The Use of Principal Component Analysis for Reduction in Sleep Quality and Quantity Data in Female Professional Soccer.

The main aim of the present study was to uncover multivariate relationships between sleep quantity and quality using principal component analysis (PCA) in professional female soccer players. A second aim was to examine the extent to which objective sleep quantity and quality variables can discriminate between perceived sleep. Ten objective sleep variables from the multisensory sleep-tracker were analyzed.

Glioblastoma: Clinical Presentation, Multidisciplinary Management, and Long-Term Outcomes.

Glioblastoma, the most common and aggressive primary brain tumor in adults, presents a formidable challenge due to its rapid progression, treatment resistance, and poor survival outcomes. Standard care typically involves maximal safe surgical resection, followed by fractionated external beam radiation therapy and concurrent temozolomide chemotherapy. Despite these interventions, median survival remains approximately 12-15 months, with a five-year survival rate below 10%.

Caught in the Crossfire: Unmasking the Silent Renal Threats of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia.

Background: Renal adverse drug reactions (ADRs) associated with tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia (CML) are relatively rare, and there is currently no standardized protocol for their management. Therefore, this study aimed to summarize renal ADRs related to TKIs use in CML and propose an evidence-based approach to monitor and manage these ADRs.

Methods: A systematic literature review was performed to identify renal ADRs associated with TKIs in CML.

Investigation and Assessment of AI's Role in Nutrition-An Updated Narrative Review of the Evidence.

Background: Artificial Intelligence (AI) technologies are now essential as the agenda of nutrition research expands its scope to look at the intricate connection between food and health in both an individual and a community context. AI also helps in tracing and offering solutions in dietary assessment, personalized and clinical nutrition, as well as disease prediction and management, such as cardiovascular diseases, diabetes, cancer, and obesity. This review aims to investigate and assess the different applications and roles of AI in nutrition and research and understand its potential future impact.

Attachment to Meat and Willingness Towards Cultured Alternatives Among Consumers: A Cross-Sectional Study in the UAE.

: The escalating global demand for meat, as a sequela of population growth, has led to unsustainable livestock production, resulting in a host of environmental and food security concerns. Various strategies have been explored to mitigate these issues, including the introduction of a novel food product, cultured meat. Cultured meat is not yet commercially available, yet public perceptions are already taking shape.

The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy.

The importance of functional food's role in human nutrition as well as in the prevention of diseases, especially the treatment of chronic diseases like cancer, is an innovative field of research. Based on the studies regarding the antioxidant potential of oyster mushroom extract, it is evident that it has anticancer properties. The current article reviews the health benefits of edible oyster-mushroom-derived bioactive compounds, and how they specifically activate or regulate the immune system by affecting the maturation, differentiation, and proliferation of immune cells, thereby inhibiting cancer cell metastasis and growth.

Chronic Exposure to Two Regimens of Waterpipe Smoke Elicits Lung Injury, Genotoxicity, and Mitochondrial Impairment with the Involvement of MAPKs Activation in Mice.

While the pulmonary effects of regular waterpipe smoking (R-WPS) are well-defined, the impact of occasional waterpipe smoking (O-WPS) on the lungs remains less established. This study investigated the pulmonary toxicity and underlying mechanisms of O-WPS versus R-WPS following 6 months of exposure, focusing on histopathology, inflammation in the lung, bronchoalveolar lavage fluid (BALF), and plasma, as well as oxidative stress, genotoxicity, mitochondrial dysfunction, and the expression of mitogen-activated protein kinases (MAPKs) in lung homogenates. Exposure to both O-WPS and R-WPS resulted in significant histological changes, including increased numbers of alveolar macrophages and lymphocytes, as well as interstitial fibrosis.

Lifetime Attributable Risk in Mammography Screenings in Dubai: The Influence of Breast Thickness and Age on Radiation Exposure.

This study investigated the lifetime attributable risk (LAR) of radiation-induced breast cancer from mammography screening in Dubai. It aimed to explore the relationship between breast thickness, patient age, and the associated radiation dose during mammographic examinations. A retrospective analysis was conducted on 2601 patients aged 40 to 69 across five screening facilities in Dubai's healthcare system.

