2 results match your criteria: "United Kingdom. ws.wassif@bedfordhospital.nhs.uk[Affiliation]"
Steroid metabolism and excretion in anorexia nervosa.
Vitam Horm
December 2013
Department of Clinical Biochemistry, Bedford Hospital NHS Trust, Kempston Road, MK42 9DJ Bedford, United Kingdom.
Few organ systems are spared the progressive deterioration seen in critically ill patients with anorexia nervosa. Most of the endocrine disturbances discussed are due to starvation and represent appropriate metabolic adaptation of the body to food restriction and negative energy balance. In a starving patient, a lowered metabolic rate, increased cortisol and growth hormone level and reduced fertility are all appropriate adaptations to an abnormal and highly stressful state.
View Article and Find Full Text PDFSteroid metabolism and excretion in severe anorexia nervosa: effects of refeeding.
Am J Clin Nutr
May 2011
Department of Clinical Biochemistry, King's College Hospital National Health Service Foundation Trust, London, United Kingdom.
Background: To our knowledge, changes in steroid metabolism in subjects with anorexia nervosa (AN) after weight gain have not been elucidated.
Objective: We characterized urinary steroid excretion and metabolism in AN patients and investigated the effects of refeeding.
Design: In an intervention study, we recruited 7 women with life-threatening weight loss upon admission and after a median [interquartile range (IQR)] of 95 d (88-125 d) of intensive refeeding; 15 age-matched women were recruited as control subjects.