1,132,237 results match your criteria: "United Kingdom; Lucena Clinic Child and Adolescent Mental Health Service[Affiliation]"

Correction: Decision-Making, Pro-variance Biases and Mood-Related Traits.

Comput Psychiatr

January 2025

Max Planck University College London Centre for Computational Psychiatry and Ageing Research, University College London, London WC1B 5EH, United Kingdom.

[This corrects the article DOI: 10.5334/cpsy.114.

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Evidence-based medicine integrates clinical research, personal expertise, and patient values. The most robust forms of clinical evidence, such as randomized controlled trials (RCTs) and prospective studies, provide the strongest support for medical decision-making. RCTs are vital in radiology for evaluating new imaging technologies, contrast agents, and therapeutic procedures, despite challenges in translating preclinical findings to clinical practice.

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Any scientific journal of repute constantly strives to ensure the highest possible quality, integrity, and ethical standards of published research. This article attempts to the highlight multifaceted responsibilities of an Editor in Chief (EiC) and editors such as managing the peer review process, detecting plagiarism, and ensuring quality of selected manuscript before publication. The EiC also has to tackle issues of salami slicing, duplicate submissions, secondary publications, and guest and ghost authorship while adhering to constantly evolving guidelines of the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE).

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Clinical Outcomes in Patients Undergoing Sequential Intragastric Balloon (IGB) Treatment for Super Obesity: A Single Centre Retrospective Analysis.

J Metab Bariatr Surg

December 2024

Department of General Surgery, Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, Yorkshire, United Kingdom.

Purpose: We aimed to assess outcomes in patients undergoing sequential intragastric balloon (IGB) treatment for obesity.

Materials And Methods: Consecutive patients who underwent treatment between May 2014 and February 2023 were identified. We recorded outcomes including: weight at 3-monthly intervals, progression to definitive bariatric procedure and morbidity.

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Selecting repetitive focal and rotational activation patterns with the highest probability of being a source of atrial fibrillation.

J Mol Cell Cardiol Plus

March 2024

Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), University Maastricht, Maastricht, the Netherlands.

Introduction: Repetitive focal and rotational activation patterns are currently used as additional ablation targets for atrial fibrillation (AF). However, there is no evidence that all these detected targets are actual sources of AF. In this paper, we present an approach that detects and ranks AF activation patterns not only based on the degree of pattern repetitiveness but also on the extent to which they are able to entrain their vicinity.

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Background: In persistent atrial fibrillation (AF), localized extra-pulmonary vein sources may contribute to arrhythmia recurrences after pulmonary vein isolation. This in-silico study proposes a high-density sequential mapping strategy to localize such sources.

Method: Catheter repositioning was guided by repetitive conduction patterns, moving against the prevailing conduction direction (upstream) toward the sources.

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Primary or secondary hypogammaglobulinemia is associated with persistent norovirus and infections despite immunoglobulin replacement therapy. Allogeneic hematopoietic cell transplantation for hematologic indications can lead to immune reconstitution by correcting a previously undiagnosed concurrent primary immunodeficiency.

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Repairing the mitral valve without touching the mitral valve-a novel technique.

J Surg Case Rep

January 2025

Department of Cardiac Surgery, Royal Papworth Hospital, Papworth Road, Cambridge Biomedical Campus, Cambridge, Cambridgeshire CB2 0AY, United Kingdom.

A 44-year-old gentleman presented with severe ischemic cardiomyopathy and mitral regurgitation post-inferior myocardial infarction. Echocardiography and magnetic resonance imaging revealed a dilated left ventricle with a large left ventricular aneurysm (9.3 × 9.

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A case report and literature review of De Garengeot hernia.

J Surg Case Rep

January 2025

Department of General Surgery, Weston General Hospital, University Hospitals Bristol and Weston NHS Trust, Grange Road Uphill, Weston-Super-Mare, Bristol BS23 4TQ, United Kingdom.

The presence of an appendix in the femoral hernia, known as De Garengeot hernia, was first described by a French surgeon named Rene Jacques Croissant de Garengeot in 1731. It is a rare surgical entity occurring in only 0.5-5% of all femoral hernias.

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Brachytherapy is a key treatment for gynaecological malignancies, delivering high doses to the tumour volume whilst sparing nearby normal tissues due to its steep dose gradient. Accuracy is imperative as small shifts can lead to clinically significant under- or over-dosing of the target volume or organs at risk (OARs), respectively. Independent verification of dose delivered during brachytherapy is not routinely performed but it is important to identify gross errors and define action thresholds to guide inter-fraction treatment decisions.

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Purpose: Differentiating primary central nervous system lymphoma (PCNSL) and glioblastoma (GBM) is crucial because their prognosis and treatment differ substantially. Manual examination of their histological characteristics is considered the golden standard in clinical diagnosis. However, this process is tedious and time-consuming and might lead to misdiagnosis caused by morphological similarity between their histology and tumor heterogeneity.

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Background: Confidence in pregnancy outcome data for women with bipolar disorder is compromised by small cohort sizes. However, comprehensive national data have been published over the last decade, but no quantitative synthesis has been established to determine the factors associated with complications in these women. Our goal is to summarise the evidence of population-based data on obstetric complications and neonatal outcomes in women with bipolar disorder compared to women without bipolar disorder.

