets help complement data obtained from polarized protons, particularly in determining the poorly understood GPD E, which is crucial for analyzing quark contributions to nucleon spin.
  • The experiment utilized a longitudinally polarized electron beam at Jefferson Lab and the CLAS12 detector to measure DVCS on the neutron for the first time, providing new insights into quark-flavor separation of relevant Compton form factors.
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Objective: The objective of the present study was to develop a method for sampling and detecting an adenovirus-derived gene therapy (GT) vector on isolator worksurfaces.

Methods: We used a quantitative PCR (q-PCR) to detect the viral genome in standard dilutions of pure GT product and extracts of sampled surfaces. We compared three devices for surface sampling (a cotton compress, a cotton swab and a polyester flocked swab) and performed positive control, negative control and induced contamination tests for each.

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Article Title And Bibliographic Information: Bourouni S, Dritsas K, Kloukos D, Wierichs RJ. Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a systematic review and meta-analysis. Clin Oral Investig.

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Metal-organic frameworks (MOFs) form a unique platform for operation with data using ReRAM technology. Here we report on a large-scale fabrication of a MOF-based ReRAM array with 6 × 6 cells, demonstrating 50% variation in their electronic parameters. Despite this inhomogeneity, such a "non-ideal" ReRAM array is used for recording binary information followed by deep learning processes to achieve 95% accuracy of reading.

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This study aimed to evaluate the effects of rumen-protected Met on lactation performance, inflammation, and immune response, and liver glutathione of lactating dairy cows during a subclinical mastitis challenge (SMC). Thirty-two Holstein cows (145 ± 51 DIM) were enrolled in a randomized complete block design. At -21 d relative to the SMC, cows were assigned to dietary treatments, and data were collected before and during the SMC.

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Supplementation with nicotinamide limits accelerated aging in affected individuals with cockayne syndrome and restores antioxidant defenses.

Aging (Albany NY)

November 2024

Laboratory of Biomedical Genomics and Oncogenetics, LR16IPT05, Institut Pasteur de Tunis, Université Tunis El Manar, El Manar I, Tunis 1002, Tunisia.

Cockayne syndrome (CS) is a segmental progeroid syndrome characterized by defects in the DNA excision repair pathway, predisposing to neurodegenerative manifestations. It is a rare genetic disorder and an interesting model for studying premature aging. Oxidative stress and autophagy play an important role in the aging process.

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Article Synopsis
  • Blood-brain barrier disruption in acute ischemic stroke is linked to complications, with GLOS indicating issues in the blood-ocular barrier.
  • In a study of WAKE-UP trial patients, 29% showed GLOS, significantly more than the 7% with HARM.
  • GLOS presence was associated with factors like age, renal function, and white matter hyperintensity but did not correlate with hemorrhagic transformation or functional outcomes.
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Background: Identifying a foreign body aspiration (FBA) still remains a diagnostic difficulty. Moreover, the indications for bronchoscopy in subjects of suspected foreign bodies are not clear. The aim of this study was to evaluate the effectiveness of pediatric pulmonologists in diagnosing FBA.

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