2,044 results match your criteria: "Univ. Brest[Affiliation]"
Sci Total Environ
September 2024
UMR DECOD Ecosystem Dynamics and Sustainability, Institut Agro, Inrae, Ifremer, 35000 Rennes, France.
The development of an ecosystem approach to fisheries management makes the assessment of the sustainability performance of fisheries a priority. This study examines European tropical tuna purse seine fleets as a case study, employing a multidisciplinary dashboard approach to evaluate historical and current sustainability performances. The aim is to enhance comprehension of the interconnected dimensions of sustainability and pinpoint management policy priorities.
View Article and Find Full Text PDFNat Commun
June 2024
Oceanic Fisheries Programme, The Pacific Community, BP D5 98848, Noumea, New Caledonia.
Environ Toxicol Pharmacol
August 2024
Univ. Brest, INRAE, Laboratoire Universitaire de Biodiversité et Ecologie Microbienne, Plouzané F-29280, France. Electronic address:
Among cereal contaminants, mycotoxins are of concern due to their importance in terms of food and feed safety. The difficulty in establishing a diagnosis for mycotoxicosis relies on the fact that the effects are most often subclinical for chronic exposure and the most common scenario is multi-contamination by various toxins. Mycotoxin co-occurrence is a major food safety concern as additive or even synergic toxic impacts may occur, but also regarding current regulations as they mainly concern individual mycotoxin levels in specific foods and feed in the food chain.
View Article and Find Full Text PDFFood Microbiol
September 2024
Univ Brest, INRAE, Laboratoire Universitaire de Biodiversité et Écologie Microbienne, F-29000, Quimper, France. Electronic address:
Despite their acidic pH, carbonated beverages can be contaminated by spoilage microorganisms. Thermal treatments, before and/or after carbonation, are usually applied to prevent the growth of these microorganisms. However, the impact of CO on the heat resistance of spoilage microorganisms has never been studied.
View Article and Find Full Text PDFSci Rep
June 2024
Ifremer, Univ. Brest, CNRS, IRD, Laboratoire d'Océanographie Physique et Spatiale (LOPS), IUEM, 29280, Plouzané, France.
Both unresolved physics in numerical models and limited theoretical understanding of the small-scale diffusion processes occurring near the ocean surface hamper predictability of tropical cyclone (TC) wind changes. An analytical model is here developed to diagnose the short-term evolution of the TC wind profile. An effective frictional parameter is introduced to control the unknown diffusion effects.
View Article and Find Full Text PDFJ Neuroeng Rehabil
May 2024
Service de Rééducation Neurolocomotrice, Unité de Neurorééducation, AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, F-94010, France.
Background: Movement smoothness is a potential kinematic biomarker of upper extremity (UE) movement quality and recovery after stroke; however, the measurement properties of available smoothness metrics have been poorly assessed in this group. We aimed to measure the reliability, responsiveness and construct validity of several smoothness metrics.
Methods: This ancillary study of the REM-AVC trial included 31 participants with hemiparesis in the subacute phase of stroke (median time since stroke: 38 days).
Nat Commun
May 2024
Univ Rouen Normandie, Inserm, UMR 1234, F-76000, Rouen, France.
Glucocorticoid (GC) resistance in childhood relapsed B-cell acute lymphoblastic leukemia (B-ALL) represents an important challenge. Despite decades of clinical use, the mechanisms underlying resistance remain poorly understood. Here, we report that in B-ALL, GC paradoxically induce their own resistance by activating a phospholipase C (PLC)-mediated cell survival pathway through the chemokine receptor, CXCR4.
View Article and Find Full Text PDFAnn Dermatol Venereol
June 2024
French National Reference Center for Toxic Bullous Diseases and Severe Drug Reactions TOXIBUL, Filière FIMARAD, Créteil, France.
Database (Oxford)
May 2024
Translational Medicine Division, Research Branch, Sidra Medicine, Doha 26999, Qatar.
In the field of complex autoimmune diseases such as systemic lupus erythematosus (SLE), systems immunology approaches have proven invaluable in translational research settings. Large-scale datasets of transcriptome profiling have been collected and made available to the research community in public repositories, but remain poorly accessible and usable by mainstream researchers. Enabling tools and technologies facilitating investigators' interaction with large-scale datasets such as user-friendly web applications could promote data reuse and foster knowledge discovery.
