Spatial reorientation in large and small enclosures: comparative and developmental perspectives.

Several vertebrate species, including humans, following passive spatial disorientation appear to be able to reorient themselves by making use of the geometric shape of the environment (i.e., metric properties of surfaces and directional sense).

Different responses to rivastigmine in subcortical vascular dementia and multi-infarct dementia.

Vascular dementia (VaD) is associated with a large amount of heterogeneity, as it groups together a broad category of patients in whom various manifestations of cognitive decline are attributed to cerebrovascular or cardiovascular disease. Thus, a study was designed to determine the effects of rivastigmine on cognitive function, global daily living performance, and behavioral disorders in VaD patients versus an active control (nimodipine), stratifying patients according to the type of VaD, subcortical vascular dementia (sVAD), and multi-infarct dementia (MID). The trial was a prospective study.

Visually guided pointing, the Müller-Lyer illusion, and the functional interpretation of the dorsal-ventral split: conclusions from 33 independent studies.

Models of the human vision propose a division of labor between vision-for-action (identified with the V1-PPT dorsal stream) and vision-for-perception (the V1-IT ventral stream). The idea has been successful in explaining a host of neuropsychological and behavioral data, but has remained controversial in predicting that visually guided actions should be immune from visual illusions. Here we evaluate this prediction by reanalyzing 33 independent studies of rapid pointing involving the Müller-Lyer or related illusions.

Transport and dispersion of particulate Hg associated with a river plume in coastal Northern Adriatic environments.

The role of suspended particulate matter (SPM) as an important carrier of mercury (Hg) dispersed into the Gulf of Trieste and in the adjacent Grado lagoon (Northern Adriatic Sea) was studied during a high Isonzo River inflow and the resulting river plume formation. Despite the fact that extreme flood events are rare during the year, they account for most of the PHg influx (37-112 ngL(-1)) into the Gulf of Trieste. When the river plume is diverted to the SW under the influence of an E-NE wind, the tidal flux acts as a "transport belt" carrying the PHg, mostly inorganic, into the Grado lagoon.

Genetics and mathematics: evidence from Prader-Willi syndrome.

Mathematical abilities were tested in people with Prader-Willi syndrome (PWS), using a series of basic mathematical tasks for which normative data are available. The difference between the deletion and the disomy variants of this condition was explored. While a wide phenotypic variation was found, some basic findings emerge clearly.

Is there an innate geometric module? Effects of experience with angular geometric cues on spatial re-orientation based on the shape of the environment.

Non-human animals and human children can make use of the geometric shape of an environment for spatial reorientation and in some circumstances reliance on purely geometric information (metric properties of surfaces and sense) can overcome the use of local featural cues. Little is known as to whether the use of geometric information is in some way reliant on past experience or, as would likely be argued by advocates of the notion of a geometric module, it is innate. We tested the navigational abilities of newborn domestic chicks reared in either rectangular or circular cages.

Supercritical antisolvent precipitation of nimesulide: preliminary experiments.

The purpose of this preliminary study was to investigate the physico-chemical properties of nimesulide precipitated by continuous supercritical antisolvent (SAS) from different organic solvents like acetone, chloroform and dichloromethane at 40 degrees C and 80, 85 and 88 bar, respectively. Scanning electron microscopy, differential scanning calorimetry, X-Ray diffractometry and in vitro dissolution tests were employed to study how the technological process and the solvent nature would affect the final product. SAS-processed nimesulide particles showed dramatic morphological change in crystalline structure if compared to native nimesulide, resulting in needle and thin rods shaped crystals.

Does violence affect one gender more than the other? The mental health impact of violence among male and female university students.

The impact of violence on health has been studied mostly among women. While the studies including men show that violence is detrimental for them also, knowledge concerning gender differences is scarce. This study explores whether violence has a different impact on males and females in a sample of 502 Italian university students, responding to a self-administered questionnaire.

Chemoenzymatic synthesis and antimicrobial activity evaluation of monogalactosyl diglycerides.

Monogalactosyl diglycerides with medium to long fatty acid acyl chains, were prepared and examined for antimicrobial activity against Gram positive, Gram negative bacteria and fungi. The study of their in vitro antimicrobial activity confirms the significant activity of some monogalactosyl diacylglycerol analogues and establishes for the galactose series that the 1,2-disubstitution and the octanoyl chain are the proper structural features for the maximum activity.

Spin-orbit relativistic calculations of the core excitation spectra of SO2.

The time dependent density functional theory approach within the two-component zero-order relativistic approximation has been applied to the calculation of the core excitation spectra of SO2 molecule. The results obtained reproduce correctly the high resolution experimental spectra and allow the assignment of the spectral features both of the valence and Rydberg regions in the S 1s and O 1s spectra. For the S 2p threshold a correct description of the spin-orbit coupling as well as of the molecular field splitting appears mandatory for a reliable description of the spectrum and a detailed attribution of the complex Rydberg manifold of core excited states.

Rivastigmine and Parkinson dementia complex.

Patients suffering from Parkinson's disease dementia (PDD) have a movement disorder, but it can be difficult to determine whether the functional impairment, which is critical in making the assessment of whether a patient has achieved the threshold for a diagnosis of dementia, is due to the dementia or the underlying Parkinson's disease. Although the cognitive impairment found in nondemented patients with Parkinson's disease is very dysexecutive in nature, the DSM IV (Diagnostic and Statistical Manual of Mental Disorders of the American Psychiatric Association IV) diagnosis of PDD has memory impairment as the defining characteristic of PDD. Severe deficits in cortical, cholinergic, excitatory, neuromodulatory input mean that memory impairment is not always due to encoding and retrieval strategy deficits, but it may also be amnesic without being related to concomitant Alzheimer's disease pathology.