A Critical Appraisal of System-Reported Organ Dose (OD) Versus Manually Calculated Mean Glandular Dose (MGD) in Dubai's Mammography Services.

: This study compares system-reported organ doses (ODs) to manually calculated mean glandular doses (MGDs) in mammography across multiple centers and manufacturers in Dubai. : A retrospective study of 2754 anonymized mammograms from six clinics in Dubai were randomly retrieved from a central dose survey database. Organ doses were documented along with other dosimetry information like kVp, mAs, filter, target, compression force, and breast thickness.

Parkinson's Disease Prediction: An Attention-Based Multimodal Fusion Framework Using Handwriting and Clinical Data.

Background: Neurodegenerative diseases (NGD) encompass a range of progressive neurological conditions, such as Alzheimer's disease (AD) and Parkinson's disease (PD), characterised by the gradual deterioration of neuronal structure and function. This degeneration manifests as cognitive decline, movement impairment, and dementia. Our focus in this investigation is on PD, a neurodegenerative disorder characterized by the loss of dopamine-producing neurons in the brain, leading to motor disturbances.

Minimum-Run Resolution IV Design for Optimized Bio Removal of Fe Using Aqueous Extract and Its Extract-Coated Silver Nanoparticles.

Biosorbents have demonstrated considerable potential for the remediation of metals in aqueous environments. An aqueous extract of L. (EiE) and its extract-coated silver nanoparticles have been prepared and employed for the removal of iron.

Bluues_cplx: Electrostatics at Protein-Protein and Protein-Ligand Interfaces.

(1) Background: Electrostatics plays a capital role in protein-protein and protein-ligand interactions. Implicit solvent models are widely used to describe electrostatics and complementarity at interfaces. Electrostatic complementarity at the interface is not trivial, involving surface potentials rather than the charges of surfacial contacting atoms.

The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes.

Bone lengthening and fracture repair depend on the anabolic properties of chondrocytes that function in an avascular milieu. The limited supply of oxygen and nutrients calls into question how biosynthesis and redox homeostasis are guaranteed. Here we show that glucose metabolism by the pentose phosphate pathway (PPP) is essential for endochondral ossification.

Design of an improved model using federated learning and LSTM autoencoders for secure and transparent blockchain network transactions.

With the advancement of this digital era and the emergence of DApps and Blockchain, secure, robust and transparent network transaction has become invaluable today. These traditional methods of securing the transactions and maintaining transparency have encountered many challenges. It includes some such issues as follows: data privacy, centralized vulnerability, inefficiency in fraud detection and much more.

Comparison of the stability of immediate dental implant placement in fresh molar extraction sockets in the maxilla and mandible: a controlled, prospective, non-randomized clinical trial.

The aim of this study was to assess the stability of immediate dental implants in fresh molar extraction sockets and to compare those placed in the maxilla and mandible. This was a controlled, prospective, non-randomized clinical trial; the maxilla was the test group and the mandible was the control group. Thirty patients with an unrestorable molar tooth who needed immediate implant placement were included.

Recent developments in photo-fermentative hydrogen evolution: Fundamental biochemistry and influencing factors a review.

The global shift towards renewable energy sources highlights the urgent need for sustainable hydrogen production, with photo-fermentative hydrogen evolution (PFHP) emerging as a promising solution. This review addresses the challenges and opportunities in optimizing PFHP, specifically the role of photosynthetic bacteria (PBS) in utilizing sunlight for hydrogen production. We focus on the key factors influencing PFHP, including light intensity, reactor design, substrate selection, carbon-to-nitrogen ratio, metal ions, temperature, pH, charge transfer and genetic engineering.

Bio-concentration of hazardous metals in migrant shorebirds in a key conservation reserve and adjoining areas on the west coast of India.

Heavy metal pollution is a growing environmental concern as it causes the degradation of wetlands by affecting the organisms at different trophic levels. Shorebirds typically feed on benthic invertebrates including polychaete worms, crustaceans and molluscs. Thus, the assessment of bioconcentration of heavy metals in shorebirds provides an insight into the extent of bioaccumulation of these hazardous metals in the upper trophic levels.

