Emerging trends in cannabis administration for women with chronic pain.

Cannabis use among women who experience chronic pain is on the rise in the United States. However, little is known about women's motives and preferences for cannabis administration. The purpose of this study was to characterize cannabis use among women with chronic pain.

An examination of immersive journalism by bibliometric analysis from 1999 to 2023.

Immersive journalism is an innovative storytelling approach that aims to enable the audience to experience the event or situation in the news using virtual reality, unlike traditional news narration. In this study, the literature related to the subject was searched using the keywords Immersive Journalism, 360-Degree Video, Narrative journalism, Newsgame, VR Storytelling through the Web of Science database and a data set was created from 955 publications between 1999 and 2023. No filter was applied to the studies in the data set of the study and articles, books, and early access publications as well as book chapters, editorial materials or conference proceedings in the Web of Science database were included in the study.

Evaluating and Improving the Quality of Surgical Operative Notes at the Port Sudan Teaching Hospital.

Background Thorough and standardized documentation of operative notes is essential for effective communication, patient safety, legal protection, and the continuity of care. However, in many hospitals in Sudan, surgeons often use non-standardized methods, resulting in inconsistent and incomplete records. This study evaluates the quality of operative notes at the Port Sudan Teaching Hospital using the Royal College of Surgeons of England (RCSEng) guidelines, aiming to improve compliance and documentation practices.

Impact of Sports on Female Growth and Pubertal Development: A Cohort Study.

Introduction The participation of women in sports is increasing, and the rising training demands may impact growth and pubertal development. High-intensity sports are often linked to delayed growth and bone maturation due to energy deficits and intense regimens. These factors may increase the risk of injury and musculoskeletal issues.

The Impact of Orthodontic Treatment on Body Weight Due to Change in Dietary Habits.

Background Orthodontic treatment, while primarily focusing on correcting dental alignment and occlusion, has been increasingly validated for its potential impact on broader aspects of oral health and general well-being: its potential influence on body weight. While the mechanical effects of orthodontic appliances are well documented in the literature, their potential behavioral impact on weight loss remains underexplored. Beyond its primary role in correcting dental alignment, our study has unveiled a lesser-known benefit: its potential to aid in weight reduction among individuals who have already struggled through conventional methods.

Unguarded liabilities: complex amino acid dependence exposes unique avenues of inhibition.

Recent reports from the Centers for Disease Control and Prevention approximate 500,000 cases of Lyme disease in the United States yearly, a significant economic burden on the healthcare system. The standard treatment for Lyme disease includes broad-spectrum antibiotics, which may be administered for extensive periods of time and result in significant impacts to the patient. Recently, we demonstrated that , the causative agent of Lyme disease, is uniquely dependent upon peptide acquisition via an oligopeptide transport (Opp) system.

Mycobactin analogue interacting with siderophore efflux-pump protein: insights from molecular dynamics simulations and whole-cell assays.

Introduction: In response to continued public health emergency of antimicrobial resistance (AMR), a significant key strategy is the discovery of novel mycobacterial efflux-pump inhibitors (EPIs) as potential adjuvants in combination drug therapy. Interest in identifying new chemotypes which could potentially synergize with the existing antibiotics and can be deployed as part of a combination therapy. This strategy could delay the emergence of resistance to existing antibiotics and increase their efficacy against resistant strains of mycobacterial species.

Increased usage of doxycycline for young children with Lyme disease.

Background: The 2018 Infectious Disease Committee of the American Academy of Pediatrics stated that up to 3 weeks or less of doxycycline is safe in children of all ages. Our goal was to examine trends in doxycycline treatment for children with Lyme disease.

Methods: We assembled a prospective cohort of children aged 1 to 21 years with Lyme disease who presented to one of eight participating Pedi Lyme Net centers between 2015 and 2023.

Defense mechanisms of against antibiotics: a review.

is a foodborne pathogenic bacterium that causes salmonellosis worldwide. Also, is considered a serious problem for food safety and public health. Several antimicrobial classes including aminoglycosides, tetracyclines, phenols, and β-Lactams are used to treat infections.

A retrospective review of the common childhood illnesses and the indications for antibiotic prescription at community hospital in Malawi.

Background: Childhood remains a vulnerable period and a key determiner for adult health. Various illnesses experienced by children in their early years determine future performance and contribution to society. Acute and chronic infectious diseases, undernutrition, and early childhood non-communicable diseases have greatly been linked to intellectual disability, poor childhood development, increased morbidity, and household and healthcare economic costs.

A machine learning-based strategy to elucidate the identification of antibiotic resistance in bacteria.

Microorganisms, crucial for environmental equilibrium, could be destructive, resulting in detrimental pathophysiology to the human host. Moreover, with the emergence of antibiotic resistance (ABR), the microbial communities pose the century's largest public health challenges in terms of effective treatment strategies. Furthermore, given the large diversity and number of known bacterial strains, describing treatment choices for infected patients using experimental methodologies is time-consuming.

Antibiogram profiles of pathogenic and commensal bacteria in goat and sheep feces on smallholder farm.

Introduction: The increase of antimicrobial resistance (AMR) in zoonotic pathogens poses a substantial threat to both animal production and human health. Although large-scale animal farms are acknowledged as major reservoirs for AMR, there is a notable knowledge gap concerning AMR in small-scale farms. This study seeks to address this gap by collecting and analyzing 137 fecal samples from goat and sheep farms in Tennessee and Georgia.