Perception of visual inclination in a real and simulated urban environment.

The perceived inclination of slopes is generally overestimated. We claim that overestimation depends on the use of impoverished stimuli and on the distance between the observer and an inclined surface. In experiment 1, participants reported the perceived inclination of a set of urban roads from two different viewing distances.

A case of malignant mesothelioma in a rice-starch factory.

Introduction: Recent reports of cases of malignant mesothelioma (MM) in "non-traditional" areas of employment are an indication of the numerous occasions in which exposure to asbestos has occurred in the workplace. We describe an unusual case of occupational exposure to asbestos to stress the importance of careful history taking when assessing a patient's work history, especially in generic occupations in which there is apparently no exposure to asbestos.

Case Report: Malignant mesothelioma was diagnosed in a woman worker employed in a factory making rice starch.

Chemoenzymatic synthesis and in vitro studies on the hydrolysis of antimicrobial monoglycosyl diglycerides by pancreatic lipase.

Monoglucosyl and monogalactosyl diglycerides (MGDGs) with medium-long length acyl chains, identified as active components in Euphorbiaceae, were synthesized. They were examined for antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. MGDGs with two octanoyl groups at both 1- and 2-positions showed the most potent activity.

A comparison between two moss species used as transplants for airborne trace element biomonitoring in NE Italy.

Transplants of the mosses Hypnum cupressiforme and Pseudoscleropodium purum used as active biomonitors of airborne trace elements were compared in a survey carried out at Trieste (NE Italy). Twelve elements were considered: Al, As, Cd, Cr, Cu, Fe, Hg, Mn, Pb, Ti, V, Zn. Water-washed materials of H.

The special theory of Brownian relativity: equivalence principle for dynamic and static random paths and uncertainty relation for diffusion.

The theoretical basis of a recent theory of Brownian relativity for polymer solutions is deepened and reexamined. After the problem of relative diffusion in polymer solutions is addressed, its two postulates are formulated in all generality. The former builds a statistical equivalence between (uncorrelated) timelike and shapelike reference frames, that is, among dynamical trajectories of liquid molecules and static configurations of polymer chains.

The role of granulocytes following intravesical BCG prophylaxis.

Objectives: The antitumour effect of bacillus Calmette-Guérin (BCG) still remains relatively undefined. Most investigations on its mechanism of action have focused on mononuclear cells; little consideration has been given to granulocytes. We analysed urine of patients with bladder cancer during 8 wk of intravesical BCG prophylaxis.

Analysis of bioclimatic time series and their neural network-based classification to characterise drought risk patterns in South Italy.

A new approach to characterise geographical areas with a drought risk index (DRI) is suggested, by applying an artificial neural network (ANN) classifier to bioclimatic time series for which operational temporal units (OtUs) are defined. A climatic database, corresponding to a grid of 8 km x 8 km cells covering the Italian peninsula, was considered. Each cell is described by the time series of seven variables recorded from 1989 to 2000.

Spatial reorientation: the effects of space size on the encoding of landmark and geometry information.

The effects of the size of the environment on animals' spatial reorientation was investigated. Domestic chicks were trained to find food in a corner of either a small or a large rectangular enclosure. A distinctive panel was located at each of the four corners of the enclosures.

Retrieval pathways for common and proper names.

Paradigmatic cases of proper name anomia and proper name selective sparing are reviewed from relevant neuropsychological literature. Available evidence supports the existence of functionally and anatomically distinct retrieval pathways for the categories of proper and common names. An information processing model whose main feature lies in the relative independence within the semantic-conceptual system of information concerning individual entities may account for most of the observed phenomena.

Cardiac metastases.

Tumours metastatic to the heart (cardiac metastases) are among the least known and highly debated issues in oncology, and few systematic studies are devoted to this topic. Although primary cardiac tumours are extremely uncommon (various postmortem studies report rates between 0.001% and 0.

Chemoenzymatic synthesis and antimicrobial activity evaluation of monoglucosyl diglycerides.

Monoglucosyl diglycerides with medium-long length fatty acid acyl chains were prepared and examined for antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. The study of their in vitro antimicrobial activity confirms the significant activity of some monoglucosyl diacylglycerol analogues and establishes for the glucose series that the 1,2-disubstitution and the octanoyl chain are the proper structural features for the maximum activity.

Peripheral neuropathy in hepatitis C virus-related mixed cryoglobulinaemia: existing treatments and a positive symptomatic response to oxcarbazepine.

Peripheral neuropathy is the most common symptom in patients with hepatitis C virus (HCV) associated mixed cryoglobulinaemia, in whom it may be the first clinical manifestation. Very frequently, the medical therapy proposed to treat HCV and cryoglobulinaemia causes an exacerbation of the disabling neuropathy. Therefore, other neuropathy treatments have been proposed, such as alternative immunosuppressive agents (steroids or cyclosporine) and plasma exchange, which, according to case reports, have yielded inconsistent results and presumably exert only temporary effects as they do not promote clearance of HCV.

Is math lateralised on the same side as language? Right hemisphere aphasia and mathematical abilities.

The main purpose of the present study was to learn how mathematical abilities are located and develop in the brain with respect to language. Mathematical abilities were assessed in six right-handed patients affected by aphasia following a lesion to their non-dominant hemisphere (crossed aphasia) and in two left-handed aphasics with a right-sided lesion. Acalculia, although in different degrees, was found in all cases.