EMG Dataset for Gesture Recognition with Arm Translation.

Myoelectric control has emerged as a promising approach for a wide range of applications, including controlling limb prosthetics, teleoperating robots and enabling immersive interactions in the Metaverse. However, the accuracy and robustness of myoelectric control systems are often affected by various factors, including muscle fatigue, perspiration, drifts in electrode positions and changes in arm position. The latter has received less attention despite its significant impact on signal quality and decoding accuracy.

Post-colonoscopy cancer rates in Scotland from 2012 to 2018: A population-based cohort study.

Aim: The aim of this work was to quantify post-colonoscopy colorectal cancer (PCCRC) rates in National Health Service (NHS) Scotland using World Endoscopy Association guidelines, compare incidence between health boards and referral streams and explore comparisons in results with published data from other healthcare systems.

Method: This is a population-based cohort study using NHS Scotland data between 2012 and 2018. All people undergoing colonoscopy between 2012 and 2018 and subsequently diagnosed as having bowel cancer up to 3 years after their investigation were included.

Diabetic foot ulcer in the Western Pacific Region: Current data on ulceration rates and microbial profiles, gaps and charting strategies.

The Western Pacific Region hosts the largest proportion of people with diabetes. Despite being a key diabetes-related complication, diabetic foot ulcer has been neglected in both prevention and treatment efforts. This narrative review highlights available data on the burden (either prevalence or incidence), as well as microbial profiles of diabetic foot ulcers in the Western Pacific Region, identifies data gaps, and discusses strategies to address these gaps.

Guidance on the assessment of the functionality of biomaterials for periodontal tissue regeneration: Methodologies and testing procedures.

Innovative biomaterials and tissue engineering strategies show great promise in regenerating periodontal tissues. This guidance provides an overview and detailed recommendations for evaluating the biological functionality of these new biomaterials in vitro, focusing on mineralization, immunomodulatory effects, cellular differentiation, and angiogenesis. Additionally, it discusses the use of in vivo experimental models that mimic periodontitis and scrutinizes methods such as osteogenic differentiation, immunomodulation, and anti-inflammatory responses to assess the effectiveness of these biomaterials in promoting periodontal tissue reconstruction.

Identifying people at risk of rheumatoid arthritis in primary care: qualitative study.

Background: Identification of rheumatoid arthritis (RA) in primary care is challenging and often delayed. Anti-cyclic citrullinated peptide (anti-CCP) antibody testing of people presenting to primary care with new-onset musculoskeletal symptoms without synovitis could help address this; those testing positive are at increased risk of developing RA.

Aim: To explore how primary care clinicians currently identify and refer patients with suspected RA, and the behaviours required to implement a prediction model for guiding targeted anti-CCP testing for non-specific musculoskeletal symptoms in primary care.

Symptom appraisal and help-seeking before a cancer diagnosis during pregnancy: a qualitative study.

Background Estimated incidence of cancer diagnosis during or shortly after pregnancy is 1 in 1,000 women. Pregnancy can impact symptom appraisal and help-seeking for symptoms subsequently diagnosed as cancer. Little is known about the pathway to cancer diagnosis in pregnancy or delays that women can encounter.

Antidepressants and risk of postural hypotension: a self-controlled case series study.

Background Antidepressants are associated with postural hypotension (PH), but it is not typically recognised as a common adverse effect. PH is linked with serious complications in older adults (e.g.

The effect of a general practitioner's perception of a patient request for antibiotics on antibiotic prescribing for respiratory tract infections: secondary analysis of a point prevalence audit survey in 18 European countries.

Background: Illness severity, comorbidity, fever, age and symptom duration influence antibiotic prescribing for respiratory tract infections (RTI). Non-medical determinants, such as patient expectations, also impact prescribing.

Aim: To quantify the effect of general practitioners' (GPs') perception of a patient request for antibiotics on antibiotic prescribing for RTI and investigate effect modification by medical determinants and country.

Barriers to and facilitators of women general practitioners' careers: a systematic review.

Background: Despite women comprising 52% of full-time equivalent general practitioners (GPs) in England, a significant gender pay gap persists (15% after adjustments). Further understanding of the barriers and facilitators impacting women GPs' careers is needed.

Aim: To identify and synthesise research evidence exploring barriers to and facilitators of women GPs' careers.

Evaluation of the personality disorder positive outcomes programme (PDPOP) in general practice.

Background: GPs and primary care services have been identified as crucial to the care of people with personality disorder. Individuals living with personality disorder frequently face stigma and difficulties when accessing healthcare. Primary care staff often describe feeling demoralised, incompetent, hurt or angry after difficult interactions with patients.

Mapping the Energy Carrier Diffusion Tensor in Perovskite Semiconductors.

Understanding energy transport in semiconductors is critical for the design of electronic and optoelectronic devices. Semiconductor material properties, such as charge carrier mobility or diffusion length, are commonly measured in bulk crystals and determined using models that describe transport behavior in homogeneous media, where structural boundary effects are minimal. However, most emerging semiconductors exhibit nano- and microscale heterogeneity.