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Background: Cardiogenic shock (CS) is a heterogeneous clinical syndrome, making it challenging to predict patient trajectory and response to treatment. This study aims to identify biological/molecular CS subphenotypes, evaluate their association with outcome, and explore their impact on heterogeneity of treatment effect (ShockCO-OP, NCT06376318).

Methods: We used unsupervised clustering to integrate plasma biomarker data from two prospective cohorts of CS patients: CardShock (N = 205 [2010-2012, NCT01374867]) and the French and European Outcome reGistry in Intensive Care Units (FROG-ICU) (N = 228 [2011-2013, NCT01367093]) to determine the optimal number of classes.

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Social Media Growth Blueprint for Plastic Surgeons: Insights and Considerations From Personal Experience.

Plast Reconstr Surg Glob Open

January 2025

From the Department of Plastic and Reconstructive Surgery, Sheffield Teaching Hospitals, Sheffield, United Kingdom.

Background: Social media platforms such as TikTok have recently emerged as influential tools for information dissemination, offering plastic surgeons new opportunities to promote their practices. However, these platforms also present significant challenges regarding online safety, ethical considerations, and the potential spread of misinformation.

Methods: This study analyzes the experience of gaining 100,000 followers on TikTok within 6 months, highlighting the excitement of rapid growth alongside the challenges posed by the potential for misinformation.

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Aim And Background: Fluid resuscitation is the first-line treatment for patients with diabetic ketoacidosis (DKA). However, the optimal choice of resuscitative fluid remains controversial. This study aims to evaluate the impact of balanced electrolyte solution (BES) compared to 0.

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Reply.

Ophthalmol Sci

December 2024

Institute of Ophthalmology, University College London, London, United Kingdom.

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Differentiating Choroidal Melanomas and Nevi Using a Self-Supervised Deep Learning Model Applied to Clinical Fundoscopy Images.

Ophthalmol Sci

November 2024

Liverpool Ocular Oncology Research Group, Department of Eye and Vision Science, Institute of Life Course and Medical Sciences (ILCaMS), University of Liverpool, Liverpool, United Kingdom.

Purpose: Testing the validity of a self-supervised deep learning (DL) model, RETFound, for use on posterior uveal (choroidal) melanoma (UM) and nevus differentiation.

Design: Case-control study.

Subjects: Ultrawidefield fundoscopy images, both color and autofluorescence, were used for this study, obtained from 4255 patients seen at the Liverpool Ocular Oncology Center between 1995 and 2020.

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This study investigates the impact of gamification on response inhibition in a Stop-Signal Task (SST) and examines participants' gamification experience. The findings reveal that, after accounting for approach- and avoidance-motivation as well as impulsiveness, higher immersion is associated with impaired response inhibition. This effect could be attributed to a substantial decline in immersion between the first and second SST sessions.

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Recent advancements in nanoscience underscore the transformative potential of nanomaterials in environmental and biological applications. In this study, we synthesized gold nanoparticles (Au@ NPs) using an eco-friendly and cost-effective approach, leveraging peel extract as both a capping and reducing agent. This method presents a sustainable alternative to traditional chemical agents.

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Pesticide use in Bangladesh is disproportionately high in vegetable farming compared to other crops like cereals, pulses, and cash crops. This study delves into the knowledge, attitudes, and practices regarding pesticide use among vegetable farmers, focusing on the impact of a digital aggregation service implemented by Digital Green. Based on interviews with 120 vegetable farmers in the LOOP aggregation scheme and 120 non-LOOP vegetable farmers this study indicates that the farmers using the aggregation service have a moderately higher level of food safety knowledge.

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It has been twenty-three years since China acceded to the WTO. Since then, China has participated in high-profile disputes through the WTO's DSM. During this period, China has evolved from being a silent observer to a sophisticated participant in the DSM.

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Acute Effects of Unplanned and Planned Hop-Landing Training on Neurocognitive Function and Knee Biomechanics.

Orthop J Sports Med

January 2025

School of Sport, Rehabilitation, and Exercise Sciences, University of Essex, Wivenhoe Park, Colchester, Essex, United Kingdom.

Background: Athletes with decreased baseline neurocognitive function may experience noncontact anterior cruciate ligament (ACL) injury in unanticipated athletic situations. Many ACL injury prevention programs (IPPs) focus on improving closed-skill movements (eg, planned landing). However, the more open-skill movements (eg, unplanned reactive movements) required in unpredictable sports scenarios are commonly absent from ACL IPPs, and the acute effects of open-skill training on neurocognitive function remain unclear.

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 Urinary tract infections (UTIs) represent a rare postoperative complication following thyroidectomy.  This study aimed to assess the clinicodemographic factors associated with the development of UTIs and subsequent outcomes among patients undergoing thyroidectomy.  This retrospective study used the National Surgical Quality Improvement Program (NSQIP) database to analyze patients who underwent thyroidectomy from 2005 to 2019.

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The Comprehensive Proarrhythmia Assay (CiPA) evaluates drug-induced torsade de pointes (TdP) risk, with qNet commonly used to classify drugs into low-, intermediate-, and high-risk categories. While most studies focus on single-drug effects, 2-drug fixed-dose combination (FDC) therapy is widely used for cardiovascular disease management. We aimed to develop the CiPA-based methodology to predict adverse effects of FDC therapy.

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