Knowledge, attitudes, and practices regarding urinary tract infections among women in the United Arab Emirates.

Background: Urinary tract infections (UTIs), which are infections of the kidneys, ureters, bladder, or urethra, are a worldwide public health concern. As compared to men, women are more prone to UTIs. There have been several studies that explore the knowledge, attitudes, and practices of women regarding UTIs in different countries, but no such study has been conducted in the UAE; therefore, we conducted this study in the UAE setting.

Laws about bodily damage originate from shared intuitions about the value of body parts.

From the biblical to the medieval wergild system and modern workers' compensation laws, laws about bodily damage may originate from cognitive mechanisms that capitalize on an enduring regularity: Different body parts vary in their incremental contributions to human functionality. To evaluate this hypothesis, we conducted a preregistered study with materials based on five legal codes from highly diverse cultures and historical eras: the Law of Æthelberht (Kent, approximately 600 CE), the Guta lag (Gotland, approximately 1220 CE), and workers' compensation laws from the United States, the Republic of Korea, and the United Arab Emirates; and 614 laypeople from the United States and India. The data indicate ordinal agreement in the values attached to body parts by ancient and modern lawmakers, as well as by laypeople in the United States and India.

Drug repurposing for sustainable antimicrobial use: exploring pharmacists' awareness, attitudes, facilitators and barriers.

This study utilized a validated questionnaire that aimed to assess pharmacists' awareness and attitude towards drug repurposing for antimicrobial use. Despite the reasonable awareness, pharmacists reported unfavourable attitudes. Pharmacists with a B.

Current and future burden of female breast cancer in the Middle East and North Africa region using estimates from GLOBOCAN 2022.

Breast cancer is the most diagnosed female cancer and the most common cause of cancer death in women in the Middle East and North Africa (MENA) region. In this study, we aimed to describe the current patterns of breast cancer among women in the MENA region and estimate the burden for the year 2050. We used the estimates of the breast cancer incidence and mortality from the GLOBOCAN 2022 database and predicted the burden of breast cancer in 2050 according to different scenarios.

Tungsten Diselenide Nanoparticles Produced via Femtosecond Ablation for SERS and Theranostics Applications.

Due to their high refractive index, record optical anisotropy and a set of excitonic transitions in visible range at a room temperature, transition metal dichalcogenides have gained much attention. Here, we adapted a femtosecond laser ablation for the synthesis of WSe nanoparticles (NPs) with diameters from 5 to 150 nm, which conserve the crystalline structure of the original bulk crystal. This method was chosen due to its inherently substrate-additive-free nature and a high output level.

The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells.

The Kynurenine pathway is crucial in metabolizing dietary tryptophan into bioactive compounds known as kynurenines, which have been linked to glucose homeostasis. The aryl hydrocarbon receptor (AhR) has recently emerged as the endogenous receptor for the kynurenine metabolite, kynurenic acid (KYNA). However, the specific role of AhR in pancreatic β-cells remains largely unexplored.

Functional and Lateral Asymmetry of the Knee Joint Muscles Measured Using Tensiomyography (TMG) in Professional Football Players of Different Playing Positions.

: The aim of this study is to determine whether different playing positions in football influence muscle asymmetry, which is a common cause of injuries in football. This study aimed to determine the difference in the functional and lateral asymmetry of the knee joint muscles measured using tensiomyography (TMG) between football players of different playing positions. : This study included 52 professional football players (25.

Dysphagia in Rare Diseases and Syndromes: Current Approaches to Management and Therapeutic Innovations-A Systematic Review.

This study presents a comprehensive investigation into the correlation between Rare Diseases and Syndromes (RDS) and the dysphagic disorders manifested during childhood and adulthood in affected patients. Dysphagia is characterized by difficulty or an inability to swallow food of any consistency, as well as saliva or medications, from the oral cavity to the stomach. RDS often present with complex and heterogeneous clinical manifestations, making it challenging to develop standardized diagnostic and therapeutic approaches.