Simplified acid extraction and quantification of histones in human tumor cells.

Histones are essential nuclear proteins that package eukaryotic DNA into chromosomes, play a vital role in gene regulation, DNA replication, DNA repair and chromosome condensation. Understanding histone modifications is crucial for grasping biological and disease-related processes. Specific alterations in histone modifications serve as sensitive and selective biomarkers for conditions like cancer, impacting both tumor and immune cells and affecting their interactions.

Management of infants presenting with fever: a review of pan-London hospital guidelines and national guidelines.

Febrile infants often have self-limiting conditions. Differentiating them from infants with serious bacterial infections can be challenging. We aimed to understand how febrile infants are managed across London, by analysing the management steps from local clinical practical guidelines (CPGs) and comparing them to the national guideline 143 (NG143).

Irradiated Homologous Costal Cartilage Grafts in Complex Functional Septorhinoplasty.

Optimal results in complex nasal reconstruction, particularly in the context of post-traumatic and revision septorhinoplasty, often require the use of cartilage grafts to provide additional structural support to the nose. While autologous costal cartilage (ACC) has been traditionally used, this can be limited by donor site morbidity, increased operative time, and in some cases, lack of suitable cartilage for grafting. There has been a trend towards using irradiated homologous costal cartilage (IHCC) as an alternative source of graft material.

Understanding the Etiology of Externalizing Problems in Young Children: The Roles of Callous-Unemotional Traits and Irritability.

Objective: Callous-unemotional traits (CU), characterized as a lack of guilt and empathy; and irritability, a tendency to show anger and frustration; are 2 risk factors for externalizing behavioral problems. Externalizing problems, CU and irritability are all heritable. However, there is a dearth of studies examining the genetic and environmental associations between the 3 domains.

Scoping review: The effects of diet, physical activity and sleep on motor and physical fatigue in people with multiple sclerosis.

Physical and motor fatigue are debilitating symptoms common in multiple sclerosis (MS). Lifestyle interventions may be effective in managing MS-related fatigue. This scoping review aims to: (i) identify and summarise lifestyle interventions including those focused on diet, physical activity, and sleep, or multicomponent interventions for physical and motor fatigue management in MS; and (ii) provide recommendations for future research in this area.

Identifying Key Weather Factors Influencing Human Salmonellosis: A Conditional Incidence Analysis in England, Wales, and the Netherlands.

Objectives: This study aimed to improve the understanding of seasonal incidence pattern observed in salmonellosis by identifying the most influential weather factors, characterizing the nature of this association, and assessing whether it is geographically restricted or generalizable to other locations.

Methods: A novel statistical model was employed to estimate the incidence of salmonellosis conditional to various combinations of three simultaneous weather factors from 14 available. The analysis utilised daily salmonellosis cases reported from 2000 to 2016 along with detailed spatial and temporal weather data from England and Wales, and the Netherlands.

Dual controls of vapour pressure deficit and soil moisture on photosynthesis in a restored temperate bog.

Despite only covering ~3 % of the land mass, peatlands store more carbon (C) per unit area than any other ecosystem. This is due to the discrepancy between C fixed by the plants (Gross primary productivity (GPP)) and decomposition. However, this C is vulnerable to frequent, severe droughts and changes in the peatland microclimate.

Regulatory workshop on standardisation of clinical procedures, endpoints and data robustness of human challenge studies - A stakeholder meeting report.

Inno4Vac, a public-private partnership funded by the IMI2/EU/EFPIA Joint Undertaking (IMI2 JU), brings together academic institutions, SMEs, and pharmaceutical companies to accelerate and de-risk vaccine development. The project has made significant strides in the selection and production of challenge agents for influenza, respiratory syncytial virus (RSV), and toxigenic Clostridioides difficile for controlled human infection model studies (CHIMs). A regulatory workshop held on March 20, 2024, addressed the standardisation of clinical procedures, ethical considerations, endpoints, and data integrity, highlighting the ongoing initiatives related to these CHIMs.

Towards circular desalination: A new methodology for measuring and assessing resource flows and circular actions.

There is a lack of methodologies that quantitatively measure the intrinsic circularity of desalination systems, particularly focusing on resource flow traceability and circular actions. This study proposes a novel framework for assessing the circular economy performance of desalination systems. By integrating a systemic indicator selection and calculation approach, this methodology enables a comprehensive evaluation of intrinsic circularity in desalination processes.

Cortisol and testosterone coupling: Enhanced hormone reactivity to intercollegiate athletic competition in women athletes.

In a variety of settings, cortisol and testosterone are positively "coupled." That is, within-person fluctuations of these hormones occur in parallel, with increases and decreases in one hormone corresponding to increases and decreases in the other. A dataset comprised of salivary cortisol and testosterone levels from varsity women athletes from six different Emory University sports teams (volleyball 2002, 2005, and 2008; softball 2004; tennis 2009; soccer 2013) was used to explore the relationship between coupling and hormone reactivity to athletic competition.