Engineering the Novel Extremophile Alga for High Lipid and High Starch Production as a Path to Developing Commercially Relevant Strains.

Microalgae offer a compelling platform for the production of commodity products, due to their superior photosynthetic efficiency, adaptability to nonarable lands and nonpotable water, and their capacity to produce a versatile array of bioproducts, including biofuels and biomaterials. However, the scalability of microalgae as a bioresource has been hindered by challenges such as costly biomass production related to vulnerability to pond crashes during large-scale cultivation. This study presents a pipeline for the genetic engineering and pilot-scale production of biodiesel and thermoplastic polyurethane precursors in the extremophile species .

Exploring links between visuospatial ability and anatomy learning in education: A bibliometric analysis and scientific mapping.

The field of medical education faces a significant challenge in teaching human anatomy, a fundamental aspect of medical science that is often perceived as complex and demanding. Understanding the shapes and anatomical structure locations is crucial for students to master the intricacies of anatomy. Visuospatial ability, which involves comprehending three-dimensional structures and their spatial relationships, plays a pivotal role in anatomy learning.

Regional trends in colorectal cancer mortality in people aged 45-84 years in the US, 1999-2022.

Background: Colorectal cancer (CRC) screening via colonoscopy is now advised for most adults beginning at age 45 years, an update from the earlier recommendation of age 50 years. With the increase in CRC screening rates, it is crucial to examine how mortality rates have changed over time. The aim of this study is to identify trends and regional differences in CRC mortality over the last two decades, specifically in individuals within the CRC recommended screening age group.

The Future Hospital in Global Health Systems: The Future Hospital Within the Healthcare System.

Future hospitals must be able to adapt in many ways to the changing demands on their roles and functions within evolving healthcare delivery infrastructures. These include changing population structures and needs, new models of healthcare provision, technological advances, and innovations in design, all while enhancing their environmental sustainability. This article sets out the issues that those determining healthcare policy and designing future hospitals must consider if they are to become and remain fit for purpose within the wider health and social care system.

Participation in mainstream community groups by older United States adults with intellectual and developmental disabilities: A multiple case study.

Background: Adults with intellectual and developmental disabilities want to be included in all aspects of community life, but social inclusion continues to be very limited.

Method: We used a qualitative multiple case study to describe the experiences and perspectives of four older workers or retirees with intellectual and developmental disabilities aged 45 to 63 who each participated in a different socially inclusive community group.

Results: Three themes emerged: finding a good match; support for participation; and the outcomes of participating in a mainstream community group.

A deep learning feature importance test framework for integrating informative high-dimensional biomarkers to improve disease outcome prediction.

Many human diseases result from a complex interplay of behavioral, clinical, and molecular factors. Integrating low-dimensional behavioral and clinical features with high-dimensional molecular profiles can significantly improve disease outcome prediction and diagnosis. However, while some biomarkers are crucial, many lack informative value.

Photochromic Sodalites: From Natural Minerals to Advanced Applied Materials.

ConspectusWhile photochromic natural sodalites, an aluminosilicate mineral, were originally considered as curiosities, articles published in the past ten years have radically changed this perspective. It has been proven that their artificial synthesis was easy and allowed compositional tuning. Combined with simulations, it has been shown that a wide range of photochromic properties were achievable for synthetic sodalites (color, activation energy, reversibility, etc.

Orientation-Dependent Anisotropic Desalination by Assembled Zeolite Nanotube Membranes.

Porous nanomaterials have shown great promise in many desalination applications. Zeolite nanotubes, featuring abundant but inhomogeneous nanopores on their surface, have been recently synthesized in experiments; however, their capacity for desalination is not yet understood. In this work, we use molecular dynamics simulations to investigate the capability of assembled zeolite nanotube membranes to perform in desalination applications due to their inherent multiscale porous properties.

Alcohol withdrawal syndrome presentations to emergency departments in the United States from 2015 to 2023.

Introduction: Alcohol withdrawal syndrome (AWS) is a common condition prompting emergency department (ED) presentation. However, there are limited recent, large-scale, robust data available on the incidence, admission, and medical treatment of AWS in the ED.

Methods: This was a retrospective cohort study of ED presentations for AWS from January 1, 2016, to December 31, 2023, using Epic Cosmos.

Predicting Chlorophyll- Concentrations in the World's Largest Lakes Using Kolmogorov-Arnold Networks.

Accurate prediction of chlorophyll- (Chl-) concentrations, a key indicator of eutrophication, is essential for the sustainable management of lake ecosystems. This study evaluated the performance of Kolmogorov-Arnold Networks (KANs) along with three neural network models (MLP-NN, LSTM, and GRU) and three traditional machine learning tools (RF, SVR, and GPR) for predicting time-series Chl- concentrations in large lakes. Monthly remote-sensed Chl- data derived from Aqua-MODIS spanning September 2002 to April 2024 were used.

Best Interests and Decisions to Withdraw Life-Sustaining Treatment from a Conscious, Incapacitated Patient.

Conscious but incapacitated patients need protection from both undertreatment and overtreatment, for they are exceptionally vulnerable, and dependent on others to act in their interests. In the United States, the law prioritizes autonomy over best interests in decision making. Yet U.