1 results match your criteria: "United StatesgUniversity of Illinois at Urbana-Champaign[Affiliation]"

Ratiometric analysis of in vivo retinal layer thicknesses in multiple sclerosis.

J Biomed Opt

September 2016

University of Illinois at Urbana-Champaign, Beckman Institute for Advanced Science and Technology, 405 North Mathews Avenue, Urbana, Illinois 61801, United StatescUniversity of Illinois at Urbana-Champaign, Department of Electrical and Computer Engineering, 619 South Wright Street, Champaign, Illinois 61820, United StatesfUniversity of Illinois at Urbana-Champaign, Department of Bioengineering, 1304 West Springfield Avenue, Urbana, Illinois 61801, United StatesgUniversity of Illinois at Urbana-Champaign, Department of Internal Medicine, 506 South Mathews Avenue, Urbana, Illinois 61801, United States.

We performed ratiometric analysis of retinal optical coherence tomography images for the first time in multiple sclerosis (MS) patients. The ratiometric analysis identified differences in several retinal layer thickness ratios in the cohort of MS subjects without a history of optic neuritis (ON) compared to healthy control (HC) subjects, and there was no difference in standard retinal nerve fiber layer thickness (RNFLT). The difference in such ratios between HC subjects and those with mild MS-disability, without a difference in RNFLT, further suggests the possibility of using layer ratiometric analysis for detecting early retinal changes in MS.

View Article and Find Full Text PDF