2 results match your criteria: "United States. Electronic address: asuvorov@schoolph.umass.edu.[Affiliation]"
Peripubertal serum dioxin concentrations and subsequent sperm methylome profiles of young Russian adults.
Reprod Toxicol
June 2018
Department of Genomics and Human Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 3 Gubkina St., 119991, Moscow, Russia; Chapaevsk Medical Association, 3a Meditsinskaya st., 446100, Chapaevsk, Samara region, Russia; A.N. Belozersky Research Institute of Physico-Chemical Biology, Moscow State University, Leninskye Gory, House 1, Building 40, 119992, Moscow, Russia. Electronic address:
Background: The association of exposure to endocrine disrupting chemicals in the peripubertal period with subsequent sperm DNA methylation is unknown.
Objective: We examined the association of peripubertal serum 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) concentrations with whole-genome bisulfite sequencing (WGBS) of sperm collected in young adulthood.
Methods: The Russian Children's Study is a prospective cohort of 516 boys who were enrolled at 8-9 years of age and provided semen samples at 18-19 years of age.
Perinatal exposure to 2,2',4'4' -Tetrabromodiphenyl ether induces testicular toxicity in adult rats.
Toxicology
August 2017
Department of Environmental Health Sciences, University of Massachusetts Amherst,686 N. Pleasant St., 149A Goessmann, Amherst, MA, 01003-9303, United States. Electronic address:
Since 1965, polybrominated diphenyl ethers (PBDEs) have been used internationally as flame-retardant additives. PBDEs were recently withdrawn from commerce in North America and Europe due to their environmental persistence, bioaccumulative properties and endocrine-disrupting effects. Generations exposed perinatally to the highest environmental doses of PBDE account for one-fifth of the total United States population.
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