View Article and Find Full Text PDFJ Neuroradiol
June 2024
Neuroradiology, CHU Brest; LaTIM (INSERM UMR 1101), Univ. Brest, 29238 Brest Cedex 3, France. Electronic address:
Psychol Sport Exerc
September 2024
Univ Brest, Laboratory CREAD, F-29200 Brest, France.
Considering mindfulness as a multidimensional disposition domain-specific skill and state, this study aimed to explore the effect of the dimensions of mindfulness on the trajectories of biopsychosocial stress-recovery balance and on HRV over 10 days of a pre-competitive cycle. 24 young BMX riders completed mindfulness disposition and domain-specific skill scales. Monitoring of the recovery-stress states was based on biopsychosocial measurements (daily and biweekly).
View Article and Find Full Text PDFComput Biol Med
July 2024
LaTIM UMR 1101, Inserm, Brest, France.
Multimodal medical imaging plays a pivotal role in clinical diagnosis and research, as it combines information from various imaging modalities to provide a more comprehensive understanding of the underlying pathology. Recently, deep learning-based multimodal fusion techniques have emerged as powerful tools for improving medical image classification. This review offers a thorough analysis of the developments in deep learning-based multimodal fusion for medical classification tasks.
View Article and Find Full Text PDFMar Drugs
April 2024
CNRS, Institut de Chimie des Substances Naturelles, Université Paris-Saclay, 91190 Gif-sur-Yvette, France.
As a result of screening a panel of marine organisms to identify lead molecules for the stimulation of endochondral bone formation, the calcareous sponge was identified to exhibit significant activity during endochondral differentiation. On further molecular networking analysis, dereplication and chemical fractionation yielded the known clathridine A-related metabolites and the homodimeric complex (clathridine A) Zn (), together with the new unstable heterodimeric complex (clathridine A-clathridimine)Zn (). With the presence of the zinc complexes annotated through the LC-MS analysis of the crude extract changing due to the instability of some metabolites and complexes constituting the mixture, we combined the isolation of the predicted molecules with their synthesis in order to confirm their structure and to understand their reactivity.
View Article and Find Full Text PDFMar Environ Res
June 2024
Food and Agriculture Organization of the United Nations, Viale Delle Terme di Caracalla, 00153, Rome, Italy; South African Institute for Aquatic Biodiversity, Private Bag 1015, Makhanda, 6140, South Africa.
Cold water corals (CWC) provide habitats for many organisms including demersal fish. Bottom trawl observations have indicated a co-occurrence of the fish Helicolenus dactylopterus with CWC reefs, but a detailed understanding of this relation is lacking. To better understand the nature of this relation we have analyzed 85 video-lines from ROV dives conducted at 25-1700 m depth off Morocco, Mauritania, and Senegal in 2020 and 2021.
View Article and Find Full Text PDFSci Rep
May 2024
LaTIM UMR 1101, Inserm, Brest, France.
In the realm of ophthalmology, precise measurement of tear film break-up time (TBUT) plays a crucial role in diagnosing dry eye disease (DED). This study aims to introduce an automated approach utilizing artificial intelligence (AI) to mitigate subjectivity and enhance the reliability of TBUT measurement. We employed a dataset of 47 slit lamp videos for development, while a test dataset of 20 slit lamp videos was used for evaluating the proposed approach.
View Article and Find Full Text PDFSci Rep
May 2024
Laboratoire des Fluides Complexes et leurs Réservoirs - IPRA, E2S-UPPA, TotalEnergies, CNRS, Université de Pau et des Pays de l'Adour, UMR5150, Pau, France.
Serpentinization is commonly presented as the main source of natural hydrogen (H) in the continental domains. However, recent works in Australia and Brazil showed that Archean-Paleoproterozoic banded iron formations could be another natural source of H gas. Although the reaction that produces hydrogen is similar (Fe oxidation-HO reduction process), the iron content may be higher in banded iron formations than in mafic igneous lithologies, potentially generating H more efficiently.
View Article and Find Full Text PDFFront Immunol
May 2024
Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Univ Brest, Inserm, Centre Hospitalier Universitaire (CHU) de Brest, UMR1227, Brest, France.
Imaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting respectively the detailed histopathological analysis of IMC-produced images and its application to small selected tissue regions of interest (ROI) of one to few square millimeters. Coupling on a single-tissue section, IMC and histopathological analyses could permit a better selection of the ROI for IMC analysis as well as co-analysis of immunophenotyping and histopathological data until the single-cell level.
View Article and Find Full Text PDFNew Phytol
July 2024
Department of Biotechnology and Food Science, Norwegian University of Science and Technology, N-7491, Trondheim, Norway.
Diatoms are a diverse group of phytoplankton usually dominating areas characterized by rapidly shifting light conditions. Because of their high growth rates and interesting biochemical profile, their biomass is considered for various commercial applications. This study aimed at identifying strains with superior growth in a photobioreactor (PBR) by screening the natural intraspecific diversity of ecotypes isolated from different habitats.
View Article and Find Full Text PDFClin Immunol
July 2024
LBAI, UMR1227, Univ Brest, Inserm, Brest, France. Electronic address:
Objective: To link changes in the B-cell transcriptome from systemic lupus erythematosus (SLE) patients with those in their macroenvironment, including cellular and fluidic components.
Methods: Analysis was performed on 363 patients and 508 controls, encompassing transcriptomics, metabolomics, and clinical data. B-cell and whole-blood transcriptomes were analysed using DESeq and GSEA.
Microbiol Res
August 2024
Ifremer, Univ Brest, CNRS, IRD, LEMAR, Plouzané F-29280, France. Electronic address:
Vibrio parahaemolyticus is the leading bacterial cause of gastroenteritis associated with seafood consumption worldwide. Not all members of the species are thought to be pathogenic, thus identification of virulent organisms is essential to protect public health and the seafood industry. Correlations of human disease and known genetic markers (e.
View Article and Find Full Text PDFMar Pollut Bull
June 2024
Biologie des Organismes et Écosystèmes Aquatiques (BOREA) UMR 8067 MNHN, CNRS SU, IRD 207, UA, 61 Rue Buffon CP 53, 75005 Paris, France; Univ Brest, CNRS, IRD, IUEM, F-29280 Plouzané, France. Electronic address:
In marine invertebrates, abiotic stresses on adults can act directly on gametes quality, which impacts phenotype and development success of the offspring. Human activities introduce noise pollution in the marine environment but still few studies on invertebrates have considered the impacts on adult or larval stages separately, and to our knowledge, never investigated the cross-generational effects of anthropogenic noise. This article explores parental effects of pile driving noise associated with the building phase of offshore wind turbines on a coastal invertebrate, Pecten maximus (L.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
November 2024
Dermatology Department, Brest University Hospital, Brest, France.
Curr Opin Biotechnol
June 2024
Biomolécules et Biotechnologies Végétales, EA2106, Université de Tours, 37200 Tours, France. Electronic address:
Plant bioactives hold immense potential in the medicine and food industry. The recent advancements in omics applied in deciphering specialized metabolic pathways underscore the importance of high-quality genome releases and the wealth of data in metabolomics and transcriptomics. While harnessing data, whether integrated or standalone, has proven successful in unveiling plant natural product (PNP) biosynthetic pathways, the democratization of machine learning in biology opens exciting new opportunities for enhancing the exploration of these pathways.
View Article and Find Full Text PDFSci Rep
May 2024
Univ Brest, CNRS, IFREMER, IRD, Laboratoire d'Océanographie Physique et Spatiale (LOPS, UMR 6523), IUEM, Brest, France.
Along with the mean sea level rise due to climate change, the sea level exhibits natural variations at a large number of different time scales. One of the most important is the one linked with the seasonal cycle. In the Northern Hemisphere winter, the sea level is as much as 20 cm below its summer values in some locations.
View Article and Find Full Text PDFJ Appl Microbiol
May 2024
Univ Brest, CNRS, IRD, Ifremer, LEMAR, IUEM, F-29280 Plouzané, France.
Aims: Macroalgae harbor a rich epiphytic microbiota that plays a crucial role in algal morphogenesis and defense mechanisms. This study aims to isolate epiphytic cultivable microbiota from Ulva sp. surfaces.
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